Dementia and Elderly Care- December 2013

News Brief: Progress Across Five Frontiers

(1)   Potential Prevention of Cell Death in Neurodegenerative Diseases

A chemical which appears to be able to stop brain cell death in neurodegenerative diseases could provide the key (in the long-term) for halting the progress of Alzheimer’s Disease, Parkinson’s Disease and Huntingdon’s Disease (plus the rarer prion diseases). For further details, see:

Gallagher, J. (2013). Alzheimer’s breakthrough: cure or hype? London: BBC Health News, October 10th2013. Full Text Link.

This relates to:

Moreno, J. A. Halliday, M. [and] Molloy, C. [et al] (2013). Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice. Science Translational Medicine. October 9th2013; 5(206): 206ra138.

Moreno, JA. Radford, H. [and] Peretti, D. [et al] (2012). Sustained translational repression by eIF2α-P mediates prion neurodegeneration. Nature. May 6th2012; 485(7399): 507-11. Full Text Link.

Links to the full-text of other recent articles on dementia and neurodegenerative disease-related research feature in the section entitled Neuroscientific / Neurological Researchbelow.

(2)   Genetics Research

Geneticists from 145 academic institutions collaborating internationally have mapped the known genetic determinants of Alzheimer’s disease. For further details, see:

More gene changes have role in Alzheimer’s disease. London: NHS Choices; Behind the Headlines, October 28th2013. 

This relates to the following article:

Lambert, JC. Ibrahim-Verbaas, CA. [and] Harold, D. [et al] (2013). Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease. Nature Genetics, Epub ahead of print: October 27th2013.

Links to the full-text of recent articles on research into genetics appear in the section entitled Genetic below.

(3)   State of the Nation Report

A new Department of Health report reviews current practice and knowledge about dementia care, support and research in England. It covers the prevalence and the societal cost of dementia, and gives an overview of progress on: prevention; diagnosis; living well with dementia; dementia awareness, education and training; the development of dementia friendly communities; and dementia-related research. This report also indicates where improvements are needed, including where better data is required. Refer to:

Dementia care and support: review of quality and extent of dementia care. London: Department of Health, November 29th2013.

(4)   Government’s Response to Francis Inquiry Report (Department of Health)

The Government has released a full response to Robert Francis QC’s report into poor standards of care at Mid Staffordshire NHS Foundation Trust, published in February 2013. It develops the Government’s initial response: Patients First and Foremost, which was published in March 2013. Further details are available at:

Mid Staffordshire NHS FT public inquiry: government response. London: Department of Health, November 19th2013.

Brief references and links to other recent important reports appear in the section entitled Announcements below.

(5)   The First G8 Dementia Summit

The UK is hosting the G8 Summit On Dementia Research in London on December 11th2013. The summit aims to develop a coordinated international approach to research into dementia, involving Governments, the research community, non-profit organisations and industry. For a brief overview, see:

Hunt, J. (2013). The world-wide challenge of dementia: Jeremy Hunt talks about using the G8 summit on dementia to seek further international collaboration. London: Department of Health, August 19th2013. See also News Brief: Recent Reports & Announcementsbelow.

A selection of publications which, collectively, are likely to be the subject of discussions at the G8 Dementia Summit appear in the sections entitled Neuroscientific / Neurological Researchand Genetic Researchbelow.

The G8 Dementia Summit will not be restricted to big-budget laboratory-based scientific research. It will also address new models of care, social investment, research finance and encouraging collaboration between industry and academics.

News Brief: Recent Reports & Announcements

Black and minority ethnic communities and dementia: Where are we now? Better Health. London: Race Equality Foundation, November 2013. Better Health Briefing No. 30.

Cold weather plan for England 2013. London: Public Health England, October 25th2013.

Commissioning for Value: CCG insights packs [official website]. London: NHS Right Care, October 2013.

Co-ordinated care for people with complex chronic conditions. London: The King’s Fund / Aetna and the Aetna Foundation, October 2013.

Co-production in social care: what it is and how to do it. London: Social Care Institute for Excellence (SCIE), October 2013.

Delivering better services for people with long-term conditions. London: King’s Fund, October 2013.

Dementia care and support: review of quality and extent of dementia care. London: Department of Health, November 29th2013.

Dementia self-assessment framework. London: Department of Health, October 16th2013.

Department of Health 2013-14 Corporate Plan (updated). London: Department of Health, October 2nd2013.

Diagnostics: The NHS Atlas of Variation in Diagnostic Services. Oxford: NHS Right Care, November 2013.

Excess Winter Mortality in England and Wales, 2012/13 (Provisional) and 2011/12 (Final). London: Office for National Statistics, November 26th2012.  

announced. London: NHS England, November 1st 2013.

Mid Staffordshire NHS FT public inquiry: government response. London: Department of Health, November 19th2013.

National Audit of Intermediate Care Report 2013. London: NHS Benchmarking Network, November 2012.

New report from PHE shows improvements in end of life care. London: Public Health England, November 4th2013.

NHS hospitals complaints system review. London: Department of Health, October 28th2013.

The NHS Mandate. London: Department of Health, November 12th2013.

NHS Outcomes Framework 2014 to 2015. NHS Outcomes Framework 2014 to 2015. London: Department of Health, November 12th2013.

Personalised GP care will bring back old-fashioned family doctors. London: Department of Health, November 15th2013.

Policy Brief: The Global Impact of Dementia 2013-2050. London: Alzheimer’s Disease International (ADI), December 2013.

Sir Bruce Keogh proposes new blueprint for urgent and emergency care across England. London: NHS England, November 13th2013.

State of Care report shows ‘avoidable’ emergency admissions are increasing. London: Care Quality Commission (CQC), November 2013.

State of Care 2012/13. The state of health care and adult social care in England. Technical Annex 3: Dementia thematic review. London: Care Quality Commission (CQC), November 2013.

Acute Hospital Care

Treacy, D. Sherrington, C. Schurr, K. (2013). Balance circuit classes to improve balance among rehabilitation inpatients: a protocol for a randomised controlled trial.BMC Geriatrics. July 20th2013; 13(1):75. [Epub ahead of print].Full Text Link.

Goldberg, SE. Bradshaw, LE. Kearney, FC. [et al] (2013). Care in specialist medical and mental health unit compared with standard care for older people with cognitive impairment admitted to general hospital: randomised controlled trial (NIHR TEAM trial). BMJ. July 2nd2013; 347:f4132. Full Text Link.

Whyte, A. (2013). Excuses. Nursing Standard. September 25th2013; 28(4):26-7.

Moore, ZE. Webster, J. (2013). ulcers. Cochrane Database of Systematic Reviews (Online). August 18th2013; Issue 8: No. CD009362. Full Text Link.

Fox, MT. Persaud, M. Maimets, I. [et al] (2013). Effectiveness of early discharge planning in acutely ill or injured hospitalized older adults: a systematic review and meta-analysis.BMC Geriatrics. July 6th2013;13:70. Full Text Link.

Kosse, NM. Dutmer, AL. Dasenbrock, L. [et al] (2013). Effectiveness and feasibility of early physical rehabilitation programs for geriatric hospitalized patients: a systematic review.BMC Geriatrics. October 10th2013; 13(1):107. [Epub ahead of print].Full Text Link.

Chan, RJ. Webster, J. (2013). Dying. Cochrane Database of Systematic Reviews (Online). November 18th2013; Issue 11: No. CD008006. Full Text Link.

Sunnerhagen, KS. Danielsson, A. Rafsten, L. [et al] (2013). Gothenburg very early supported discharge study (GOTVED) NCT01622205: a block randomized trial with superiority design of very early supported discharge for patients with stroke.BMC Neurology. June 24th2013;13:66. Full Text Link.

Andrews, J. (2013).A guide to creating a dementia-friendly ward.Nursing Times. February 26th – March 4th2013;109(8):20-1.

Zapatero, A. Barba, R. Canora, J. [et al] (2013). Hip fracture in hospitalized medical patients.BMC Musculoskeletal Disorders. January 8th2013;14:15. Full Text Link.

George, J. Long, S. Vincent, C. (2013). How can we keep patients with dementia safe in our acute hospitals? A review of challenges and solutions.Journal of the Royal Society of Medicine. September 2013;106(9):355-61.

Edmans, J. Bradshaw, L. Gladman, JR. [et al] (2013). The Identification of Seniors at Risk (ISAR) score to predict clinical outcomes and health service costs in older people discharged from UK acute medical units.Age and Ageing. November 2013;42(6):747-53. Full Text Link.

Nilsson, A. Lindkvist, M. Rasmussen, BH. [et al](2013). Measuring levels of person-centeredness in acute care of older people with cognitive impairment: evaluation of the POPAC scale.BMC Health Services Research. August 19th2013;13:327. Full Text Link.

Eklund, K. Wilhelmson, K. Gustafsson, H. [et al] (2013). One-year outcome of frailty indicators and activities of daily living following the randomised controlled trial; "Continuum of care for frail older people".BMC Geriatrics. July 22nd2013;13(1):76. [Epub ahead of print].Full Text Link.

Fayyaz, J. Khursheed, M. Mir, MU. [et al] (2013). Pattern of emergency department visits by elderly patients: study from a tertiary care hospital, Karachi.BMC Geriatrics. August 12th2013;13:83. Full Text Link.

Salvi, F. Mattioli, A. Giannini, E. [et al] (2013). Pattern of use and presenting complaints of older patients visiting an Emergency Department in Italy.Aging Clinical and Experimental Research. October 2013;25(5):583-90

Edvardsson, D. Nilsson, A. Fetherstonhaugh, D. [et al] (2013). The person-centred care of older people with cognitive impairment in acute care scale (POPAC).Journal of Nursing Management. January 2013;21(1):79-86. Full Text Link.

Asmus-Szepesi, KJ. de Vreede, PL. Flinterman, LE. [et al] (2013). Prognosis of hospitalised older people with different levels of functioning: a prospective cohort study.Age and Ageing. November 2013;42(6):803-9.

Saczynski J, McManus D, Gurwitz J, Goldberg R, Kiefe C. PS1-34: Clinical factors associated with cognitive function in patients hospitalized for acute coronary syndromes: preliminary findings from TRACE-CORE. Clinical Medicine and Research. September 2013;11(3):135. Full Text Link.

Scheffer, AC. van Hensbroek, PB. van Dijk, N. [et al].Risk factors associated with visiting or not visiting the Accident & Emergency department after a fall.BMC Health Services Research. July 26th2013;13:286. Full Text Link.

Jackson, TA. Naqvi, SH. Sheehan, B. (2013). Screening for dementia in general hospital inpatients: a systematic review and meta-analysis of available instruments.Age and Ageing. November 2013;42(6):689-95

Morris, ZS. Fyfe, M. Momen, N. [et al] (2013). Understanding hospital admissions close to the end of life (ACE) study.BMC Health Services Research. March 11th2013;13:89. Full Text Link.

Carers and Caring

Sheehan, B. Lall, R. Gage, H. [et al] (2013). A 12-month follow-up study of people with dementia referred to general hospital liaison psychiatry services.Age and Ageing. November 2013;42(6):786-90.

