Critical Care & Anaesthesia- November 2011

 

 

Critical Care & Anaesthesia – Evidence Update  

November- 2011

 

 

 


Welcome to the November bulletin highlighting new evidence published on selected topics relating to Critical Care, Anaesthesia, Pain and Resuscitation. Journals such as – Lancet, BMJ, JAMA, NEJM and American Journal of Critical Care Medicine have been scanned to identify relevant articles. Articles from other journals as retrieved via searches on MEDLINE and EMBASE are also listed. This bulletin features evidence published in the previous 8 weeks. Full text articles can be accessed via your HEFT Athens ID.

Anaesthesia

The following sub-topics are covered:

  • Cell salvage in surgery (including obstetric surgery)
  • Anaesthesia and surgical outcomes (including epidurals, regional anaesthesia)
  • Anaesthesia and Immunomodulation
  • Anaesthesia and post operative confusion

 

Title: Intraoperative cell salvaged blood as part of a blood conservation strategy in Caesarean section: is fetal red cell contamination important?.

Citation: British Journal of Anaesthesia, September 2011, vol./is. 107/3(404-8), 0007-0912;1471-6771 (2011 Sep) Author(s): Ralph CJ, Sullivan I, Faulds J

Abstract: In this study, the authors attempted to quantify the risk of antibody formation from re-infusion of autologous blood after Caesarean section.

Full Text: Available in fulltext at EBSCO Host EJS Available in print at Solihull Staff Library


 

Title: Intraoperative cell salvage in obstetrics: Is it a real therapeutic option?

Citation: Transfusion, October 2011, vol./is. 51/10(2244-2256), 0041-1132;1537-2995 (October 2011)Author(s): Liumbruno G.M., Liumbruno C., Rafanelli D.

Abstract: The authors highlight that the role of cell salvage as a blood-saving measure in obstetrics is progressively acquiring relevance and conclude that , intraoperative cell salvage in obstetrics should be considered in patients at high risk for hemorrhage or in cases where allogeneic blood transfusion is difficult or impossible.

 


 

Title: The volume of returned red blood cells in a large blood salvage program: Where does it all go?

Citation: Transfusion, October 2011, vol./is. 51/10(2126-2132), 0041-1132;1537-2995 (October 2011) Author(s): Waters J.H., Dyga R.M., Waters J.F.R., Yazer M.H.

Abstract: The study analyzed the trends in the volume of returned RBCs by a blood salvage program across a 12-hospital regional health care system over a 5-year period.


 

Title: Blood cell salvage during cesarean delivery

Citation: International Journal of Gynecology and Obstetrics, November 2011, vol./is. 115/2(161-163), 0020-7292;1879-3479 (November 2011) Author(s): Sullivan J.V., Crouch M.E., Stocken G., Lindow S.W.

Abstract: The study reviews the use of blood cell salvage performed during caesarean delivery.

 


 

Title: A quality assurance programme for cell salvage in cardiac surgery

Citation: Anaesthesia, October 2011, vol./is. 66/10(901-906), 0003-2409;1365-2044 (October 2011) Author(s): Kelleher A., Davidson S., Gohil M., MacHin M., Kimberley P., Hall J., Banya W.

Abstract: At the same time as cell salvage was introduced into our institution for all patients undergoing cardiac surgery with cardiopulmonary bypass, the authors established a supporting programme of quality assurance to reassure clinicians regarding safety and efficacy.


 

Title: Intraoperative blood loss and component utilization in hand and upper extremity allotransplantation

Citation: Transfusion, September 2011, vol./is. 51/(184A), 0041-1132 (September 2011)Author(s): Raval J.S., Lang R.S., Lee W., Planinsic R.M., Kiss J.E.

Abstract: The study sought to characterize the IO blood losses and hematological data of patients during HUT to better predict the blood utilization needs of transplant teams at our medical center.


 

Title: Continuous cell saver circuits for non-cardiac surgery patients who refuse allogeneic transfusion

Citation: Transfusion, September 2011, vol./is. 51/(184A), 0041-1132 (September 2011) Author(s): Inman A., Wheeler K., Figueroa P.I., Bakdash S.

Abstract:  The authors aim to provide a detailed information on continuous cell saver circuit utilization with respect to Jehovah’s witness patients.

