Critical Care & Anaesthesia- April 2012

 

 

Critical Care & Anaesthesia –Update  

 

 


April 2012

Welcome to the April bulletin of 2012 highlighting new evidence published on selected topics relating to Critical Care, Anaesthesia, Pain and Resuscitation. This bulletin will continue in its current format following a positive evaluation by staff. Full text articles can be accessed via your HEFT Athens ID.

Anaesthesia

The following sub-topics are covered:

  • Cell salvage in surgery (including obstetric surgery)
  • Anaesthesia and surgical outcomes (including epidurals, regional anaesthesia)
  • Anaesthesia and Immunomodulation
  • Anaesthesia and post operative confusion

 

Title: Intraoperative red cell salvage in head and neck surgery

Citation: British Journal of Oral and Maxillofacial Surgery, April 2012, vol./is. 50/3(272-274), 0266-4356;1532-1940 (April 2012) Author(s): Nusrath M.A., Edge C.J., Ahmed-Nusrath A.


 

Title: Blood transfusions in radical prostatectomy: A contemporary population-based analysis

Citation: Urology, February 2012, vol./is. 79/2(332-338), 0090-4295;1527-9995 (February 2012) Author(s): Schmitges J., Sun M., Abdollah F., Trinh Q.-D., Jeldres C., Budus L., Bianchi M., Hansen J., Schlomm T., Perrotte P., Graefen M., Karakiewicz P.I.

Abstract: The aim of this study is to examine the homologous blood transfusion (HBT), autologous blood transfusion (ABT) and intraoperative blood conservation technique (IOBCT) rates and trends at open (ORP) and minimally invasive radical prostatectomy (MIRP).

Full Text: Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

Title: On the role of iron therapy for reducing allogeneic blood transfusion in orthopaedic surgery

Citation: Blood Transfusion, 2012, vol./is. 10/1(8-22), 1723-2007 (2012) Author(s): Munoz M., Garcia-Erce J.A., Cuenca J., Bisbe E., Naveira E.

Full Text: Available in fulltext at National Library of Medicine


 

 

 

 

Title: Coagulopathy associated with massive cell salvage transfusion following aortic surgery

Citation: Perfusion, January 2012, vol./is. 27/1(30-33), 0267-6591;1477-111X (January 2012) Author(s): Rollins K.E., Trim N.L., Luddington R.J., Colah S., Klein A., Besser M.W., Nair S.K.

Abstract: The authors present the case of a 74-year-old female who underwent complicated aortic surgery and was transfused large volumes of cell-saved blood due to post-operative bleeding, which subsequently led to coagulopathy. 2011 The Author(s).

Full Text: Available in fulltext at EBSCOhost Available in fulltext at ProQuest


 

Title: A comparative study of efficacy and outcomes of large loop excision of the transformation zone procedure performed under general anaesthesia versus local anaesthesia

Citation: Australian and New Zealand Journal of Obstetrics and Gynaecology, April 2012, vol./is. 52/2(128-132), 0004-8666;1479-828X (April 2012) Author(s): Borbolla Foster A., Symonds I.

Abstract: This study aims to identify the proportion of women who have a LLETZ under general anaesthesia and to establish the impact of mode of anaesthesia on outcomes including treatment efficacy, overtreatment (negative histology), short-term morbidity and attendance for follow-up.


 

Title: Topical anesthesia versus regional anesthesia for cataract surgery: A meta-analysis of randomized controlled trials

Citation: Ophthalmology, April 2012, vol./is. 119/4(659-667), 0161-6420;1549-4713 (April 2012) Author(s): Zhao L.-Q., Zhu H., Zhao P.-Q., Wu Q.-R., Hu Y.-Q.

Abstract: The purpose of this article is to examine possible differences in the clinical outcomes of topical anesthesia (TA) and regional anesthesia including retrobulbar anesthesia (RBA) and peribulbar anesthesia (PBA) in phacoemulsification.

Full Text: Available in fulltext at Elsevier; Note: You will need to register (free of charge) with Science Direct the first time you use it.


 

Title: Technical aspects of anesthesia and cardiopulmonary bypass in patients undergoing totally thoracoscopic cardiac surgery

Citation: Journal of Cardiothoracic and Vascular Anesthesia, April 2012, vol./is. 26/2(270-273), 1053-0770;1532-8422 (April 2012) Author(s): Zhang Z.-W., Zhang X.-J., Li C.-Y., Ma L.-L., Wang L.-X.

Abstract: The objective of this article is to report on the use of fast-track general anesthesia in patients undergoing nonrobotically assisted and totally thoracoscopic cardiac surgeries.