Doran, DM. Hirdes, JP. Blais, R. [et al] (2013). Adverse events among Ontario home care clients associated with emergency room visit or hospitalization: a retrospective cohort study.BMC Health Services Research. June 22nd2013;13:227. Full Text Link.

Hazzan, AA. Ploeg, J. Shannon, H. [et al] (2013). Association between caregiver quality of life and the care provided to persons with Alzheimer's disease: protocol for a systematic review. Syst Rev. March 13th2013;2:17. Review. Full Text Link.

Trueland, J. (2013). Bring back memories.Nursing Standard. February 27th - March 5th2013;27(26):16-8. Full Text Link.

van der Steen, JT. Onwuteaka-Philipsen, BD. Knol, DL. [et al] (2013). Caregivers' understanding of dementia predicts patients' comfort at death: a prospective observational study.BMC Medicine. April 11th2013;11:105. Full Text Link.

Watanabe, M. Yamamoto-Mitani, N. Nishigaki, M. [et al] (2013). Care managers' confidence in managing home-based end-of-life care: a cross-sectional study.BMC Geriatrics. July 1st2013;13:67. Full Text Link.

Livingston, G. Barber, J. Rapaport, P. [et al] (2013). Clinical effectiveness of a manual based coping strategy programme (START, STrAtegies for RelaTives) in promoting the mental health of carers of family members with dementia: pragmatic randomised controlled trial. BMJ. October 25th2013;347:f6276. Full Text Link.

Jenkins, C. McKay, A. (2013). A collaborative approach to health promotion in early stage dementia.Nursing Standard. May 8-14th2013;27(36):49-57; quiz 58. Full Text Link.

Jenkins, C. McKay, A. (2013). Collaborative health promotion in middle and later stages of dementia.Nursing Standard. May 15-21st2013;27(37):49-56; quiz 58, 60. Full Text Link.

van der Ploeg, ES. Bax, D. Boorsma, M. [et al] (2013). A cross-sectional study to compare care needs of individuals with and without dementia in residential homes in the Netherlands.BMC Geriatrics. May 24th2013;13:51. Full Text Link.

Morley, JE. Dementia with Lewy bodies: a common condition in nursing homes?Journal of the American Medical Directors Association. October 2013;14(10):713-4.

Waugh, A. Austin, A. Manthorpe, J. [et al] (2013). Designing a complex intervention for dementia case management in primary care.BMC Family Practice. July 17th2013;14:101. Full Text Link.

Whitney, J. Jackson, SH. Close, JC. [et al] (2013). Development and validation of a fall-related impulsive behaviour scale for residential care.Age and Ageing. November 2013;42(6):754-8.

Moore, ZE. Webster, J. (2013). Dressings and topical agents for preventing pressure ulcers.Cochrane Database of Systematic Reviews (Online). August 18th2013; Issue 8: No. CD009362. Full Text Link.

Halek, M. Dichter, MN. Quasdorf, T. [et al] (2013). The effects of dementia care mapping on nursing home residents' quality of life and staff attitudes: design of the quasi-experimental study Leben-QD II.BMC Geriatrics. June 1st2013;13:53. Full Text Link.

Kuehn, BM. (2013).Efforts stall to curb nursing home antipsychotic use. JAMA. September 18th2013;310(11):1109-10.

Chan, RJ. Webster, J. (2013). End-of-life care pathways for improving outcomes in caring for the dying.Cochrane Database of Systematic Reviews (Online). November 18th2013; Issue 11: No. CD008006. Full Text Link.

Carlisle, D. (2013). An end to isolation.Nursing Standard. October 23rd - 29th2013;28(8):26-7.

Logue, MD. Drago, J. (2013). Evaluation of a modified community based care transitions model to reduce costs and improve outcomes.BMC Geriatrics. September 12th2013;13(1):94. [Epub ahead of print.Full Text Link.

Clare, L. Bayer, A. Burns, A. [et al] (2013). Goal-oriented cognitive rehabilitation in early-stage dementia: study protocol for a multi-centre single-blind randomised controlled trial (GREAT). Trials. May 27th2013;14:152. Full Text Link.

Duggleby, W. Schroeder, D. Nekolaichuk, C. (2013). Hope and connection: the experience of family caregivers of persons with dementia living in a long term care facility.BMC Geriatrics. October 20th2013;13(1):112. [Epub ahead of print].Full Text Link.

Chiu, M. Wesson, V. Sadavoy, J. (2013). Improving caregiving competence, stress coping, and mental well-being in informal dementia carers. World Journal of Psychiatry. September 22nd 2013; 3(3): 65-73. Full Text Link.

Morita, K. Kobayashi, M. (2013). Interactive programs with preschool children bring smiles and conversation to older adults: time-sampling study.BMC Geriatrics. October 18th2013;13(1):111. [Epub ahead of print].Full Text Link.

Mullick, A. Martin, J. Sallnow, L. (2013). An introduction to advance care planning in practice. BMJ. October 21st2013;347:f6064. Full Text Link.

Close, H. Hancock, H. Mason, JM. [et al] (2013). "It's Somebody else's responsibility" - perceptions of general practitioners, heart failure nurses, care home staff, and residents towards heart failure diagnosis and management for older people in long-term care: a qualitative interview study.BMC Geriatrics. July 5th2013;13:69. Full Text Link.

Keating, M. Long, J. Wright, J. (2013).Leading culture change to improve dementia care.Nursing Times. February 26th – March 4th2013;109(8):16-8. Full Text Link.

Stevens, E. (2013). The Mental Capacity Act 2005: considerations for nursing practice.Nursing Standard. September 11-17th2013;28(2):35-9.

Iliffe, S. Davies, N. Vernooij-Dassen, M. [et al]; IMPACT research team. (2013). Modelling the landscape of palliative care for people with dementia: a European mixed methods study.BMC Palliative Care. August 12th2013;12(1):30. Full Text Link.

Allen, D. (2013). More than just a listening ear.Nursing Standard. August 7-13th2013;27(49):22-3. Full Text Link.

Cummings, GG. Reid, RC. Estabrooks, CA. [et al] (2013). Older Persons' Transitions in Care (OPTIC): a study protocol.BMC Geriatrics . December 14th2012;12:75. Full Text Link.

Rodríguez-Martín, B. Martínez-Andrés, M. Cervera-Monteagudo, B. [et al] (2013). Perception of quality of care among residents of public nursing-homes in Spain: a grounded theory study.BMC Geriatrics. June 28th2013;13(1):65. [Epub ahead of print].Full Text Link.

Atkins, J. Naismith, SL. Luscombe, GM. [et al] (2013). A preliminary study of aged care facility staff indicates limitations in awareness of the link between depression and physical morbidity.BMC Geriatrics. April 9th2013;13:30. Full Text Link.

Fu, CY. Moyle, W. Cooke, M. (2013). A randomised controlled trial of the use of aromatherapy and hand massage to reduce disruptive behaviour in people with dementia.BMC Complementary and Alternative Medicine. July 10th2013;13:165. Full Text Link.

Boyle, G. (2013). 'She's usually quicker than the calculator': financial management and decision-making in couples living with dementia.Health and Social Care in the Community. September 2013;21(5):554-62.

Leontjevas, R. Gerritsen, DL. Smalbrugge, M. [et al] (2013).A structural multidisciplinary approach to depression management in nursing-home residents: a multicentre, stepped-wedge cluster-randomised trial. Lancet. June 29th2013;381(9885):2255-64. Full Text Link.

Travers, CM. Beattie, E. Martin-Khan, M. [et al] (2013). A survey of the Queensland healthcare workforce: attitudes towards dementia care and training.BMC Geriatrics. September 30th2013;13(1):101. [Epub ahead of print].Full Text Link.

Minkman, MM. Vermeulen, RP. Ahaus, KT. [et al] (2013).A survey study to validate a four phases development model for integrated care in the Netherlands.BMC Health Services Research. June 13th2013;13:214.

Stokes, G. (2013). Tackling communication challenges in dementia.Nursing Times. February 26th - March 4th2013;109(8):14-5. Full Text Link.

Lynch, E. (2013). Thinking outside the box.Nursing Standard. September 26th – October 2nd2012;27(4):23.

van der Steen, JT. Hertogh, CM. de Graas, T. [et al]. (2013). Translation and cross-cultural adaptation of a family booklet on comfort care in dementia: sensitive topics revised before implementation.Journal of Medical Ethics. February 2013;39(2):104-9.

White, J. (2013). Turning learning into action.Nursing Standard. August 21-27th2013;27(51):69. Full Text Link.

Connolly, A. Campbell, S. Gaehl, E. [et al] (2013). Under-provision of medical care for vascular diseases for people with dementia in primary care: a cross-sectional review.British Journal of General Practice. February 2013;63(607):e88-96.

Chiatti, C. Masera, F. Rimland, JM. [et al]; UP-TECH research group (2013). The UP-TECH project, an intervention to support caregivers of Alzheimer's disease patients in Italy: study protocol for a randomized controlled trial. Trials. May 28th2013;14:155. Full Text Link.

Murphy, J. Oliver, T. (2013). The use of Talking Mats to support people with dementia and their carers to make decisions together.Health and Social Care in the Community. March 2013;21(2):171-80.

Smith, AK. Lo, B. Sudore, R. (2013). When previously expressed wishes conflict with best interests.JAMA Internal Medicine. July 8th2013;173(13):1241-5. Full Text Link.

Delirium

Khan, BA. Calvo-Ayala, E. Campbell, N. [et al] (2013). Clinical decision support system and incidence of delirium in cognitively impaired older adults transferred to intensive care.American Journal of Critical Care. May2013;22(3):257-62. Full Text Link.

Hassamal, S. Pandurangi, A. Venkatachalam, V. [et al] (2013). Delayed onset and prolonged ECT-related delirium.Case Reports in Psychiatry. 2013;840425. Full Text Link.

Holt, R. Young, J. Heseltine, D. (2013). Effectiveness of a multi-component intervention to reduce delirium incidence in elderly care wards.Age and Ageing. November 2013;42(6):721-7.

Maclullich, AM. Anand, A. Davis, DH. [et al] (2013). New horizons in the pathogenesis, assessment and management of delirium.Age and Ageing. November 2013;42(6):667-74. Full Text Link.

Mariz, J. Santos, NC. Afonso, H. [et al] (2013). Risk and clinical-outcome indicators of delirium in an emergency department intermediate care unit (EDIMCU): an observational prospective study.BMC Emergency Medicine. January 29th2013;13:2. Full Text Link.

Yang, FM. Jones, RN. Inouye, SK. [et al] (2013). Selecting optimal screening items for delirium: an application of item response theory.BMC Medical Research Methodology. January 22nd2013;13:8. Full Text Link.

Diagnosis, Screening, Assessment and Symptoms

Dickerson, BC. Wolk, DA.; Alzheimer's Disease Neuroimaging Initiative (2013). Biomarker-based prediction of progression in MCI: Comparison of AD signature and hippocampal volume with spinal fluid amyloid-β and tau.Frontiers in Aging Neuroscience. October 11th2013;5:55. Full Text Link.

Can the eyes help diagnose Alzheimer’s Disease? Georgetown [USA]: Georgetown University Medical Center (GUMC), November 13th2013. Full Text Link.