 


 

Title: Development and validation of a generalizable model for predicting major transfusion during spine fusion surgery

Citation: Journal of Neurosurgical Anesthesiology, October 2011, vol./is. 23/4(416), 0898-4921 (October 2011)Author(s): Carabini L.M., Moreland N., Zeeni C., Gould R.W., Gupta D.K.

Abstract: The aim of this study was to identify and validate independent predictors of the need for major transfusion in any spine fusion surgery of Z3 levels to assist with preoperative risk stratification.


 

Title: Immune cell populations decrease during craniotomy under general anesthesia.

Citation: Anesthesia & Analgesia, September 2011, vol./is. 113/3(572-7), 0003-2999;1526-7598 (2011 Sep) Author(s): Liu S, Wang B, Li S, Zhou Y, An L, Wang Y, Lv H, Zhang G, Fang F, Liu Z, Han R, Jiang T, Kang X

Abstract: The aim of the study was to investigate how the immune cell population changes during the anesthesia process in patients undergoing craniotomy surgery.

Full Text: Available in fulltext at Ovid


 

Title: Extending epidural analgesia for emergency Caesarean section: A meta-analysis

Citation: British Journal of Anaesthesia, November 2011, vol./is. 107/5(668-678), 0007-0912;1471-6771 (November 2011) Author(s): Hillyard S.G., Bate T.E., Corcoran T.B., Paech M.J., O'Sullivan G.

Abstract: The aim of this meta-analysis was to identify the best epidural solutions for emergency Caesarean section anaesthesia, with respect to rapid onset and low supplementation of intraoperative block. Full Text: Available in fulltext at EBSCO Host EJS

Available in print at Solihull Staff Library


 

Title: Prospective randomized observer-blinded study comparing the analgesic efficacy of ultrasound-guided rectus sheath block and local anaesthetic infiltration for umbilical hernia repair

Citation: British Journal of Anaesthesia, November 2011, vol./is. 107/5(790-795), 0007-0912;1471-6771 (November 2011) Author(s): Gurnaney H.G., Maxwell L.G., Kraemer F.W., Goebel T., Nance M.L., Ganesh A.

Abstract: The authors of this study undertook an observer-blinded, randomized, prospective, observational study to compare the efficacy of ultrasound-guided RSB and LAI in providing postoperative analgesia for umbilical hernia repair.

Full Text: Available in fulltext at EBSCO Host EJS Available in print at Solihull Staff Library


 

Title: General anaesthesia is associated with increased risk of surgical site infection after Caesarean delivery compared with neuraxial anaesthesia: A population-based study

Citation: British Journal of Anaesthesia, November 2011, vol./is. 107/5(757-761), 0007-0912;1471-6771 (November 2011) Author(s): Tsai P.-S., Hsu C.-S., Fan Y.-C., Huang C.-J.

Abstract: This study compared the odds ratio (OR) of surgical site infection (SSI) within 30 days after operation with general anaesthesia (GA) or neuraxial anaesthesia (NA) in Taiwanese women undergoing Caesarean delivery (CD).

Full Text: Available in fulltext at EBSCO Host EJS Available in print at Solihull Staff Library


 

Title: Combined spinal and epidural anaesthesia and maternal intrapartum temperature during vaginal delivery: A randomized clinical trial

Citation: British Journal of Anaesthesia, November 2011, vol./is. 107/5(762-768), 0007-0912;1471-6771 (November 2011) Author(s): De Orange F.A., Passini Jr. R., Amorim M.M.R., Almeida T., Barros A.

Abstract: The study determined the association between combined spinalepidural (CSE) anaesthesia and an increase in maternal intrapartum temperature and intrapartum fever. Full Text: Available in fulltext at EBSCO Host EJS Available in print at Solihull Staff Library


Title: Spinal anaesthesia and monitored conscious sedation for repair of infantile meningomyelocele

Citation: Child's Nervous System, November 2011, vol./is. 27/11(1985-1988), 0256-7040;1433-0350 (November 2011) Author(s): Idowu O.E., Oyeleke S.O.

Abstract: Objectives: The study monitored conscious sedation combined with spinal anaesthesia.