 

Title: A within-subject comparison of propofol and methohexital anesthesia for electroconvulsive therapy

Citation: Journal of ECT, March 2012, vol./is. 28/1(14-19), 1095-0680;1533-4112 (March 2012) Author(s): Vaidya P.V., Anderson E.L., Bobb A., Pulia K., Jayaram G., Reti I.

Abstract: The optimal anesthetic for electroconvulsive therapy (ECT) is a frequently studied but unresolved issue. Methohexital and propofol are 2 widely used anesthetic agents for ECT. The purpose of this study was to determine which of the 2 agents was associated with superior clinical outcomes.


 

Title: Severe thrombocytopenia in an immune thrombocytopenic parturient non-responder to medical line of treatment: Anaesthetic management for splenectomy combined with caesarean section

Citation: Indian Journal of Hematology and Blood Transfusion, March 2012, vol./is. 28/1(54-57), 0971-4502;0974-0449 (March 2012) Author(s): Karne V., Patil M.

Abstract: The authors report anaesthesia management of a parturient with severe thrombocytopenia secondary to immune thrombocytopenic purpura (ITP).


 

Title: Is there a benefit of awake thoracoscopic surgery in patients with secondary spontaneous pneumothorax?.

Citation: Journal of Thoracic & Cardiovascular Surgery, March 2012, vol./is. 143/3(613-6), 0022-5223;1097-685X (2012 Mar) Author(s): Noda M, Okada Y, Maeda S, Sado T, Sakurada A, Hoshikawa Y, Endo C, Kondo T

Abstract: The purpose of the present study was to retrospectively compare the outcomes of video-assisted thoracic surgery in awake and anesthetized patients in the treatment of secondary spontaneous pneumothorax.

Full Text: Available in fulltext at Ovid


 

Title: Effect of intravenous dexmedetomidine infusion on some proinflammatory cytokines, stress hormones and recovery profile in major abdominal surgery

Citation: Alexandria Journal of Medicine, March 2012, vol./is. 48/1(3-8), 2090-5068 (March 2012) Author(s): Yacout A.G., Osman H.A., Abdel-Daem M.H., Hammouda S.A., Elsawy M.M.

Abstract: This study was designed to evaluate the effect of intravenous dexmedetomidine infusion in patients undergoing major abdominal surgery on stress response markers as plasma interleukin-6, cortisol and blood glucose level. It also assessed its effect on recovery profile and postoperative pain.


 

Cardiac arrests/cardiopulmonary resuscitation (CPR)

The following sub-topics are covered:

  • Quality of CPR
  • Use of feedback devices
  • Leadership and team factors

 

Title: Impact of the European paediatric life support course on knowledge of resuscitation guidelines among Austrian emergency care providers

Citation: Minerva Anestesiologica, April 2012, vol./is. 78/4(434-441), 0375-9393 (April 2012)Author(s): Schebesta K., Rossler B., Kimberger O., Hupfl M.

Abstract: As the knowledge of international guidelines varies widely, highly standardized European Paediatric Life Support (EPLS) courses have been introduced to improve standards of care. This national survey among Austrian anaesthetists and EPLS course participants evaluated the impact of this course at the end of the guideline period 2005-2010.


 

Title: Quantitative waveform measures of the electrocardiogram as continuous physiologic feedback during resuscitation with cardiopulmonary bypass

Citation: Resuscitation, April 2012, vol./is. 83/4(505-510), 0300-9572;1873-1570 (April 2012) Author(s): Salcido D.D., Kim Y.-M., Sherman L.D., Housler G., Teng X., Logue E.S., Menegazzi J.J.

Abstract: This study applied an existing technology - quantitative waveform measures (QWMs) of the ventricular fibrillation (VF) electrocardiogram (ECG) - as a continuous measure of myocardial response to reperfusion with cardiopulmonary bypass (CPB) after prolonged cardiac arrest.

Full Text: Available in fulltext at Elsevier; Note: You will need to register (free of charge) with Science Direct the first time you use it.


 

Title: Human factors in resuscitation teaching

Citation: Resuscitation, April 2012, vol./is. 83/4(423-427), 0300-9572;1873-1570 (April 2012) Author(s): Norris E.M., Lockey A.S.

Abstract: The aim of this paper is to explore how human factors might be taught on resuscitation courses, and improve course outcomes in terms of improved mortality and morbidity for patients. The delivery of human factors training is important and this review explores the work that has been delivered already and areas for future research and teaching.

Full Text: Available in fulltext at Elsevier; Note: You will need to register (free of charge) with Science Direct the first time you use it.