Premi, E. Gazzina, S. Bozzali, M. [et al].(2013). Cognitive reserve in granulin-related frontotemporal dementia: from preclinical to clinical stages. PLoS One. September 9th2013;8(9):e74762. Full Text Link.

Kandimalla, RJ. Prabhakar, S. Wani, WY. [et al] (2013). CSF p-Tau levels in the prediction of Alzheimer's disease. Biology Open. September 4th 2013; 2(11): 1119-24. Full Text Link.

Alegret, M. Espinosa, A. Valero, S. [et al] (2013). Cut-off scores of a Brief Neuropsychological Battery (NBACE) for Spanish individual adults older than 44 years old. PLoS One. October 16th2013;8(10):e76436. Full Text Link.

Vannier-Nitenberg, C. Dauphinot, V. Bongue, B. [et al] (2013). Early detection of memory impairment in people over 65 years old consulting at Health Examination Centers for the French health insurance: the EVATEM protocol.BMC Geriatrics. June 6th2013;13:55. Full Text Link.

Moretti, DV. Paternicò, D. Binetti, G. [et al] (2013). EEG upper/low alpha frequency power ratio relates to temporo-parietal brain atrophy and memory performances in mild cognitive impairment.Frontiers in Aging Neuroscience. October 25th2013;5:63. Full Text Link.

Braverman, ER. Blum, K. Damle, UJ. [et al] (2013). Evoked potentials and neuropsychological tests validate Positron Emission Topography (PET) brain metabolism in cognitively impaired patients. PLoS One. 2013;8(3):e55398. Full Text Link.

Trueland, J. (2013). Is early diagnosis best?Nursing Standard. November 6th2013;28(10):20-2.

Zhang, Y. Wang, S. Ji, G. [et al] (2013). An MR brain images classifier system via particle swarm optimization and kernel support vector machine.ScientificWorldJournal. September 16th2013;130134. Full Text Link.

Leclerc, B. Abulrob, A. (2013). Perspectives in molecular imaging using staging biomarkers and immunotherapies in Alzheimer's disease. ScientificWorldJournal. 2013;589308. Epub February 5th2013. Review. Full Text Link.

Le Couteur, DG. Doust, J. [and] Creasey, H. [et al] (2013). Political drive to screen for pre-dementia: not evidence based and ignores the harms of diagnosis. BMJ, September 9th2013, 347, f5125. (Click here to view the PubMed record).Full Text Link

Saczynski J, McManus D, Gurwitz J, Goldberg R, Kiefe C. PS1-34: Clinical factors associated with cognitive function in patients hospitalized for acute coronary syndromes: preliminary findings from TRACE-CORE.Clinical Medicine and Research. September 2013;11(3):135. Full Text Link.

Jackson, TA. Naqvi, SH. Sheehan, B. (2013). Screening for dementia in general hospital inpatients: a systematic review and meta-analysis of available instruments.Age and Ageing. November 2013;42(6):689-95.

Lee, L. Weston, WW. Heckman, G. [et al] (2013). Structured approach to patients with memory difficulties in family practice.Canadian Family Physician. March 2013;59(3):249-54. Full Text Link.

O'Caoimh, R. Gao, Y. Gallagher, PF. [et al] (2013). Which part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia?Age and Ageing. May2013;42(3):324-30. Full Text Link.

Epidemiological Studies, Risk Factors and Prevention

Doran, DM. Hirdes, JP. Blais, R. [et al] (2013).Adverse events among Ontario home care clients associated with emergency room visit or hospitalization: a retrospective cohort study.BMC Health Services Research. June 22nd2013;13:227. Full Text Link.

Pocchiari, M. Poleggi, A. Puopolo, M. [et al] (2013). Age at death of Creutzfeldt-Jakob disease in subsequent family generation carrying the E200K mutation of the prion protein gene. PLoS One. 2013;8(4):e60376. Full Text Link.

Alladi, S. Bak, TH. [and] Duggirala, V. [et al] (2013). Bilingualism delays age at onset of dementia, independent of education and immigration status. Neurology, Published online November 6th2013.

Dahl, AK. Hassing, LB. Fransson, EI. [et al] (2013). Body mass index across midlife and cognitive change in late life. International Journal of Obesity. February 2013;37(2):296-302. Full Text Link.

Zeki Al Hazzouri, A. Haan, MN. Neuhaus, JM. [et al] (2013). Cardiovascular risk score, cognitive decline, and dementia in older Mexican Americans: the role of sex and education.Journal of the American Heart Association. April 22nd2013;2(2):e004978. Full Text Link.

Yang, Z. Slavin, MJ. Sachdev, PS. (2013). Dementia in the oldest old.Nature Reviews. Neurology. July 2013;9(7):382-93.

Luppa, M. Luck, T. Ritschel, F. [et al] (2013). Depression and incident dementia. An 8-year population-based prospective study. PLoS One. 2013;8(3):e59246. Full Text Link.

Borenstein, J. Aronow, HU. Bolton, LB. [et al] (2013). Early recognition of risk factors for adverse outcomes during hospitalization among Medicare patients: a prospective cohort study.BMC Geriatrics. July 8th2013;13:72. Full Text Link.

Underwood, M. Lamb, SE. Eldridge, S. [et al] (2013). Exercise for depression in elderly residents of care homes: a cluster-randomised controlled trial. Lancet. July 6th2013;382(9886):41-9. Full Text Link.

Dams-O'Connor, K. Spielman, L. Hammond, FM. [et al] (2013). An exploration of clinical dementia phenotypes among individuals with and without traumatic brain injury. NeuroRehabilitation. 2013;32(2):199-209. Full Text Link.

Sachdev, PS. Lipnicki, DM. Crawford, J. [et al]; Sydney Memory, Ageing Study Team (2013). Factors predicting reversion from mild cognitive impairment to normal cognitive functioning: a population-based study. PLoS One. 2013;8(3):e59649. Full Text Link.

Tolppanen, AM. Lavikainen, P. Soininen, H. [et al] (2013). Incident hip fractures among community dwelling persons with Alzheimer's Disease in a Finnish nationwide register-based cohort. PLoS One. 2013;8(3):e59124. Full Text Link.

Brooks, SJ. Benedict, C. Burgos, J. [et al] (2013).Late-life obesity is associated with smaller global and regional gray matter volumes: a voxel-based morphometric study.International Journal of Obesity. 2013 Feb;37(2):230-6. Full Text Link.

Chan, V. Zagorski, B. Parsons, D. [et al] (2013). Older adults with acquired brain injury: a population based study.BMC Geriatrics. September 23rd2013;13(1):97. [Epub ahead of print].Full Text Link.

Saczynski J, McManus D, Gurwitz J, Goldberg R, Kiefe C. PS1-34: Clinical factors associated with cognitive function in patients hospitalized for acute coronary syndromes: preliminary findings from TRACE-CORE.Clinical Medicine and Research. September 2013;11(3):135. Full Text Link.

Badia, JG. Santos, AB. Segura, JC. [et al] (2013).Predictors of mortality among elderly dependent home care patients.BMC Health Services Research. August 15th2013;13(1):316. [Epub ahead of print].Full Text Link.

Tola-Arribas, MA. Yugueros, MI. Garea, MJ. [et al] (2013). Prevalence of dementia and subtypes in Valladolid, Northwestern Spain: The DEMINVALL Study. PLoS One. October 17th2013;8(10):e77688. Full Text Link.

Evans, SJ. Douglas, I. Rawlins, MD. [et al] (2013). Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records.Journal of Neurology, Neurosurgery, and Psychiatry. October 2013;84(10):1156-60. Full Text Link.

Ward, A. Tardiff, S. [and] Dye, C. [et al] (2013). Rate of conversion from prodromal Alzheimer’s disease to Alzheimer’s dementia: a systematic review of the literature. Dementia and Geriatric Cognitive Disorders Extra, September 28th2013, Vol.3(1), pp.320-32. Full Text Link.

Park, H. Suk, SH. Cheong, JS. [et al] (2013). Tooth loss may predict poor cognitive function in community-dwelling adults without dementia or stroke: the PRESENT Project.Journal of Korean Medical Science. October 2013;28(10):1518-21. Full Text Link.

Winkler, JM. Fox, HS. (2013). Transcriptome meta-analysis reveals a central role for sex steroids in the degeneration of hippocampal neurons in Alzheimer's disease.BMC Systems Biology. June 26th2013;7:51. Full Text Link.

Matthews, FE. Arthur, A. Barnes, LE. [et al]; Medical Research Council Cognitive Function and Ageing Collaboration. (2013). A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II. Lancet. October 26th2013;382(9902):1405-12. Full Text Link.

Doets, EL. van Wijngaarden, JP. Szczecinska, A. [et al] (2013). Vitamin B12 intake and status and cognitive function in elderly people.Epidemiological Reviews. December 5th2012. [Epub ahead of print].

Falls-Related

Sakurai, R. Fujiwara, Y. Ishihara, M. [et al] (2013). Age-related self-overestimation of step-over ability in healthy older adults and its relationship to fall risk.BMC Geriatrics. May 7th2013;13:44. Full Text Link.

Gschwind, YJ. Kressig, RW. Lacroix, A. [et al] (2013). A best practice fall prevention exercise program to improve balance, strength / power, and psychosocial health in older adults: study protocol for a randomized controlled trial.BMC Geriatrics. October 9th2013;13(1):105. [Epub ahead of print.Full Text Link.

Klein, D. Nagel, G. Kleiner, A. [et al] (2013). Blood pressure and falls in community-dwelling people aged 60 years and older in the VHM&PP cohort.BMC Geriatrics. May 21st2013;13:50. Full Text Link.

de Negreiros Cabral, K. Perracini, MR. Soares, AT. [et al] (2013).Effectiveness of a multifactorial falls prevention program in community-dwelling older people when compared to usual care: study protocol for a randomised controlled trial (Prevquedas Brazil).BMC Geriatrics. March 15th2013;13:27. Full Text Link.

de Vries, OJ. Peeters, G. Elders, P. [et al] (2013). The elimination half-life of benzodiazepines and fall risk: two prospective observational studies.Age and Ageing. November 2013;42(6):764-70.

Damián, J. Pastor-Barriuso, R. Valderrama-Gama, E. [et al] (2013). Factors associated with falls among older adults living in institutions.BMC Geriatrics. January 15th2013;13:6. Full Text Link.

Ungar, A. Rafanelli, M. Iacomelli, I. [et al] (2013). Fall prevention in the elderly.Clinical Cases in Mineral Bone Metabolism. May2013;10(2):91-95. Review. Full Text Link.

Stenhagen, M. Ekström, H. Nordell, E. [et al] (2013). Falls in the general elderly population: a 3- and 6- year prospective study of risk factors using data from the longitudinal population study 'Good ageing in Skane'.BMC Geriatrics. August 7th2013;13:81. Full Text Link.

Uzor, S. Baillie, L. Skelton, DA. [et al] (2013).Falls prevention advice and visual feedback to those at risk of falling: study protocol for a pilot randomized controlled trial. Trials. March 19th2013;14:79. Full Text Link.