 

Title: General or local anesthesia for carotid endarterectomy-The "real-World" experience

Citation: Angiology, November 2011, vol./is. 62/8(609-613), 0003-3197;1940-1574 (November 2011) Author(s): Sideso E., Walton J., Handa A.

Abstract: The aim of this study was to assess the complication rates in patients undergoing CEA under general anesthesia (GA) or regional anesthesia (local anesthesia [LA]).

Full Text: Available in fulltext at EBSCO Host


 

Title: Ultrasound-guided suprascapular nerve block for shoulder reduction and adhesive capsulitis in the ED

Citation: American Journal of Emergency Medicine, October 2011, vol./is. 29/8(963.e1-963.e3), 0735-6757;1532-8171 (October 2011) Author(s): Herring A.A., Stone M.B., Nagdev A.

Full Text: Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

Title: The nerve stimulation technique versus the loss of resistance technique for the posterior approach to lumbar plexus block: A randomized, prospective, observer-blinded, pilot study

Citation: Minerva Anestesiologica, October 2011, vol./is. 77/10(959-963), 0375-9393 (October 2011) Author(s): Danelli G., Ghisi D., Bellinghieri F., Borghi B., Fanelli G., Chelly J.E.

Abstract: This prospective, randomized, observer-blinded, pilot study compares the effects of the nerve stimulation guidance technique (NS) with the loss of resistance technique (LOR) on readiness for surgery during the posterior approach to lumbar plexus block.


 

Title: Maternal cardiac output changes after crystalloid or colloid coload following spinal anesthesia for elective cesarean delivery: A randomized controlled trial

Citation: Anesthesia and Analgesia, October 2011, vol./is. 113/4(803-810), 0003-2999 (October 2011) Author(s): McDonald S., Fernando R., Ashpole K., Columb M.

Abstract: The study hypothesized that a colloid coload compared with a crystalloid coload would produce a larger sustained increase in CO and therefore reduce vasopressor requirements. Full Text: Available in fulltext at Ovid


 

 

 

 

Title: Does the baricity of bupivacaine influence intrathecal spread in the prolonged sitting position before elective cesarean delivery? A prospective randomized controlled study

Citation: Anesthesia and Analgesia, October 2011, vol./is. 113/4(811-817), 0003-2999 (October 2011) Author(s): Loubert C., Hallworth S., Fernando R., Columb M., Patel N., Sarang K., Sodhi V.

Abstract: The authors hypothesized that the delay between the spinal injection of the local anesthetic mixture and the adoption of the supine position with lateral tilt, may affect the intrathecal distribution of local anesthetic of different baricities such that hypobaric local anesthetic would lead to a higher sensory block level.

Full Text: Available in fulltext at Ovid


 

Title: A randomized study of the effectiveness of suprascapular nerve block in patient satisfaction and outcome after arthroscopic subacromial decompression

Citation: Arthroscopy - Journal of Arthroscopic and Related Surgery, October 2011, vol./is. 27/10(1323-1328), 0749-8063;1526-3231 (October 2011) Author(s): Jeske H.-C., Kralinger F., Wambacher M., Perwanger F., Schoepf R., Oberladstaetter J., Krappinger D., Dallapozza C., Hoffmann F.

Abstract: The purpose of this study was to evaluate the efficiency of the suprascapular nerve (SSN) block in pain reduction after arthroscopic subacromial decompression operations and its influence on patient satisfaction.


 

Title: The minimum effective anesthetic volume of 0.75% ropivacaine in ultrasound-guided interscalene brachial plexus block

Citation: Anesthesia and Analgesia, October 2011, vol./is. 113/4(951-955), 0003-2999 (October 2011) Author(s): Gautier P., Vandepitte C., Ramquet C., Decoopman M., Xu D., Hadzic A.

Abstract: In the current study, the authors investigated the minimal volume necessary to accomplish surgical anesthesia with interscalene brachial plexus block.

Full Text: Available in fulltext at Ovid


 

Title: Comparison of intratracheal and intravenous lidocaine effects on bucking, cough, and emergence time at the end of anesthesia

Citation: Pakistan Journal of Medical Sciences, October 2011, vol./is. 27/4(793-796), 1682-024X (October 2011) Author(s): Khezri M.-B., Jalili S., Asefzadeh S., Kayalha A.