Title: Major changes in the European Resuscitation Council Guidelines for Cardiopulmonary Resuscitation 2010 in the field of Adult Basic and Advanced Life Support

Citation: Vojnosanitetski Pregled, March 2012, vol./is. 69/3(265-269), 0042-8450 (March 2012) Author(s): Jevdjic J., Surbatovic M., Stankovic N., Raffay V., Fiser Z., Jovanovic D.

Full Text: Available in fulltext at EBSCOhost


 

Title: Characterizing cardiopulmonary arrest during interventional radiology procedures

Citation: Journal of Vascular and Interventional Radiology, March 2012, vol./is. 23/3 SUPPL. 1(S102-S103), 1051-0443 (March 2012) Author(s): Rueb G.R., Brady W.J., Gilliland C.A., Patrie J.T., Saad W., Turba U.C., Sabri S.S., Park A., Stone J., Angle J.F.

Abstract: The aim of this study is  to identify risk factors for cardiopulmonary arrest (CPA) during interventional radiology (IR) procedures.


 

Title: Comparative quality analysis of hands-off time in simulated basic and advanced life support following European Resuscitation Council 2000 and 2005 guidelines.

Citation: Emergency Medicine Journal, February 2012, vol./is. 29/2(95-9), 1472-0205;1472-0213 (2012 Feb) Author(s): Ilper H, Kunz T, Pfleger H, Schalk R, Byhahn C, Ackermann H, Breitkreutz R

Abstract: The aim of this article is to compare hands-off time (HOT) in simulated advanced life support (ALS) following European Resuscitation Council (ERC) 2005 guidelines and ERC 2000 and to provide quantitative data on workflow.

Full Text: Available in fulltext at Highwire Press

Critical Care

The following sub-topics are covered:

  • Sepsis – the use of statins, biomarker MMP9
  • Acute lung injury (ALI)/adult respiratory distress syndrome (ARDS)
  • Use of non invasive ventilation (NIV) in weaning
  • Ventilator associate pneumonia (including E.Coli)

 

Title: Statins for sepsis: Has their time come?

Citation: Critical Care Medicine, April 2012, vol./is. 40/4(1336-1337), 0090-3493;1530-0293 (April 2012) Author(s): Artero A.

Full Text: Available in fulltext at Ovid


 

Title: Matrix metalloproteinase-8 as a potential drug target for the therapy of sepsis

Citation: Critical Care Medicine, February 2012, vol./is. 40/2(655-656), 0090-3493;1530-0293 (February 2012) Author(s): Fink M.P.

Full Text: Available in fulltext at Ovid


 

Title: Acute lung injury in critical neurological illness

Citation: Critical Care Medicine, February 2012, vol./is. 40/2(587-593), 0090-3493;1530-0293 (February 2012) Author(s): Hoesch R.E., Lin E., Young M., Gottesman R.F., Altaweel L., Nyquist P.A., Stevens R.D.

Abstract: Objective: Acute lung injury and acute respiratory distress syndrome have been reported in a significant proportion of patients with critical neurologic illness. The aim of the study was to identify risk factors for acute lung injury/acute respiratory distress syndrome in this population.

Full Text: Available in fulltext at Ovid


 

Title: Early use of noninvasive positive pressure ventilation for acute lung injury: A multicenter randomized controlled trial

Citation: Critical Care Medicine, February 2012, vol./is. 40/2(455-460), 0090-3493;1530-0293 (February 2012) Author(s): Zhan Q., et al

Abstract: Aim of this study was to assess the safety and efficacy of noninvasive positive pressure ventilation for patients with acute lung injury and compare this with high-concentration oxygen therapy.

Full Text: Available in fulltext at Ovid


 

Title: Depressive symptoms and impaired physical function after acute lung injury: A 2-year longitudinal study

Citation: American Journal of Respiratory and Critical Care Medicine, March 2012, vol./is. 185/5(517-524), 1073-449X;1535-4970 (01 Mar 2012) Author(s): Bienvenu O.J., Colantuoni E., Mendez-Tellez P.A., Dinglas V.D., Shanholtz C., Husain N., Dennison C.R., Herridge M.S., Pronovost P.J., Needham D.M.

Abstract: The objective of the study was to evaluate the 2-year incidence and duration of depressive symptoms and physical impairment after ALI, as well as risk factors for these conditions.

Full Text: Available in fulltext at ProQuest


 

Title: Embracing physical and neuropsychological dysfunction in acute lung injury survivors: The time has come

Citation: American Journal of Respiratory and Critical Care Medicine, March 2012, vol./is. 185/5(470-471), 1073-449X;1535-4970 (01 Mar 2012) Author(s): Azoulay E., Moss M.