Wesson, J. Clemson, L. Brodaty, H. [et al] (2013). A feasibility study and pilot randomised trial of a tailored prevention program to reduce falls in older people with mild dementia.BMC Geriatrics. September 3rd2013;13(1):89. [Epub ahead of print].Full Text Link.

Frontotemporal Dementia

Meisler, MH. Grant, AE. Jones, JM. [et al] (2013). C9ORF72 expansion in a family with bipolar disorder. Bipolar Disorders. May2013;15(3):326-32. Full Text Link.

Landqvist Waldö, M. Frizell Santillo, A. Passant, U. [et al] (2013). Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia.BMC Neurology. May 29th2013;13:54. Full Text Link.

Premi, E. Gazzina, S. Bozzali, M. [et al].(2013). Cognitive reserve in granulin-related frontotemporal dementia: from preclinical to clinical stages. PLoS One. September 9th2013;8(9):e74762. Full Text Link.

Hughes, LE. Rowe, JB. (2013). The impact of neurodegeneration on network connectivity: a study of change detection in frontotemporal dementia.Journal of Cognitive Neuroscience. May2013;25(5):802-13. Full Text Link.

Roca, M. Manes, F. Gleichgerrcht, E. [et al] (2013). Intelligence and executive functions in frontotemporal dementia. Neuropsychologia. March 2013;51(4):725-30. Full Text Link.

Genetic Research

Ma, L. Wei, L. Wu, F. [et al] (2013). Advances with microRNAs in Parkinson's disease research.Drug Design, Development and Therapy. October 1st2013;7:1103-1113. Review. Full Text Link.

Evans, S. Gray, MA. Dowell, NG. [et al] (2013). APOE E4 Carriers show prospective memory enhancement under nicotine, and evidence for specialisation within medial BA10.Neuropsychopharmacology. March 2013;38(4):655-63. Full Text Link.

Meisler, MH. Grant, AE. Jones, JM. [et al] (2013). C9ORF72 expansion in a family with bipolar disorder. Bipolar Disorders. May2013;15(3):326-32. Full Text Link.

Wilcock, DM. Griffin, WS. (2013). Down's syndrome, neuroinflammation, and Alzheimer neuropathogenesis.Journal of Neuroinflammation. July 16th2013;10:84. Full Text Link.

Dobson-Stone, C. Luty, AA. Thompson, EM. [et al].Frontotemporal dementia-amyotrophic lateral sclerosis syndrome locus on chromosome 16p12.1-q12.2: genetic, clinical and neuropathological analysis.Acta Neuropathology. April 2013;125(4):523-33. Full Text Link.

Sabbagh, MN. Malek-Ahmadi, M. Dugger, BN. [et al].The influence of Apolipoprotein E genotype on regional pathology in Alzheimer's disease.BMC Neurology. May 11th2013;13:44. Full Text Link.

Lambert, JC. Ibrahim-Verbaas, CA. [and] Harold, D. [et al] (2013). Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease. Nature Genetics, Epub ahead of print: October 27th2013.

Goodall, EF. Heath, PR. Bandmann, O. [et al] (2013). Neuronal dark matter: the emerging role of microRNAs in neurodegeneration.Frontiers in Cellular Neuroscience. October 10th2013;7:178. Review. Full Text Link.

Ramanan, VK. Saykin, AJ. (2013). Pathways to neurodegeneration: mechanistic insights from GWAS in Alzheimer's disease, Parkinson's disease, and related disorders.American Journal of Neurodegenerative Disease. September 18th2013;2(3):145-175. Review. Full Text Link.

Kauwe, JS. Ridge, PG. Foster, NL. [et al] (2013). Strong evidence for a genetic contribution to late-onset Alzheimer's disease mortality: a population-based study. PLoS One. October 8th2013;8(10):e77087. Full Text Link.

Rayaprolu, S. Mullen, B. Baker, M. [et al] (2013).TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease.Molecular Neurodegeneration. June 21st2013;8:19. Full Text Link.

Hip Fracture

Zapatero, A. Barba, R. Canora, J. [et al] (2013). Hip fracture in hospitalized medical patients.BMC Musculoskeletal Disorders. January 8th2013;14:15. Full Text Link.

Tolppanen, AM. Lavikainen, P. Soininen, H. [et al] (2013). Incident hip fractures among community dwelling persons with Alzheimer's Disease in a Finnish nationwide register-based cohort. PLoS One. 2013;8(3):e59124. Full Text Link.

Kim, SD. Park, SJ. Lee, DH. [et al] (2013). Risk factors of morbidity and mortality following hip fracture surgery.Korean Journal of Anesthesiology. June 2013;64(6):505-10. Full Text Link.

HIV-Related

Spudich, S. (2013). HIV and neurocognitive dysfunction.Current HIV/AIDS Reports. September 2013;10(3):235-43. Review. Full Text Link.

Atashili, J. Gaynes, BN. Pence, BW. [et al] (2013). Prevalence, characteristics and correlates of a positive-dementia screen in patients on antiretroviral therapy in Bamenda, Cameroon: a cross-sectional study.BMC Neurology. July 15th2013;13:86. Full Text Link.

Imaging

Dickerson, BC. Wolk, DA.; Alzheimer's Disease Neuroimaging Initiative. Biomarker-based prediction of progression in MCI: Comparison of AD signature and hippocampal volume with spinal fluid amyloid-β and tau.Frontiers in Aging Neuroscience. October 11th2013;5:55. Full Text Link.

Premi, E. Gazzina, S. Bozzali, M. [et al].(2013). Cognitive reserve in granulin-related frontotemporal dementia: from preclinical to clinical stages. PLoS One. September 9th2013;8(9):e74762. Full Text Link.

Moretti, DV. Paternicò, D. Binetti, G. [et al] (2013). EEG upper/low alpha frequency power ratio relates to temporo-parietal brain atrophy and memory performances in mild cognitive impairment.Frontiers in Aging Neuroscience. October 25th2013;5:63. Full Text Link.

Braverman, ER. Blum, K. Damle, UJ. [et al] (2013). Evoked potentials and neuropsychological tests validate Positron Emission Topography (PET) brain metabolism in cognitively impaired patients. PLoS One. 2013;8(3):e55398. Full Text Link.

Kim, HJ. Kim, J. Cho, H. [et al] (2013).Individual subject classification of mixed dementia from pure subcortical vascular dementia based on subcortical shape analysis. PLoS One. October 10th2013;8(10):e75602. Full Text Link.

Foss, MP. Diniz, PR. Formigheri, P. [et al] (2013). Magnetic resonance imaging and neuropsychological testing in the spectrum of normal aging. Clinics. September 2013;68(9):1197-205. Full Text Link.

Zhang, Y. Wang, S. Ji, G. [et al] (2013). An MR brain images classifier system via particle swarm optimization and kernel support vector machine. ScientificWorldJournal. September 16th2013;130134. Full Text Link.

Garraux, G. Phillips, C. Schrouff, J. [et al] (2013). Multiclass classification of FDG PET scans for the distinction between Parkinson's disease and atypical parkinsonian syndromes.NeuroImage: Clinical. June 14th2013;2:883-93. Full Text Link.

Lambert, C. Lutti, A. Helms, G. [et al] (2013). Multiparametric brainstem segmentation using a modified multivariate mixture of Gaussians.NeuroImage: Clinical. May 16th2013;2:684-94. Full Text Link.

Wardlaw, JM. Smith, EE. Biessels, GJ. [et al]; STandards for ReportIng Vascular changes on nEuroimaging (STRIVE v1). (2013). Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration.Lancet Neurology. August 2013;12(8):822-38. Full Text Link.

Bagepally, BS. John, JP. Varghese, M. [et al] (2013).Relationship of clinical and cognitive variables with brain morphometric abnormalities in Alzheimer's disease: a voxel based morphometric study using 3-tesla MRI.Aging and Disease. October 1st2013;4(5):235-43. Full Text Link.

Barnes, J. Carmichael, OT. Leung, KK. [et al]; Alzheimer's Disease Neuroimaging Initiative. (2013). Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls.Neurobiology of Aging. August 2013;34(8):1996-2002. Full Text Link.

Mental Health

Sheehan, B. Lall, R. Gage, H. [et al] (2013). A 12-month follow-up study of people with dementia referred to general hospital liaison psychiatry services.Age and Ageing. November 2013;42(6):786-90.

Ferrari, AJ. Charlson, FJ. Norman, RE. [et al] (2013). Burden of depressive disorders by country, sex, age, and year: findings from the global burden of disease study 2010. PLoS Medicine. November 2013;10(11):e1001547.Full Text Link.

Bewernick, BH. Schlaepfer, TE. (2013). Chronic depression as a model disease for cerebral aging.Dialogues in Clinical Neurosciences. March 2013;15(1):77-85. Review. Full Text Link.

Luppa, M. Luck, T. Ritschel, F. [et al] (2013). Depression and incident dementia. An 8-year population-based prospective study. PLoS One. 2013;8(3):e59246. Full Text Link.

Kvelde, T. McVeigh, C. Toson, B. [et al] (2013). Depressive symptomatology as a risk factor for falls in older people: systematic review and meta-analysis.Journal of the American Geriatrics Society. May2013;61(5):694-706.

Underwood, M. Lamb, SE. Eldridge, S. [et al] (2013). Exercise for depression in care home residents: a randomised controlled trial with cost-effectiveness analysis (OPERA).Health Technology Assessments. May2013;17(18):1-281.

Underwood, M. Lamb, SE. Eldridge, S. [et al] (2013). Exercise for depression in elderly residents of care homes: a cluster-randomised controlled trial. Lancet. July 6th2013;382(9886):41-9. Full Text Link.

Stevens, E. (2013). The Mental Capacity Act 2005: considerations for nursing practice.Nursing Standard. September 11-17th2013;28(2):35-9.

Zvěřová, M. Fišar, Z. Jirák, R. [et al] (2013). Plasma cortisol in Alzheimer's disease with or without depressive symptoms.Medical Science Monitor. August 19th2013;19:681-9. Full Text Link.

Atkins, J. Naismith, SL. Luscombe, GM. [et al] (2013). A preliminary study of aged care facility staff indicates limitations in awareness of the link between depression and physical morbidity.BMC Geriatrics. April 9th2013;13:30. Full Text Link.

Almeida, OP. Pirkis, J. Kerse, N. [et al] (2013). A randomized trial to reduce the prevalence of depression and self-harm behavior in older primary care patients.Annals of Family Medicine. July - August 2012;10(4):347-56. Full Text Link.

Coupland, C. Morriss, R. Arthur, A. [et al] (2013). Safety of antidepressants in adults aged under 65: protocol for a cohort study using a large primary care database. BMC Psychiatry. May 10th2013;13:135. Full Text Link.

Leontjevas, R. Gerritsen, DL. Smalbrugge, M. [et al] (2013).A structural multidisciplinary approach to depression management in nursing-home residents: a multicentre, stepped-wedge cluster-randomised trial. Lancet. June 29th2013;381(9885):2255-64. Full Text Link.

McCabe, MP. Mellor, D. Davison, TE. [et al] (2013). A study protocol to investigate the management of depression and challenging behaviors associated with dementia in aged care settings.BMC Geriatrics. September 19th2013;13(1):95. [Epub ahead of print].Full Text Link.