Abstract: The aim of the study was to compare the effects of intratracheal and intravenous lidocaine on bucking, cough and emergence time at the end of anesthesia.


 

Title: Awake coronary artery bypass grafting under thoracic epidural anesthesia: Great impact on off-pump coronary revascularization and fast-track recovery

Citation: European Journal of Cardio-thoracic Surgery, October 2011, vol./is. 40/4(788-793), 1010-7940;1873-734X (October 2011) Author(s): Watanabe G., Tomita S., Yamaguchi S., Yashiki N.

Abstract: The ultimate goal of minimally invasive coronary artery bypass grafting (CABG) is day surgery. This study evaluated the potential of a new awake CABG protocol using only epidural anesthesia in realizing day surgery.


Title: Local anaesthesia for endovascular repair of infrarenal aortic aneurysms

Citation: European Journal of Vascular and Endovascular Surgery, October 2011, vol./is. 42/4(467-473), 1078-5884;1532-2165 (October 2011) Author(s): Geisbusch P., Katzen B.T., MacHado R., Benenati J.F., Pena C., Tsoukas A.I.

Abstract: The study aimed to analyse and report the results of a 'local anaesthesia first' approach in elective endovascular aneurysm repair (EVAR) patients.


 

Title: Transilluminated powered phlebectomy in an office setting: Procedural considerations and clinical outcomes

Citation: Journal of Endovascular Therapy, October 2011, vol./is. 18/5(734-738), 1526-6028;1545-1550 (October 2011) Author(s): Spitz G.

Abstract: To report a series of non-sedated patients treated with transilluminated powered phlebectomy (TIPP) under tumescent anesthesia in an office setting.


 

Title: Intraoperative epidural analgesia prevents the early proinflammatory response to surgical trauma. Results from a prospective randomized clinical trial of intraoperative epidural versus general analgesia

Citation: Annals of Surgical Oncology, October 2011, vol./is. 18/10(2722-2731), 1068-9265;1534-4681 (October 2011) Author(s): Moselli N.M., Baricocchi E., Ribero D., Sottile A., Suita L., Debernardi F.

Abstract: This study investigates the effect of intraoperative EA versus intravenous analgesia (IA) on the immune function.


 

Title: Time-dependent perioperative anesthetic management and outcomes of the first 100 consecutive cases of spring-assisted surgery for sagittal craniosynostosis

Citation: Paediatric Anaesthesia, October 2011, vol./is. 21/10(1015-1019), 1155-5645;1460-9592 (October 2011) Author(s): Ririe D.G., Smith T.E., Wood B.C., Glazier S.S., Couture D.E., Argenta L.C., David L.R.

Abstract: Background: The anesthetic risks and outcomes of the first 100 consecutive spring-assisted surgeries (SAS) for cranial expansion from a single institution are reported. The effect of number of procedures was also tested on hematocrit postoperative day 1 (POD1), anesthesia time, and surgery time of the first procedure.

Full Text: Available in fulltext at EBSCO Host


 

Title: Right thoracic paravertebral anaesthesia for percutaneous radiofrequency ablation of liver tumours

Citation: British Journal of Radiology, September 2011, vol./is. 84/1005(785-789), 0007-1285 (September 2011) Author(s): Cheung Ning M., Karmakar M.K.

Abstract: This prospective study evaluated the efficacy of a right thoracic paravertebral block (TPVB) for anaesthesia and analgesia during PRFA of liver tumours.


 

Title: Obstetric outcomes and maternal satisfaction in nulliparous women using patient-controlled epidural analgesia

Citation: American Journal of Obstetrics and Gynecology, September 2011, vol./is. 205/3(271.e1-271.e6), 0002-9378;1097-6868 (September 2011) Author(s): Haydon M.L., Larson D., Reed E., Shrivastava V.K., Preslicka C.W., Nageotte M.P.

Abstract: The purpose of this study was to compare obstetric outcomes and maternal satisfaction in nulliparous women in spontaneous labor who used patient-controlled epidural analgesia (PCEA) vs continuous epidural infusion (CEI).