Full Text: Available in fulltext at ProQuest


 

Title: Measuring metabolomics in acute lung injury: Choosing the correct compartment?

Citation: American Journal of Respiratory and Critical Care Medicine, April 2012, vol./is. 185/7(789), 1073-449X;1535-4970 (01 Apr 2012) Author(s): Bos L.D.J., Sterk P.J., Schultz M.J.

Full Text: Available in fulltext at ProQuest


Title: Hypercapnia: A nonpermissive environment for the lung

Citation: American Journal of Respiratory Cell and Molecular Biology, April 2012, vol./is. 46/4(417-421), 1044-1549 (April 2012) Author(s): Vadasz I., Hubmayr R.D., Nin N., Sporn P.H.S., Sznajder J.I.

Abstract: This article reviews recent research on how elevated CO<sub>2</sub> is sensed by cells in the lung and the potential harmful effects of hypercapnia on epithelial and endothelial barrier, lung edema clearance, innate immunity, and host defense. In view of these findings, the authors raise concerns about the potentially deleterious effects hypercapnia may have in patients with acute and chronic lung diseases.

Full Text: Available in fulltext at ProQuest


 

Title: The role of ventilation-induced surfactant dysfunction and atelectasis in causing acute respiratory distress syndrome

Citation: American Journal of Respiratory and Critical Care Medicine, April 2012, vol./is. 185/7(702-708), 1073-449X;1535-4970 (01 Apr 2012) Author(s): Albert R.K.

Abstract: This Pulmonary Perspective describes a new pathophysiologic scenario by which the acute respiratory distress syndrome (ARDS) might develop, summarizes the literature on which this new scenario is based, and discusses the resulting implications with respect to patient management.

Full Text: Available in fulltext at ProQuest


 

Title: Risk factors for the development of acute lung injury in patients with infectious pneumonia

Citation: Critical Care, March 2012, vol./is. 16/2, 1364-8535;1466-609X (14 Mar 2012) Author(s): Kojicic M., Li G., Hanson A.C., Lee K.-M., Thakur L., Vedre J., Ahmed A., Baddour L.M., Ryu J.H., Gajic O.

Abstract: The objective of this study was to determine frequency, risk factors, and outcome of ALI in patients with infectious pneumonia.

Full Text: Available in selected fulltext at BioMedCentral


 

 

 

 

Title: Negative- versus positive-pressure ventilation in intubated patients with acute respiratory distress syndrome

Citation: Critical Care, March 2012, vol./is. 16/2, 1364-8535;1466-609X (02 Mar 2012) Author(s): Raymondos K., Molitoris U., Capewell M., Sander B., Dieck T., Ahrens J., Weilbach C., Knitsch W., Corrado A.

Abstract:: Recent experimental data suggest that continuous external negative-pressure ventilation (CENPV) results in better oxygenation and less lung injury than continuous positive-pressure ventilation (CPPV). The effects of CENPV on patients with acute respiratory distress syndrome (ARDS) remain unknown.

Full Text: Available in selected fulltext at BioMedCentral


 

Title: Quantifying the severity of acute lung injury using dead-space ventilation: should the lung injury score be updated?.

Citation: Respiratory Care, March 2012, vol./is. 57/3(477-9), 0020-1324;0020-1324 (2012 Mar) Author(s): Kallet RH, Alonso JA, Matthay MA


 

Title: Potential effects of corticosteroids on physiological dead-space fraction in acute respiratory distress syndrome.

Citation: Respiratory Care, March 2012, vol./is. 57/3(377-83), 0020-1324;0020-1324 (2012 Mar) Author(s): Raurich JM, Ferreruela M, Llompart-Pou JA, Vilar M, Colomar A, Ayestaran I, Perez-Barcena J, Ibanez J

Abstract: The study evaluated the changes in the oxygenation and dead-space fraction in patients with persistent ARDS after corticosteroid therapy.


 

Title: Ventilator-associated pneumonia caused by ESKAPE organisms: Cause, clinical features, and management

Citation: Current Opinion in Pulmonary Medicine, May 2012, vol./is. 18/3(187-193+280-281), 1070-5287;1531-6971 (May 2012) Author(s): Sandiumenge A., Rello J.

Abstract: This review updates information on VAP due to ESKAPE pathogens.


 

Title: Burns, inhalation injury and ventilator-associated pneumonia: Value of routine surveillance cultures

Citation: Burns, May 2012, vol./is. 38/3(364-370), 0305-4179;1879-1409 (May 2012)

Author(s): Brusselaers N., Logie D., Vogelaers D., Monstrey S., Blot S.