Miscellaneous

Smith, GS (2013). Aging and neuroplasticity.Dialogues in Clinical Neurosciences. March 2013;15(1):3-5. Full Text Link.

Brouwer-Brolsma, EM. Feskens, EJ. Steegenga, WT. [et al] (2013). Associations of 25-hydroxyvitamin D with fasting glucose, fasting insulin, dementia and depression in European elderly: the SENECA study.European Journal of Nutrition. April 2013;52(3):917-25. Full Text Link.

Kuhlmann, A. Ólafsdóttir, IS. Lind, L. [et al] (2013). Association of biomarkers of inflammation and cell adhesion with lung function in the elderly: a population-based study.BMC Geriatrics. August 7th2013;13:82. Full Text Link.

Alladi, S. Bak, TH. [and] Duggirala, V. [et al] (2013). Bilingualism delays age at onset of dementia, independent of education and immigration status. Neurology, Published online November 6th2013.

Klein, D. Nagel, G. Kleiner, A. [et al] (2013). Blood pressure and falls in community-dwelling people aged 60 years and older in the VHM&PP cohort.BMC Geriatrics. May 21st2013;13:50. Full Text Link.

Porter, A. Mays, N. Shaw, SE. [et al] (2013). Commissioning healthcare for people with long term conditions: the persistence of relational contracting in England's NHS quasi-market.BMC Health Services Research. 2013;13 Supplement 1:S2. Full Text Link.

Gommans, J. Yi, Q. Eikelboom, JW. [et al] (2013). The effect of homocysteine-lowering with B-vitamins on osteoporotic fractures in patients with cerebrovascular disease: substudy of VITATOPS, a randomised placebo-controlled trial.BMC Geriatrics. September 3rd2013;13(1):88. [Epub ahead of print].Full Text Link.

Sullivan-Gunn, MJ. Lewandowski, PA. (2013). Elevated hydrogen peroxide and decreased catalase and glutathione peroxidase protection are associated with aging sarcopenia.BMC Geriatrics. October 7th2013;13(1):104. [Epub ahead of print].Full Text Link.

Cui, J. Shen, Y. Li, R. (2013). Estrogen synthesis and signaling pathways during aging: from periphery to brain.Trends in Molecular Medicine. March 2013;19(3):197-209. Review. Full Text Link.

Holznagel, E. Yutzy, B. Schulz-Schaeffer, W. [et al] (2013). Foodborne transmission of bovine spongiform encephalopathy to nonhuman primates.Emerging Infectious Diseases. May2013;19(5):712-20. Full Text Link.

Heaven, B. Bamford, C. May, C. [et al]. (2013). Food work and feeding assistance on hospital wards.Sociology of Health & Illness. May2013;35(4):628-42.

Daly, RM. Rosengren, BE. Alwis, G. [et al] (2013). Gender specific age-related changes in bone density, muscle strength and functional performance in the elderly: a-10 year prospective population-based study.BMC Geriatrics. July 6th2013;13(1):71. [Epub ahead of print].Full Text Link.

Dhurandhar, EJ. Allison, DB. van Groen, T. [et al] (2013). Hunger in the absence of caloric restriction improves cognition and attenuates Alzheimer's disease pathology in a mouse model. PLoS One. 2013;8(4):e60437. Full Text Link.

Appleby, BS. Lu, M. Bizzi, A. [et al] (2013). Iatrogenic Creutzfeldt-Jakob disease from commercial cadaveric human growth hormone.Emerging Infectious Diseases. April 2013;19(4):682-4. Full Text Link.

Hughes, LE. Rowe, JB. (2013). The impact of neurodegeneration on network connectivity: a study of change detection in frontotemporal dementia.Journal of Cognitive Neuroscience. May2013;25(5):802-13. Full Text Link.

Romero-Ortuno, R. O'Connell, MD. Finucane, C. [et al] (2013). Insights into the clinical management of the syndrome of supine hypertension - orthostatic hypotension (SH-OH): the Irish Longitudinal Study on Ageing (TILDA).BMC Geriatrics. July 15th2013;13:73. Full Text Link.

Morita, K. Kobayashi, M. (2013). Interactive programs with preschool children bring smiles and conversation to older adults: time-sampling study.BMC Geriatrics. October 18th2013;13(1):111. [Epub ahead of print].Full Text Link.

Bouillon, K. Kivimaki, M. Hamer, M. [et al] (2013). Measures of frailty in population-based studies: an overview.BMC Geriatrics. June 21st2013;13:64. Full Text Link.

Thomas, L. Little, L. Briggs, P. [et al] (2013). Location tracking: views from the older adult population.Age and Ageing. November 2013;42(6):758-63.

Jellinger, KA. Attems, J. (2013). Neuropathological approaches to cerebral aging and neuroplasticity.Dialogues in Clinical Neurosciences. March 2013;15(1):29-43. Review. Full Text Link.

Razlighi, QR. Stallard, E. Brandt, J. [et al] (2013). A new algorithm for predicting time to disease endpoints in Alzheimer's Disease patients.Journal of Alzheimer's Disease: JAD. September 24th2013. [Epub ahead of print].

Parker, SJ. Jessel, S. Richardson, JE. [et al] (2013). Older adults are mobile too!Identifying the barriers and facilitators to older adults' use of mHealth for pain management. BMC Geriatrics. May 6th2013;13:43. Full Text Link.

Zvěřová, M. Fišar, Z. Jirák, R. [et al] (2013). Plasma cortisol in Alzheimer's disease with or without depressive symptoms.Medical Science Monitor. August 19th2013;19:681-9. Full Text Link.

Badia, JG. Santos, AB. Segura, JC. [et al] (2013).Predictors of mortality among elderly dependent home care patients.BMC Health Services Research. August 15th2013;13(1):316. [Epub ahead of print].Full Text Link.

Legrand, D. Vaes, B. Matheï, C. [et al] (2013). The prevalence of sarcopenia in very old individuals according to the European consensus definition: insights from the BELFRAIL study.Age and Ageing. November 2013;42(6):727-34.

Ling, XW. Howe, TS. Koh, JS. [et al] (2013). Preoperative thyroid dysfunction predicts 30-day postoperative complications in elderly patients with hip fracture.Geriatric Orthopaedic Surgery and Rehabilitation. June 2013;4(2):43-9. Full Text Link.

de Moraes, SA. Soares, WJ. Ferriolli, E. [et al] (2013). Prevalence and correlates of dizziness in community-dwelling older people: a cross sectional population based study.BMC Geriatrics. January 4th2013;13:4. Full Text Link.

Hill, KM. Bara, AC. Davidson, S. [et al] (2013). Preventive cardiovascular care for older people: fundamental for healthy ageing?Age and Ageing. November 2013;42(6):675-6.

Ward, A. Tardiff, S. [and] Dye, C. [et al] (2013). Rate of conversion from prodromal Alzheimer’s disease to Alzheimer’s dementia: a systematic review of the literature. Dementia and Geriatric Cognitive Disorders Extra, September 28th2013, Vol.3(1), pp.320-32. Full Text Link.

Habell, M. (2013). Specialised design for dementia. Perspectives in Public Health. May2013;133(3):151-7.

Pugh, MJ. Marcum, ZA. Copeland, LA. [et al] (2013). The quality of quality measures: HEDIS® quality measures for medication management in the elderly and outcomes associated with new exposure.Drugs  & Aging. August 2013;30(8):645-54. Full Text Link.

Smith, AK. Lo, B. Sudore, R. (2013). When previously expressed wishes conflict with best interests.JAMA Internal Medicine. July 8th2013;173(13):1241-5. Full Text Link.

Neuroscientific / Neurological Research

George, S. Rey, NL. Reichenbach, N. [et al] (2013). α-Synuclein: the long distance runner.Brain Pathology. May2013;23(3):350-7. Review. Full Text Link.

Kaminsky, YG. Reddy, VP. Ashraf, GM. [et al] (2013).Age-related defects in erythrocyte 2,3-diphosphoglycerate metabolism in dementia.Aging and Disease. October 1st2013;4(5):244-55. Full Text Link.

Roostaee A, Beaudoin S, Staskevicius A, Roucou X. Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization.Molecular Neurodegeneration. January 22nd2013;8:5. Full Text Link.

Grolla, AA. Sim, JA. Lim, D. [et al] (2013). Amyloid-β and Alzheimer's disease type pathology differentially affects the calcium signalling toolkit in astrocytes from different brain regions.Cell Death and Disease. May 9th2013;4:e623. Full Text Link.

Goncalves, MB. Clarke, E. Hobbs, C. [et al] (2013).Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist.European Journal of Neuroscience. April 2013;37(7):1182-92. Full Text Link.

Gordon, PH (2013). Amyotrophic Lateral Sclerosis: an update for 2013 Clinical Features, Pathophysiology, Management and Therapeutic Trials.Aging and Disease. October 1st2013;4(5):295-310. Review. Full Text Link.

Liraz, O. Boehm-Cagan, A.[and] Michaelson, DM. (2013). ApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.Molecular Neurodegeneration. May 17th2013;8:16. Full Text Link.

Li, W. Tang, Y. Fan, Z. [et al].Autophagy is involved in oligodendroglial precursor-mediated clearance of amyloid peptide.Molecular Neurodegeneration. August 10th2013;8:27. Full Text Link.

Rajagopalan, V. Liu, Z. Allexandre, D. [et al] (2013) .Brain white matter shape changes in Amyotrophic Lateral Sclerosis (ALS): a fractal dimension study. PLoS One. September 9th2013;8(9):e73614. Full Text Link.

Chapman, RM. Porsteinsson, AP. Gardner, MN. [et al] (2013). C145 as a short-latency electrophysiological index of cognitive compensation in Alzheimer's Disease.Journal of Alzheimer's Disease: JAD. 2013;33(1):55-68. Full Text Link.

Landqvist Waldö, M. Frizell Santillo, A. Passant, U. [et al] (2013). Cerebrospinal fluid neurofilament light chain protein levels in subtypes of frontotemporal dementia.BMC Neurology. May 29th2013;13:54. Full Text Link.

McCarter, JF. Liebscher, S. Bachhuber, T. [et al] (2013). Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer's disease.Acta Neuropathology. August 2013;126(2):179-88. Full Text Link.

Negash, S. Xie, S. Davatzikos, C. [et al] (2013). Cognitive and functional resilience despite molecular evidence of Alzheimer's disease pathology.Alzheimer's & Dementia: the Journal of the Alzheimer's Association. May2013;9(3):e89-95. Full Text Link.

Farlow, MR. Schmitt, F. Aarsland, D. [et al] (2013). Comparing clinical profiles in Alzheimer's disease and Parkinson's disease dementia.Dementia and Geriatric Cognitive Disisorders Extra. September 11th2013;3(1):281-90. Full Text Link.

Fonseca, MI. McGuire, SO. Counts, SE. [et al] (2013). Complement activation fragment C5a receptors, CD88 and C5L2, are associated with neurofibrillary pathology.Journal of Neuroinflammation. February 8th2013;10:25. Full Text Link.

Kandimalla, RJ. Prabhakar, S. Wani, WY. [et al] (2013). CSF p-Tau levels in the prediction of Alzheimer's disease. Biology Open. September 4th 2013; 2(11): 1119-24. Full Text Link.