Full Text: Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

Title: Management of acquired cardiac disease in the obstetric patient

Citation: Seminars in Cardiothoracic and Vascular Anesthesia, September 2011, vol./is. 15/3(85-97), 1089-2532;1940-5596 (September 2011) Author(s): Wolff G.A., Weitzel N.S.

Abstract: This review systematically presents the pathophysiology, peripartum risk, and anesthetic management in the puerperium of specific acquired cardiac abnormalities including: valvular disease, pulmonary hypertension, cardiomyopathy, cardiac transplantation, ischemia, arrhythmias, and cardiac arrest. 2011 SAGE Publications.

Full Text: Available in fulltext at EBSCO Host


 

Title: Anesthetic considerations for nontransplant procedures in lung transplant patients

Citation: Journal of Clinical Anesthesia, September 2011, vol./is. 23/6(508-516), 0952-8180;1873-4529 (September 2011) Author(s): Feltracco P., Falasco G., Barbieri S., Milevoj M., Serra E., Ori C.

Abstract: Anesthesia and surgery following lung transplantation may be required for various diseases that may affect both systemic organs and the transplanted graft. When a patient with a lung transplant undergoes surgery, there is the potential for interference with lung function, depending on the type of intervention and its anatomical site. Accurate preoperative evaluation, an understanding of the physiology of the transplanted lung, proper airway instrumentation, individualized management of intraoperative ventilation, and fluid balance are essential for a positive perioperative outcome. 2011 Elsevier Inc.

Full Text: Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

Title: Clinical application of the cardioprotective effects of volatile anaesthetics: CON - Total intravenous anaesthesia or not total intravenous anaesthesia to anaesthetise a cardiac patient?

Citation: European Journal of Anaesthesiology, September 2011, vol./is. 28/9(623-627), 0265-0215;1365-2346 (September 2011) Author(s): Van Rompaey N., Barvais L.


 

Title: Effect of carotid sinus nerve blockade on hemodynamic stability during carotid endarterectomy under local anesthesia.

Citation: Journal of Vascular Surgery, August 2011, vol./is. 54/2(386-93), 0741-5214;1097-6809 (2011 Aug) Author(s): Ajduk M, Tudoric I, Sarlija M, Pavic P, Oremus Z, Held R, Patrlj L

Abstract: To find out whether routine carotid sinus nerve blockade with lidocaine during carotid endarterectomy under local anesthesia results in perioperative changes in blood pressure and heart rate.Full Text: Available in fulltext at Ovid


 

 

Cardiac arrests/cardiopulmonary resuscitation (CPR)

The following sub-topics are covered:

  • Quality of CPR
  • Use of feedback devices
  • Leadership and team factors

 

Title: Impact of team leader background and leadership skills on performance in simulated cardiac arrest management

Citation: Anaesthesia, October 2011, vol./is. 66/10(959), 0003-2409 (October 2011)

Author(s): Yeung J., Davies R.P., Field R., Akhtar N., Gao F., Perkins G.D.

Abstract: This study aims to identify the relationship between leadership skills and characteristics and quality of CPR.


Title: Survival from in-hospital cardiac arrest in Auckland City Hospital

Citation: EMA - Emergency Medicine Australasia, October 2011, vol./is. 23/5(569-579), 1742-6731;1742-6723 (October 2011) Author(s): Jones P., Miles J., Mitchell N.

Abstract: The objective of this article is to describe in-hospital resuscitation outcomes and factors associated with survival at Auckland City Hospital, New Zealand.


Title: The consequences of noncompliance with guidelines for withholding or terminating resuscitation in traumatic cardiac arrest patients

Citation: Journal of Trauma - Injury, Infection and Critical Care, October 2011, vol./is. 71/4(997-1002), 0022-5282;1529-8809 (October 2011) Author(s): Mollberg N.M., Wise S.R., Berman K., Chowdhry S., Holevar M., Sullivan R., Vafa A.

Abstract: The purpose of this study is to demonstrate the consequences of violating the current published guidelines and whether EMS personnel were able to accurately identify patients in TCPA.


Title: Perceived stress and team performance during a simulated resuscitation

Citation: Intensive Care Medicine, September 2011, vol./is. 37/9(1473-1479), 0342-4642;1432-1238 (September 2011) Author(s): Hunziker S., Laschinger L., Portmann-Schwarz S., Semmer N.K., Tschan F., Marsch S.