Abstract: The objective was to assess the incidence of VAP in burn patients with inhalation injury, and the benefit of routine surveillance cultures to predict multidrug resistant (MDR) pathogens.


 

Title: Is a ventilator-associated pneumonia rate of zero really possible?

Citation: Current Opinion in Infectious Diseases, April 2012, vol./is. 25/2(176-182), 0951-7375;1473-6527 (April 2012) Author(s): Klompas M.

Abstract: This article explores the significance of very low VAP rates, reviews differences in surveillance and clinical rates, proposes reasons for their discrepancies, and suggests possible objective alternatives for surveillance.


 

Title: Overview of adverse events related to invasive procedures in the intensive care unit

Citation: American Journal of Infection Control, April 2012, vol./is. 40/3(241-246), 0196-6553;1527-3296 (April 2012) Author(s): Pottier V., Daubin C., Lerolle N., Gaillard C., Viquesnel G., Plaud B., Hanouz J.-L., Charbonneau P.

Abstract: This study was conducted to determine the frequency, predictors, and clinical impact of adverse events (AEs) related to invasive procedures in the intensive care unit (ICU).

Full Text: Available in print at Heartlands Staff Library


 

Title: A cost-effectiveness analysis of reducing ventilator-associated pneumonia at a Danish ICU with ventilator bundle

Citation: Journal of Medical Economics, April 2012, vol./is. 15/2(285-292), 1369-6998;1941-837X (April 2012) Author(s): Moller A.H., Hansen L., Jensen M.S., Ehlers L.H.

Abstract: The aim was to determine cost-effectiveness of implementing the Ventilator bundle (VB), thereby reducing ventilator-associated pneumonia (VAP), when treating a ventilated patient, compared to standard procedure.


 

Title: Ventilator-associated pneumonia: The potential critical role of emergency medicine in prevention

Citation: Journal of Emergency Medicine, March 2012, vol./is. 42/3(353-362), 0736-4679 (March 2012) Author(s): Grap M.J., Munro C.L., Unoki T., Hamilton V.A., Ward K.R.

Abstract: This article summarizes the epidemiology, pathophysiology, and specific risk factors associated with VAP and provides evidence-based recommendations for its prevention.


 

Title: What is the efficacy and safety of colistin for the treatment of ventilator-associated pneumonia? A systematic review and meta-regression

Citation: Clinical Infectious Diseases, March 2012, vol./is. 54/5(670-680), 1058-4838;1537-6591 (01 Mar 2012) Author(s): Florescu D.F., Qiu F., McCartan M.A., Mindru C., Fey P.D., Kalil A.C.

Abstract: The study aimed to assess the safety and efficacy of colistin for the treatment of VAP.


 

Title: Economic impact of ventilator-associated pneumonia in a large matched cohort

Citation: Infection Control and Hospital Epidemiology, March 2012, vol./is. 33/3(250-256), 0899-823X (March 2012) Author(s): Kollef M.H., Hamilton C.W., Ernst F.R.

Abstract: Aim is to evaluate the economic impact of ventilator-associated pneumonia (VAP) on length of stay and hospital costs.


 

 

 

 

 

Title: Evolution of surfactant protein-D levels in children with ventilator-associated pneumonia

Citation: Pediatric Pulmonology, March 2012, vol./is. 47/3(292-299), 8755-6863;1099-0496 (March 2012) Author(s): Said A.S., Abd-Elaziz M.M., Farid M.M., Abd-Elfattah M.A., Abdel-Monim M.T., Doctor A.

 

Abstract: The authors evaluated the clinical pulmonary infection score (CPIS) in diagnosing VAP and prospectively characterized the relationship between surfactant protein-D (SP-D) metabolism and VAP.


 

 

 

 

 

 

 

 

 

 

Further Information:

The following sources have been scanned for evidence published in the previous 8 weeks: Lancet, BMJ, JAMA, NEJM and American Journal of Critical Care Medicine; and articles from other journals as retrieved via searches on MEDLINE and EMBASE are also listed.

For a detailed list of sources that have been scanned, please contact [email protected]

To access the full text links in this bulletin, login with your HEFT Athens ID at

http://www.evidence.nhs.uk/nhs-evidence-content/journals-and-databases ‘before’ clicking on them in order to make them seamless

 

For more information on how to register for Athens, access the Athens Registration leaflet via HEFT Library website www.heftlibrary.nhs.uk

Visit NHS Evidence portal www.evidence.nhs.uk  to access your journals and healthcare databases.