Devi, L. Ohno, M. (2013). Deletion of the eIF2α kinase GCN2 fails to rescue the memory decline associated with Alzheimer's Disease. PLoS One. October 11th2013;8(10):e77335. Full Text Link.

Yi, BR. Kim, SU. Choi, KC. (2013). Development and application of neural stem cells for treating various human neurological diseases in animal models.Laboratory Animal Research. September 2013;29(3):131-137. Review. Full Text Link.

Parent, M. Bédard, C. Pourcher, E. (2013). Dopaminergic innervation of the human subventricular zone: a comparison between Huntington's chorea and Parkinson's disease.American Journal of Neurodegenerative Disease. September 18th2013;2(3):221-7. Full Text Link.

Wilcock, DM. Griffin, WS. (2013). Down's syndrome, neuroinflammation, and Alzheimer neuropathogenesis.Journal of Neuroinflammation. July16th2013;10:84. Full Text Link.

Cui, J. Shen, Y. Li, R. (2013). Estrogen synthesis and signaling pathways during aging: from periphery to brain.Trends in Molecular Medicine. March 2013;19(3):197-209. Review. Full Text Link.

Michel, CH. Kumar, S. [and] Pinotsi, D. [et al] (2013). Extracellular monomeric Tau is sufficient to initiate the spread of Tau pathology. The Journal of Biological Chemistry, November 14th2013, [Epub ahead of print]. Full Text Link.

Kam, TI. Song, S. Gwon, Y. [et al].FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease.Journal of Clinical Investigation. July 1st2013;123(7):2791-802. Full Text Link.

Rosén, C. Hansson, O. Blennow, K. [et al] (2013).Fluid biomarkers in Alzheimer's disease: current concepts.Molecular Neurodegeneration. June 21st2013;8:20. Full Text Link.

Chen, KC. Blalock, EM. Curran-Rauhut, MA. [et al] (2013). Glucocorticoid-dependent hippocampal transcriptome in male rats: pathway-specific alterations with aging. Endocrinology. August 2013;154(8):2807-20. Full Text Link.

Xiao, X. Yuan, J. Haïk, S. [et al] (2013). Glycoform-selective prion formation in sporadic and familial forms of prion disease. PLoS One. 2013;8(3):e58786. Full Text Link.

Natale, G. Pompili, E. Biagioni, F. [et al] (2013). Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases.European Journal of Histochemistry: EJH. March 7th2013;57(1):e5. Review. Full Text Link.

Appleby, BS. Lu, M. Bizzi, A. [et al] (2013). Iatrogenic Creutzfeldt-Jakob disease from commercial cadaveric human growth hormone.Emerging Infectious Diseases. April 2013;19(4):682-4. Full Text Link.

Brito, V. Puigdellívol, M. Giralt, A. [et al] (2013). Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies.Cell Death and Disease. April 18th2013;4:e595. Full Text Link.

Lombino, F. Biundo, F. Tamayev, R. [et al] (2013). An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss. PLoS One. 2013;8(2):e57120. Full Text Link.

Ulrich, JD. Burchett, JM. Restivo, JL. [et al] (2013). In vivo measurement of apolipoprotein E from the brain interstitial fluid using microdialysis.Molecular Neurodegeneration. April 19th2013 ;8:13. 10.Full Text Link.

Francolini, M. Sicurella, L. Rizzuto, N. (2013). Leptomeningeal carcinomatosis mimicking Creutzfeldt-Jakob disease: clinical features, laboratory tests, MRI images, EEG findings in an autopsy-proven case. Neurological Sciences. April 2013;34(4):441-4. Full Text Link.

Wang, M. Turko, IV. (2013). Mass spectrometry quantification revealed accumulation of C-terminal fragment of apolipoprotein E in the Alzheimer's frontal cortex. PLoS One. April 11th2013;8(4):e61498. Full Text Link.

Yan, MH. Wang, X. Zhu, X. (2013). Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease.Journal of Free Radicals in Biology & Medicine. September 2013;62:90-101. Full Text Link.

Hellstrand, E. Nowacka, A. Topgaard, D. [et al] (2013). Membrane lipid co-aggregation with α-synuclein fibrils. PLoS One. October 11th2013;8(10):e77235. Full Text Link.

Mitew, S. Kirkcaldie, MT. Dickson, TC. [et al] (2013).Neurites containing the neurofilament-triplet proteins are selectively vulnerable to cytoskeletal pathology in Alzheimer's disease and transgenic mouse models.Frontiers in Neuroanatomy. September 26th2013;7:30. Full Text Link.

Sanchez-Guajardo, V. Barnum, CJ. Tansey, MG. [et al] (2013). Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity. ASN Neuro. April 30th2013;5(2):113-39. Full Text Link.

Wright, AL. Zinn, R. Hohensinn, B. [et al] (2013). Neuroinflammation and neuronal loss precede Aβ plaque deposition in the hAPP-J20 mouse model of Alzheimer's disease. PLoS One. 2013;8(4):e59586. Full Text Link.

Jellinger, KA. Attems, J. (2013). Neuropathological approaches to cerebral aging and neuroplasticity.Dialogues in Clinical Neurosciences. March 2013;15(1):29-43. Review. Full Text Link.

Posadas, I. López-Hernández, B. Ceña, V. (2013). Nicotinic receptors in neurodegeneration.Current Neuropharmacology. May2013;11(3):298-314. Full Text Link.

Dunlop, RA. Cox, PA. Banack, SA. [et al].The non-protein amino acid BMAA is misincorporated into human proteins in place of l-Serine causing protein misfolding and aggregation. PLoS One. September 25th2013;8(9):e75376. Full Text Link.

Bouter, Y. Dietrich, K. Wittnam, JL. [et al] (2013). N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits.Acta Neuropathology. August 2013;126(2):189-205. Full Text Link.

Kim, J. Chakrabarty, P. Hanna, A. [et al] (2013). Normal cognition in transgenic BRI2-Aβ mice.Molecular Neurodegeneration. May 12th2013;8:15. Full Text Link.

Wang, H. Ren, CH. Gunawardana, CG. [et al] (2013).Overcoming barriers and thresholds: signaling of oligomeric Aβ through the prion protein to Fyn.Molecular Neurodegeneration. July 16th2013;8:24. Review. Full Text Link.

Ozdemir, AY. Rom, I. Kovalevich, J. [et al]. (2013). PINCH in the cellular stress response to tau-hyperphosphorylation. PLoS One. 2013;8(3):e58232. Full Text Link.

Ismail, MF. Elmeshad, AN. Salem, NA. (2013). Potential therapeutic effect of nanobased formulation of rivastigmine on rat model of Alzheimer's disease.International Journal of Nanomedicine. 2013;8:393-406. Full Text Link.

Bagepally, BS. John, JP. Varghese, M. [et al] (2013).Relationship of clinical and cognitive variables with brain morphometric abnormalities in Alzheimer's disease: a voxel based morphometric study using 3-tesla MRI.Aging and Disease. October 1st2013;4(5):235-43. Full Text Link.

Olde Dubbelink, KT. Stoffers, D. Deijen, JB. [et al] (2013). Resting-state functional connectivity as a marker of disease progression in Parkinson's disease: a longitudinal MEG study.NeuroImage: Clinical. April 11th2013;2:612-9. Full Text Link.

Hayes, CD. Dey, D. Palavicini, JP. [et al] (2013). Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine.BMC Medicine. March 26th2013;11:81. Full Text Link.

Halliez, S. Chesnais, N. [and] Mallucci, GR. [et al] (2013). Targeted knock-down of cellular prion protein expression in myelinating Schwann cells does not alter mouse prion pathogenesis. Journal of General Virology. June 2013; 94(Pt 6): 1435-40.

Halliday M, Mallucci GR. Targeting the unfolded protein response in neurodegeneration: A new approach to therapy. Neuropharmacology. January 2014;76(Pt A):169-74.

LaClair, KD. Manaye, KF. Lee, DL. [et al] (2013).Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice.Molecular Neurodegeneration. June 13th2013;8:18. Full Text Link.

Religa, P. Cao, R. Religa, D. [et al] (2013). VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival.Scientific Reports. 2013;3:2053. Full Text Link.

Kuruppu, DK. Matthews, BR. (2013). Young-onset dementia. Seminars in Neurology. September 2013; 33(4): 365-85.

Non-Pharmacological Treatments

Trueland, J. (2013). Bring back memories. Nursing Standard. February 27th – March 5th2013;27(26):16-8. Full Text Link.

Bahar-Fuchs, A. Clare, L. [and] Woods, B. (2013). Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer’s disease and vascular dementia. Cochrane Database of Systematic Reviews (Online). June 5th2013; Issue 6: No. CD003260. Full Text Link.

Yi, BR. Kim, SU. Choi, KC. (2013). Development and application of neural stem cells for treating various human neurological diseases in animal models.Laboratory Animal Research. September 2013;29(3):131-137. Review. Full Text Link.

Clare, L. Bayer, A. Burns, A. [et al] (2013). Goal-oriented cognitive rehabilitation in early-stage dementia: study protocol for a multi-centre single-blind randomised controlled trial (GREAT). Trials. May 27th2013;14:152. Full Text Link.

Brilleman, SL. Purdy, S. Salisbury, C. [et al] (2013). Implications of comorbidity for primary care costs in the UK: a retrospective observational study.British Journal of General Practice. April 2013;63(609):e274-82.

Bredesen, DE. John, V. (2013). Next generation therapeutics for Alzheimer's disease.EMBO Molecular Medicine. June 2013;5(6):795-8. Full Text Link.

Gitlin, LN. Mann, WC. Vogel, WB. [et al] (2013). A non-pharmacologic approach to address challenging behaviors of veterans with dementia: description of the tailored activity program-VA randomized trial.BMC Geriatrics. 2013 September 23rd;13(1):96. [Epub ahead of print].Full Text Link.

Slaughter, SE. Estabrooks, CA. (2013). Optimizing the mobility of residents with dementia: a pilot study promoting healthcare aide uptake of a simple mobility innovation in diverse nursing home settings.BMC Geriatrics. October 18th2013;13(1):110. [Epub ahead of print].Full Text Link.

Fu, CY. Moyle, W. Cooke, M. (2013). A randomised controlled trial of the use of aromatherapy and hand massage to reduce disruptive behaviour in people with dementia.BMC Complementary and Alternative Medicine. July 10th2013;13:165. Full Text Link.

Parkinson’s Disease

George, S. Rey, NL. Reichenbach, N. [et al] (2013). α-Synuclein: the long distance runner. Brain Pathology. May2013;23(3):350-7. Review. Full Text Link.

Ma, L. Wei, L. Wu, F. [et al] (2013). Advances with microRNAs in Parkinson's disease research. Drug Design, Development and Therapy. October 1st2013;7:1103-1113. Review. Full Text Link.

Farlow, MR. Schmitt, F. Aarsland, D. [et al] (2013). Comparing clinical profiles in Alzheimer's disease and Parkinson's disease dementia. Dementia and Geriatric Cognitive Disorders Extra. September 11th2013;3(1):281-90. Full Text Link.