Abstract: The aim of this study was to investigate whether mental stress and different perceived emotions have a negative impact on the performance of rescuers.


 

Critical Care

The following sub-topics are covered:

  • Sepsis – the use of statins, biomarker MMP9
  • Acute lung injury (ALI)/adult respiratory distress syndrome (ARDS)
  • Use of non invasive ventilation (NIV) in weaning
  • Ventilator associate pneumonia (including E.Coli)

 

Title: Noninvasive ventilation and weaning in patients with chronic hypercapnic respiratory failure: A randomized multicenter trial

Citation: American Journal of Respiratory and Critical Care Medicine, September 2011, vol./is. 184/6(672-679), 1073-449X;1535-4970 (15 Sep 2011) Author(s): Girault C., Bubenheim M., Abroug F., Diehl J.L., Elatrous S., Beuret P., Richecoeur J., L'Her E., Hilbert G., Capellier G., Rabbat A., Besbes M., Guerin C., Guiot P., Benichou J., Bonmarchand G.

Abstract: To investigate NIV effectiveness as an early weaning/extubation technique in difficult-to-wean patients with chronic hypercapnic respiratory failure (CHRF). Full Text: Available in fulltext at ProQuest (Legacy Platform)


 

Pro: [Beta]-Agonists in Acute Lung Injury-the End of the Story?
Authors: Gavin D Perkins, Daniel F McAuley. Citation: American Journal of Respiratory and Critical Care Medicine. New York: Sep 1, 2011. Vol. 184, Iss. 5; p. 503 (2 pages) › Full Text: Available in fulltext at Proquest (Legacy Platform)


Title: Serum MMP-8, -9 and TIMP-1 in sepsis: High serum levels of MMP-8 and TIMP-1 are associated with fatal outcome in a multicentre, prospective cohort study. Hypothetical impact of tetracyclines

Citation: Pharmacological Research, December 2011, vol./is. 64/6(590-594), 1043-6618;1096-1186 (December 2011) Author(s): Lauhio A., Hastbacka J., Pettila V., Tervahartiala T., Karlsson S., Varpula T., Varpula M., Ruokonen E., Sorsa T., Kolho E.

Abstract: The authors of this article studied serum levels of MMP-8, MMP-9 and TIMP-1 (tissue inhibitor of matrix metalloproteinase-1) in a multicentre, prospective cohort study of patients with sepsis treated in Intensive Care Units (ICUs). They analyzed serum samples taken on ICU admission from 248 critically ill sepsis patients.


 

Title: Ventilator-associated pneumonia in children after cardiac surgery in The Netherlands

Citation: Intensive Care Medicine, October 2011, vol./is. 37/10(1656-1663), 0342-4642;1432-1238 (October 2011) Author(s): Roeleveld P.P., Guijt D., Kuijper E.J., Hazekamp M.G., De Wilde R.B.P., De Jonge E.

Abstract: The authors conducted a retrospective cohort study in an academic tertiary care center to characterize ventilator-associated pneumonia (VAP) in pediatric patients after cardiac surgery in The Netherlands.


 

Title: Can intravenous colistin effectively treat ventilator-associated pneumonia in the pediatric and neonatal patients?

Citation: European Journal of Pediatrics, October 2011, vol./is. 170/10(1355-1356), 0340-6199;1432-1076 (October 2011) Author(s): Nakwan N., Chokephaibulkit K.


 

Title: Interpreting positive cultures of endotracheal aspirates: Factors associated with treatment decisions in ventilated neonates

Citation: Journal of Paediatrics and Child Health, October 2011, vol./is. 47/10(728-733), 1034-4810;1440-1754 (October 2011) Author(s): Murila F., Francis J.V., Bland A., Kumbla S., Doherty R., Sehgal A.

Abstract: The aims of this study were to review treatment decisions in neonates with culture-positive endotracheal aspirate and to assess impact on respiratory outcomes using blinded review of radiological studies.