Volpe, D. Signorini, M. Marchetto, A. [et al] (2013). A comparison of Irish set dancing and exercises for people with Parkinson's disease: a phase II feasibility study.BMC Geriatrics. June 4th2013;13:54. Full Text Link.

Macdonald, AA. Seergobin, KN. Owen, AM. [et al] (2013).Differential effects of Parkinson's Disease and dopamine replacement on memory encoding and retrieval. PLoS One. September 26th2013;8(9):e74044. Full Text Link.

Swift, T. Huxtable, R. (2013). The ethics of sham surgery in Parkinson's disease: back to the future? Bioethics. May2013;27(4):175-85. Full Text Link.

Kim, HY. Chang, WS. Kang, DW. [et al] (2013). Factors related to outcomes of subthalamic deep brain stimulation in Parkinson's disease.Journal of Korean Neurosurgical Society. August 2013;54(2):118-24. Full Text Link.

Inamdar, AA. Hossain, MM. [and] Bernstein, AI. [et al] (2013). Fungal-derived semiochemical 1-octen-3-ol disrupts dopamine packaging and causes neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America, November 11th 2013. [Epub ahead of print].

Mazzio, E. Deiab, S. Park, K. [et al] (2013). High throughput screening to identify natural human monoamine oxidase B inhibitors.Phytotherapy Research: PTR. June 2013;27(6):818-28. Full Text Link.

Dietz, J. Bradley, MM. Jones, J. [et al] (2013). The late positive potential, emotion and apathy in Parkinson's disease. Neuropsychologia. April 2013;51(5):960-6. Full Text Link.

Yan, MH. Wang, X. Zhu, X. (2013). Mitochondrial defects and oxidative stress in Alzheimer disease and Parkinson disease.Journal of Free Radicals in Biology & Medicine. September 2013;62:90-101. Full Text Link.

Avanzino, L. Pelosin, E. Martino, D. [et al] (2013).Motor timing deficits in sequential movements in Parkinson disease are related to action planning: a motor imagery study. PLoS One. September 23rd2013;8(9):e75454. Full Text Link.

Garraux, G. Phillips, C. Schrouff, J. [et al] (2013). Multiclass classification of FDG PET scans for the distinction between Parkinson's disease and atypical parkinsonian syndromes.NeuroImage: Clinical. June 14th2013;2:883-93. Full Text Link.

Sanchez-Guajardo, V. Barnum, CJ. Tansey, MG. [et al] (2013). Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity. ASN Neuro. April 30th2013;5(2):113-39. Full Text Link.

Breen, KC. Drutyte, G. (2013). Non-motor symptoms of Parkinson's disease: the patient's perspective.Journal of Neural Transmission. April 2013            ;120(4):531-5. Full Text Link.

Cummings, J. Isaacson, S. [and] Mills, R. [et al] (2013). Pimavanserin for patients with Parkinson’s disease psychosis: a randomised, placebo-controlled phase 3 trial. Lancet, October 31st2013, [Epub ahead of print]. Full Text Link.

Wei, Q. Wang, H. Tian, Y. [et al] (2013).Reduced serum levels of triglyceride, very low density lipoprotein cholesterol and apolipoprotein B in Parkinson's disease patients. PLoS One. September 26th2013;8(9):e75743. Full Text Link.

Fereshtehnejad, SM. Hadizadeh, H. Farhadi, F. [et al]. (2013). Reliability and validity of the persian version of the fatigue severity scale in idiopathic Parkinson's disease patients.Parkinsons Disease. 2013;935429. Full Text Link.

Olde Dubbelink, KT. Stoffers, D. Deijen, JB. [et al] (2013). Resting-state functional connectivity as a marker of disease progression in Parkinson's disease: a longitudinal MEG study.NeuroImage: Clinical. April 11th2013;2:612-9. Full Text Link.

Shine, JM. Moustafa, AA. Matar, E. [et al] (2013). The role of frontostriatal impairment in freezing of gait in Parkinson's disease.Frontiers in Systems Neuroscience. October 4th2013;7:61. Full Text Link.

Maass, A. Reichmann, H. (2013). Sleep and non-motor symptoms in Parkinson's disease.Journal of Neural Transmission. April 2013;120(4):565-9. Full Text Link.

Ossig, C. Reichmann, H. (2013). Treatment of Parkinson's disease in the advanced stage.Journal of Neural Transmission. April 2013;120(4):523-9. Full Text Link.

Baram, Y. (2013). Virtual sensory feedback for gait improvement in neurological patients.Frontiers in Neurology. October 14th2013;4:138. Review. Full Text Link.

Pharmacological Treatments

Lambracht-Washington, D. Rosenberg, RN. (2013). Advances in the development of vaccines for Alzheimer's disease.Discovery Medicine. May2013;15(84):319-26. Full Text Link.

Jenkins, C. McKay, A. (2013). A collaborative approach to health promotion in early stage dementia.Nursing Standard. May 8-14th2013;27(36):49-57; quiz 58. Full Text Link.

Jenkins, C. McKay, A. (2013). Collaborative health promotion in middle and later stages of dementia.Nursing Standard. May 15-21st2013;27(37):49-56; quiz 58, 60. Full Text Link.

Kapoor, S. (2013). Comment on "Berberine and its emerging benefits in psychiatric conditions especially Alzheimer's disease". ScientificWorldJournal. April 28th2013;612684. Full Text Link.

Kuehn, BM. (2013). Efforts stall to curb nursing home antipsychotic use. JAMA. September 18th2013;310(11):1109-10.

de Vries, OJ. Peeters, G. Elders, P. [et al] (2013). The elimination half-life of benzodiazepines and fall risk: two prospective observational studies.Age and Ageing. November 2013;42(6):764-70.

Mazzio, E. Deiab, S. Park, K. [et al] (2013). High throughput screening to identify natural human monoamine oxidase B inhibitors.Phytotherapy Research: PTR. June 2013;27(6):818-28. Full Text Link.

Chan, FW. Wong, FY. So, WY. [et al] (2013). How much do elders with chronic conditions know about their medications?BMC Geriatrics. June 13th2013;13:59. Full Text Link.

Campbell, NL. Dexter, P. Perkins, AJ. [et al] (2013). Medication adherence and tolerability of Alzheimer's disease medications: study protocol for a randomized controlled trial. Trials. May 4th2013;14:125. Full Text Link.

Bredesen, DE. John, V. (2013). Next generation therapeutics for Alzheimer's disease.EMBO Molecular Medicine. June 2013;5(6):795-8. Full Text Link.

Maxwell, CJ. Vu, M. Hogan, DB. [et al] (2013). Patterns and determinants of dementia pharmacotherapy in a population-based cohort of home care clients.Drugs  & Aging. July 2013;30(7):569-85.

Chollet, F. (2013). Pharmacologic approaches to cerebral aging and neuroplasticity: insights from the stroke model.Dialogues in Clinical Neurosciences. March 2013;15(1):67-76. Review. Full Text Link.

Cummings, J. Isaacson, S. [and] Mills, R. [et al] (2013). Pimavanserin for patients with Parkinson’s disease psychosis: a randomised, placebo-controlled phase 3 trial. Lancet, October 31st 2013, [Epub ahead of print]. Full Text Link.

Brewer, L. Bennett, K. McGreevy, C. [et al] (2013). A population-based study of dosing and persistence with anti-dementia medications.European Journal of Clinical Pharmacology. July 2013;69(7):1467-75.

Araki, W. (2013).Potential repurposing of oncology drugs for the treatment of Alzheimer's disease.BMC Medicine. March 26th2013;11:82. Full Text Link.

Montastruc, F. Gardette, V. Cantet, C. [et al]; REAL.FR Group. (2013). Potentially inappropriate medication use among patients with Alzheimer disease in the REAL.FR cohort: be aware of atropinic and benzodiazepine drugs!European Journal of Clinical Pharmacology. August 2013;69(8):1589-97.

Schulze, J. Glaeske, G. van den Bussche, H. [et al] (2013). Prescribing of antipsychotic drugs in patients with dementia: a comparison with age-matched and sex-matched non-demented controls.Pharmacoepidemiology and Drug Safety. December 2013;22(12):1308-16.

Kashyap, M. Tu, LM. Tannenbaum, C. (2013). Prevalence of commonly prescribed medications potentially contributing to urinary symptoms in a cohort of older patients seeking care for incontinence.BMC Geriatrics. June 10th2013;13(1):57. [Epub ahead of print].Full Text Link.

Sun, P. Chen, JY. Li, J. [et al] (2013).The protective effect of geniposide on human neuroblastoma cells in the presence of formaldehyde.BMC Complementary and Alternative Medicine. July 1st2013;13:152. Full Text Link.

Gustafsson, M. Karlsson, S. Gustafson, Y. (2013). Psychotropic drug use among people with dementia -- a six-month follow-up study. BMC Pharmacologyand Toxicology. November 7th2013;14(1):56. [Epub ahead of print]. Full Text Link.

Pugh, MJ. Marcum, ZA. Copeland, LA. [et al] (2013). The quality of quality measures: HEDIS® quality measures for medication management in the elderly and outcomes associated with new exposure.Drugs  & Aging. August 2013;30(8):645-54. Full Text Link.

Coupland, C. Morriss, R. Arthur, A. [et al] (2013). Safety of antidepressants in adults aged under 65: protocol for a cohort study using a large primary care database. BMC Psychiatry. May 10th2013;13:135. Full Text Link.

Ossig, C. Reichmann, H. (2013). Treatment of Parkinson's disease in the advanced stage.Journal of Neural Transmission. April 2013;120(4):523-9. Full Text Link.

Quality of Life

Hazzan, AA. Ploeg, J. Shannon, H. [et al] (2013). Association between caregiver quality of life and the care provided to persons with Alzheimer's disease: protocol for a systematic review. Syst Rev. March 13th2013;2:17. Review. Full Text Link.

Knott, CS. Scholes, S. Shelton, NJ. (2013). Could more than three million older people in England be at risk of alcohol-related harm? A cross-sectional analysis of proposed age-specific drinking limits.Age and Ageing. September 2013;42(5):598-603.

Vreeken, HL. van Rens, GH. Kramer, SE. [et al] (2013). Dual sensory loss: development of a dual sensory loss protocol and design of a randomized controlled trial.BMC Geriatrics. August 13th2013;13:84. Full Text Link.

Halek, M. Dichter, MN. Quasdorf, T. [et al] (2013). The effects of dementia care mapping on nursing home residents' quality of life and staff attitudes: design of the quasi-experimental study Leben-QD II.BMC Geriatrics. June 1st2013;13:53. Full Text Link.

Edmans, J. Bradshaw, L. Gladman, JR. [et al] (2013). The Identification of Seniors at Risk (ISAR) score to predict clinical outcomes and health service costs in older people discharged from UK acute medical units.Age and Ageing. November 2013;42(6):747-53. Full Text Link.

Thomas, L. Little, L. Briggs, P. [et al] (2013). Location tracking: views from the older adult population.Age and Ageing. November 2013;42(6):758-63.

Howlett, SE. Rockwood, K. (2013). New horizons in frailty: ageing and the deficit-scaling problem.Age and Ageing. July 2013;42(4):416-23.