Title: Pancreatic stone protein: A marker of organ failure and outcome in ventilator-associated pneumonia

Citation: Chest, October 2011, vol./is. 140/4(925-932), 0012-3692;1931-3543 (October 2011) Author(s): Boeck L., Graf R., Eggimann P., Pargger H., Raptis D.A., Smyrnios N., Thakkar N., Siegemund M., Rakic J., Tamm M., Stolz D.

Abstract: The aim of this pilot study was to evaluate PSP/reg in VAP.

Full Text: Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

Title: Reduction in ventilator associated pneumonia in a mixed intensive care unit after initiation of a novel hand hygiene program

Citation: Journal of Critical Care, October 2011, vol./is. 26/5(489-495), 0883-9441;1557-8615 (October 2011) Author(s): Koff M.D., Corwin H.L., Beach M.L., Surgenor S.D., Loftus R.W.

Abstract: A before and after study design was used to evaluate the impact on the incidence of CRBSI and VAP of a multi-modal program incorporating education, performance feedback, and a body worn hand hygiene device.


 

Title: Serum beta-d-glucan of critically ill patients with suspected ventilator-associated pneumonia: Preliminary observations

Citation: Journal of Critical Care, October 2011, vol./is. 26/5(536.e1-536.e9), 0883-9441;1557-8615 (October 2011) Author(s): Heyland D., Jiang X., Day A.G., Laverdiere M.

Abstract: The purpose of this pilot study was to determine whether beta-d-glucan (BG) was associated with Candida in the lung and risk of death in patients with suspected ventilator-associated pneumonia (VAP).


 

Title: Ventilator-associated pneumonia in burn patients: A cause or consequence of critical illness?

Citation: Expert Review of Respiratory Medicine, October 2011, vol./is. 5/5(663-673), 1747-6348;1747-6356 (October 2011) Author(s): Huzar T.F., Cross J.M.

Abstract: The article concludes that strategies directed at preventing and treating VAP in burn patients must address not only rapid extubation and VAP prevention bundles known to work in other intensive care unit populations, but therapies directed to more rapid wound healing and restoration of pulmonary patency.


 

Title: Reducing ventilator-associated pneumonia in intensive care: Impact of implementing a care bundle

Citation: Critical Care Medicine, October 2011, vol./is. 39/10(2218-2224), 0090-3493;1530-0293 (October 2011) Author(s): Morris A.C., Hay A.W., Swann D.G., Everingham K., McCulloch C., McNulty J., Brooks O., Laurenson I.F., Cook B., Walsh T.S.

Abstract: This study aimed to determine the effects of implementing such a bundle while controlling for potential confounding variables seen in similar studies.

Full Text: Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

 

Title: The trouble with studying bundles

Citation: Critical Care Medicine, October 2011, vol./is. 39/10(2355-2357), 0090-3493;1530-0293 (October 2011) Author(s): Doron S., Nasraway S.A.

Full Text: Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

Title: Attributable mortality of ventilator-associated pneumonia

Citation: Current Opinion in Critical Care, October 2011, vol./is. 17/5(464-471), 1070-5295;1531-7072 (October 2011) Author(s): Timsit J.-F., Zahar J.-R., Chevret S.

Abstract: To critically discuss the attributable mortality of ventilator-associated pneumonia (VAP) and potential sources of variation


 

Title: Is VAP really a separate entity?

Citation: Clinical Pulmonary Medicine, September 2011, vol./is. 18/5(250-251), 1068-0640;1536-5956 (September 2011) Author(s): Spiegler P.

Abstract: Synopsis: An analysis of ventilator-associated pneumonia and nonventilated, intensive care unit-associated pneumonia found the 2 to be similar and suggested that classifying pneumonia as ventilator-associated is an artificial distinction.

 


 

Title: Effect of enhanced ultraviolet germicidal irradiation in the heating ventilation and air conditioning system on ventilator-associated pneumonia in a neonatal intensive care unit

Citation: Journal of Perinatology, September 2011, vol./is. 31/9(607-614), 0743-8346;1476-5543 (September 2011) Author(s): Ryan R.M., Wilding G.E., Wynn R.J., Welliver R.C., Holm B.A., Leach C.L.

Abstract: The objective of this study was to test the hypothesis that enhanced ultraviolet germicidal irradiation (eUVGI) installed in our neonatal intensive care unit (NICU) heating ventilation and air conditioning system (HVAC) would decrease HVAC and NICU environment microbes, tracheal colonization and ventilator-associated pneumonia (VAP).


 

Title: Prevention of VAP: Is zero rate possible?

Citation: Clinics in Chest Medicine, September 2011, vol./is. 32/3(591-599), 0272-5231;1557-8216 (September 2011) Author(s): Blot S., Lisboa T., Angles R., Rello J.

Abstract: The authors discuss some of the recent evidence of the prevention of nosocomial infections, with a particular emphasis on VAP.


 

Title: Diagnosis of ventilator-associated respiratory infections (VARI): Microbiologic clues for tracheobronchitis (VAT) and pneumonia (VAP)

Citation: Clinics in Chest Medicine, September 2011, vol./is. 32/3(547-557), 0272-5231;1557-8216 (September 2011) Author(s): Craven D.E., Hudcova J., Lei Y.

Abstract: Intubated patients are at risk of bacterial colonization and ventilator-associated respiratory infection (VARI). VARI includes tracheobronchitis (VAT) or pneumonia (VAP). VAT and VAP caused by multidrug-resistant (MDR) pathogens are increasing in the United States and Europe. In patients with risk factors for MDR pathogens, empiric antibiotics are often initiated for 48 to 72 hours pending the availability of pathogen identification and antibiotic sensitivity data. Extensive data indicate that early, appropriate antibiotic therapy improves outcomes for patients with VAP. Recognizing and treating VARI may allow earlier appropriate therapy and improved patient outcomes. 2011 Elsevier Inc.


 

Title: De-escalation therapy: Is it valuable for the management of ventilator-associated pneumonia?

Citation: Clinics in Chest Medicine, September 2011, vol./is. 32/3(517-534), 0272-5231;1557-8216 (September 2011) Author(s): Niederman M.S., Soulountsi V.

Abstract:This review examines the factors associated with an effective de-escalation strategy and ways to increase the rates of de-escalation in the future.


 

Title: The tracheal tube: Gateway to ventilator-associated pneumonia

Citation: Critical Care, September 2011, vol./is. 15/5, 1364-8535;1466-609X (29 Sep 2011) Author(s): Zolfaghari P.S., Wyncoll D.L.A.

Abstract:  In this view point article, the authors explore the published data supporting the new tracheal tubes and their potential contribution to VAP prevention strategies. They also propose that it may now be against good medical practice to continue to use a 'standard cuffed tube' given what is already known, and the weight of evidence supporting the use of newer tube designs.

Full Text: Available in selected fulltext at BioMedCentral


 

Title: Early-onset ventilator-associated pneumonia incidence in intensive care units: A surveillance-based study

Citation: BMC Infectious Diseases, September 2011, vol./is. 11/, 1471-2334 (06 Sep 2011) Author(s): Vanhems P., Benet T., Voirin N., Januel J.-M., Lepape A., Allaouchiche B., Argaud L., Chassard D., Guerin C.

Abstract: The objective was to estimate early-onset VAP occurrence in ICUs within 48 hours after admission.

Full Text: Available in fulltext at EBSCO HostAvailable in fulltext at BioMedCentral

Available in fulltext at National Library of Medicine


 

Title: Effect of antibiotic diversity on ventilator-associated pneumonia caused by ESKAPE organisms

Citation: Chest, September 2011, vol./is. 140/3(643-651), 0012-3692;1931-3543 (01 Sep 2011)Author(s): Sandiumenge A., Lisboa T., Gomez F., Hernandez P., Canadell L., Rello J.

Abstract: The aim of this study was to test in the clinic whether antimicrobial diversity affects resistance of Enterococcus faecium, Staphylococcus aureus, Klebsiella species, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species (ESKAPE) pathogens in ventilator-associated pneumonia (VAP). Full Text: Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

 

 

 

 

Title: The long-term outcome of a multifaceted intervention to reduce ventilator-associated pneumonia: Can zero really be achieved?

Citation: American Journal of Infection Control, September 2011, vol./is. 39/7(613-614), 0196-6553;1527-3296 (September 2011) Author(s): Apisarnthanarak A., Warren D.K., Fraser V.J.

Full Text: Available in print at Heartlands Staff Library


 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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