Chen, L. Nelson, DR. Zhao, Y. [et al] (2013). Relationship between muscle mass and muscle strength, and the impact of comorbidities: a population-based, cross-sectional study of older adults in the United States.BMC Geriatrics. July 16th2013;13(1):74. [Epub ahead of print].Full Text Link.

McCarthy, VL. Ling, J. Carini, RM. (2013). The role of self-transcendence: a missing variable in the pursuit of successful aging?Research in Gerontological  Nursing. July 2013;6(3):178-86. 

Boyle, G. (2013). 'She's usually quicker than the calculator': financial management and decision-making in couples living with dementia.Health and Social Care in the Community. September 2013;21(5):554-62.

Ramlagan, S. Peltzer, K. Phaswana-Mafuya, N. (2013). Social capital and health among older adults in South Africa.BMC Geriatrics. September 28th2013;13(1):100. [Epub ahead of print].Full Text Link.

Agahi, N. Lennartsson, C. Kåreholt, I. [et al] (2013). Trajectories of social activities from middle age to old age and late-life disability: a 36-year follow-up.Age and Ageing. November 2013;42(6):790-3.

Bakker, C. de Vugt, ME. van Vliet, D. [et al](2013). Unmet needs and health-related quality of life in young-onset dementia.The American Journal of Geriatric Psychiatry. July 17th2013.

Körner, S. Hendricks, M. Kollewe, K. [et al] (2013). Weight loss, dysphagia and supplement intake in patients with amyotrophic lateral sclerosis (ALS): impact on quality of life and therapeutic options.BMC Neurology. July 12th2013;13:84. Full Text Link.

Rehabilitation

Sakurai, R. Fujiwara, Y. Ishihara, M. [et al] (2013). Age-related self-overestimation of step-over ability in healthy older adults and its relationship to fall risk.BMC Geriatrics. May 7th2013;13:44. Full Text Link.

Treacy, D. Sherrington, C. Schurr, K. (2013). Balance circuit classes to improve balance among rehabilitation inpatients: a protocol for a randomised controlled trial.BMC Geriatrics. July 20th2013;13(1):75. [Epub ahead of print].Full Text Link.

Gschwind, YJ. Kressig, RW. Lacroix, A. [et al] (2013). A best practice fall prevention exercise program to improve balance, strength / power, and psychosocial health in older adults: study protocol for a randomized controlled trial.October 9th2013;13(1):105. [Epub ahead of print.Full Text Link.

Drza-Grabiec, J. Snela, SA. Ryka A, J. [et al] (2013). Changes in the body posture of women occurring with age.BMC Geriatrics. October 12th2013;13(1):108. [Epub ahead of print].Full Text Link.

Vreeken, HL. van Rens, GH. Kramer, SE. [et al] (2013). Dual sensory loss: development of a dual sensory loss protocol and design of a randomized controlled trial.BMC Geriatrics. August 13th2013;13:84. Full Text Link.

Crocker, T. Young, J. Forster, A. [et al] (2013). The effect of physical rehabilitation on activities of daily living in older residents of long-term care facilities: systematic review with meta-analysis.Age and Ageing. November 2013;42(6):682-8.

Dal Bello-Haas, VP. Thorpe, LU. Lix, LM. [et al] (2013). The effects of a long-term care walking program on balance, falls and well-being.BMC Geriatrics. December 18th2012;12:76. Full Text Link.

Kosse, NM. Dutmer, AL. Dasenbrock, L. [et al] (2013). Effectiveness and feasibility of early physical rehabilitation programs for geriatric hospitalized patients: a systematic review.BMC Geriatrics. October 10th2013;13(1):107. [Epub ahead of print].Full Text Link.

Dal Bello-Haas, VP. Thorpe, LU. Lix, LM. [et al] (2013). The effects of a long-term care walking program on balance, falls and well-being.BMC Geriatrics. December 18th2012;12:76. Full Text Link.

Logue, MD. Drago, J. (2013). Evaluation of a modified community based care transitions model to reduce costs and improve outcomes.BMC Geriatrics. September 12th2013;13(1):94. [Epub ahead of print.Full Text Link.

Sachdev, PS. Lipnicki, DM. Crawford, J. [et al]; Sydney Memory, Ageing Study Team (2013). Factors predicting reversion from mild cognitive impairment to normal cognitive functioning: a population-based study. PLoS One. 2013;8(3):e59649. Full Text Link.

Kwok, BC. Pua, YH. Mamun, K. [et al] (2013). The minimal clinically important difference of six-minute walk in Asian older adults.BMC Geriatrics. March 6th2013;13:23. Full Text Link.

Eklund, K. Wilhelmson, K. Gustafsson, H. [et al] (2013). One-year outcome of frailty indicators and activities of daily living following the randomised controlled trial; "Continuum of care for frail older people".BMC Geriatrics. July 22nd2013;13(1):76. [Epub ahead of print].Full Text Link.

Slaughter, SE. Estabrooks, CA. (2013). Optimizing the mobility of residents with dementia: a pilot study promoting healthcare aide uptake of a simple mobility innovation in diverse nursing home settings.BMC Geriatrics. October 18th2013;13(1):110. [Epub ahead of print].Full Text Link.

Research & Methodology

Charlesworth, G. Burnell, K. Hoe, J. [et al] (2013).Acceptance checklist for clinical effectiveness pilot trials: a systematic approach.BMC Medical Research Methodology. June 13th2013;13:78. Full Text Link.

Guaita, A. Colombo, M. Vaccaro, R. [et al] (2013). Brain aging and dementia during the transition from late adulthood to old age: design and methodology of the "Invece.Ab" population-based study.BMC Geriatrics. September 24th2013;13(1):98. [Epub ahead of print].Full Text Link.

Swift, T. Huxtable, R. (2013). The ethics of sham surgery in Parkinson's disease: back to the future? Bioethics. May2013;27(4):175-85. Full Text Link.

Higgins, P. (2013).Involving people with dementia in research. Nursing Times. 2013 July 17-23;109(28):20-3. Full Text Link.

Stevens, Z. Carpenter, H. Gawler, S. [et al]; ProAct65+ Team (2013). Lessons learnt during a complex, multicentre cluster randomised controlled trial: the ProAct65+ trial. Trials. July 1st2013;14:192. Full Text Link.

D'Angelo, GM. Luo, J. Xiong, C. (2013). Missing data methods for partial correlations.Journal of Biometrics and Biostatistics. December 2012;3(8). Full Text Link.

Goodall, EF. Heath, PR. Bandmann, O. [et al] (2013). Neuronal dark matter: the emerging role of microRNAs in neurodegeneration.Frontiers in Cellular Neuroscience. October 10th2013;7:178. Review. Full Text Link.

Wilkes, S. Pearce, S. Ryan, V. [et al] (2013). Study of Optimal Replacement of Thyroxine in the ElDerly (SORTED): protocol for a mixed methods feasibility study to assess the clinical utility of lower dose thyroxine in elderly hypothyroid patients: study protocol for a randomized controlled trial. Trials. March 22nd2013;14:83. Full Text Link.

McCabe, MP. Mellor, D. Davison, TE. [et al] (2013). A study protocol to investigate the management of depression and challenging behaviors associated with dementia in aged care settings.BMC Geriatrics. September 19th2013;13(1):95. [Epub ahead of print].Full Text Link.

Stroke-Related

Wong, GK. Lam, SW. Ngai, K. [et al]. (2013). Cognitive domain deficits in patients with aneurysmal subarachnoid haemorrhage at 1 year.Journal of Neurology, Neurosurgery, and Psychiatry. September 2013;84(9):1054-8. Full Text Link.

Visser, MM. Heijenbrok-Kal, MH. van 't Spijker, A. [et al] (2013). The effectiveness of problem solving therapy for stroke patients: study protocol for a pragmatic randomized controlled trial.BMC Neurology. June 27th2013;13:67. Full Text Link.

Brauer, SG. Hayward, KS. Carson, RG. [et al] (2013). The efficacy of SMART Arm training early after stroke for stroke survivors with severe upper limb disability: a protocol for a randomised controlled trial.BMC Neurology. July 2nd2013;13:71. Full Text Link.

Tansy, AP. Liebeskind, DS. (2013). The Goldilocks dilemma in acute ischemic stroke. Frontiers in Neurology. October 21st2013;4:164. Review. Full Text Link.

Sunnerhagen, KS. Danielsson, A. Rafsten, L. [et al] (2013). Gothenburg very early supported discharge study (GOTVED) NCT01622205: a block randomized trial with superiority design of very early supported discharge for patients with stroke.BMC Neurology. June 24th2013;13:66. Full Text Link.

Khan, NA. Quan, H. Hill, MD. [et al] (2013). Risk factors, quality of care and prognosis in South Asian, East Asian and White patients with stroke.BMC Neurology. July 5th2013;13:74. Full Text Link.

Shigematsu, K. Nakano, H. Watanabe, Y. [et al] (2013). Speech disturbance at stroke onset is correlated with stroke early mortality.BMC Neurology. July 15th2013;13:87. Full Text Link.

Mavaddat, N. Savva, GM. Lasserson, DS. [et al] (2013). Transient neurological symptoms in the older population: report of a prospective cohort study - the Medical Research Council Cognitive Function and Ageing Study (CFAS). BMJ Open. July 24th2013;3(7). Full Text Link.

Rahbar, MH. Gonzales, NR. Ardjomand-Hessabi, M. [et al] (2013). The University of Texas Houston Stroke Registry (UTHSR): implementation of enhanced data quality assurance procedures improves data quality.BMC Neurology. June 15th2013;13:61. Full Text Link.

Vascular Dementia

Bahar-Fuchs A, Clare L, Woods B. (2013). Cognitive training and cognitive rehabilitation for persons with mild to moderate dementia of the Alzheimer’s or vascular type: a review. Alzheimer’s Research & Therapy. August 7th2013; 5(4): 35. [Epub ahead of print].

Kim, HJ. Kim, J. Cho, H. [et al] (2013).Individual subject classification of mixed dementia from pure subcortical vascular dementia based on subcortical shape analysis. PLoS One. October 10th2013;8(10):e75602. Full Text Link.

Wardlaw, JM. Smith, EE. Biessels, GJ. [et al]; STandards for ReportIng Vascular changes on nEuroimaging (STRIVE v1). (2013). Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration.Lancet Neurology. August 2013;12(8):822-38. Full Text Link.

Connolly, A. Campbell, S. Gaehl, E. [et al] (2013). Under-provision of medical care for vascular diseases for people with dementia in primary care: a cross-sectional review.British Journal of General Practice. February 2013;63(607):e88-96.

Barnes, J. Carmichael, OT. Leung, KK. [et al]; Alzheimer's Disease Neuroimaging Initiative (2013). Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls.Neurobiology of Aging. August 2013;34(8):1996-2002. Full Text Link.

Young-Onset Dementia

Bakker, C. de Vugt, ME. van Vliet, D. [et al](2013). Unmet needs and health-related quality of life in young-onset dementia.The American Journal of Geriatric Psychiatry. July 17th2013.

Kuruppu, DK. Matthews, BR. (2013). Young-onset dementia. Seminars in Neurology. September 2013; 33(4): 365-85.