Critical Care & Anaesthesia- August 2012

 

 

Critical Care & Anaesthesia – Update  

 

 


August 2012

Welcome to the August bulletin of 2012 highlighting new evidence published on selected topics relating to Critical Care, Anaesthesia, Pain and Resuscitation. This bulletin will continue in its current format following a positive evaluation by staff. Full text articles can be accessed via your HEFT Athens ID.

Anaesthesia

The following sub-topics are covered:

  • Cell salvage in surgery (including obstetric surgery)
  • Anaesthesia and surgical outcomes (including epidurals, regional anaesthesia)
  • Anaesthesia and Immunomodulation
  • Anaesthesia and post operative confusion

 

Title: Retrospective analysis of the efficacy of perioperative use of the cell salvage and autologous blood recovery system during laparoscopic myomectomy.

Citation: Archives of Gynecology & Obstetrics, April 2012, vol./is. 285/4(1073-7), 0932-0067;1432-0711 (2012 Apr) Author(s): Kumakiri J, Kikuchi I, Kitade M, Matsuoka S, Kono A, Takeda S

Abstract: PURPOSE: To evaluate the benefit of the intraoperative use of a cell salvage and autologous blood recovery system during laparoscopic myomectomy (LM).


 

Title: Cell salvage is beneficial for all cardiac surgical patients: arguments for and against.

Citation: Journal of Extra-Corporeal Technology, March 2012, vol./is. 44/1(P38-41), 0022-1058;0022-1058 (2012 Mar) Author(s): Baker RA, Merry AF

Abstract: Extensive literature has been published evaluating the use of cell salvage in cardiac surgery. However, the most recently published blood management guidelines do not give unequivocal direction on the use of cell salvage in cardiac surgical procedures and neither do recent meta-analyses and randomized controlled trials.


 

Title: A retrospective audit of anesthetic techniques and complications in children with mucopolysaccharidoses

Citation: Paediatric Anaesthesia, August 2012, vol./is. 22/8(737-744), 1155-5645;1460-9592 (August 2012) Author(s): Frawley G., Fuenzalida D., Donath S., Yaplito-Lee J., Peters H.

Abstract: The objective of the study is to document the incidence of difficult airway management and difficult intubation in the era of replacement therapy for Australian children with mucopolysaccharidosis (MPS).

Full Text: Available in full text at EBSCOhost


 

Title: Locoregional versus general anesthesia for open inguinal herniorrhaphy: A national surgical quality improvement program analysis

Citation: American Surgeon, July 2012, vol./is. 78/7(798-802), 0003-1348 (July 2012) Author(s): Bhattacharya S.D., Vaslef S.N., Pappas T.N., Scarborough J.E.

Abstract: The objective was to study outcomes associated with open inguinal herniorrhaphy performed under locoregional (LR) versus general anesthesia (GA). National Surgical Quality Improvement Program (NSQIP) data from 2005 to 2009 was queried to capture patients undergoing initial unilateral inguinal herniorrhaphy.

Full Text: Available in full text at EBSCOhost  Available in full text at ProQuest


 

Title: Consent, assent, and the importance of risk stratification

Citation: British Journal of Anaesthesia, July 2012, vol./is. 109/1(40-46), 0007-0912;1471-6771 (July 2012) Author(s): Dennehy L., White S.

Abstract: In this article, the common law of consent relating to anaesthesia is reviewed in order to highlight more recent changes to the standard of information provision and treatment of patients without capacity, and to form the basis of a critique of the current law.

Full Text: Available in full text at EBSCOhost EJS  Available in print at Solihull Staff Library


 

Title: Ephedrine Versus Phenylephrine for the Management of Hypotension During Spinal Anesthesia for Cesarean Section: An Updated Meta-Analysis

Citation: CNS Neuroscience and Therapeutics, July 2012, vol./is. 18/7(591-597), 1755-5930;1755-5949 (July 2012) Author(s): Lin F.-Q., Qiu M.-T., Ding X.-X., Fu S.-K., Li Q.

Abstract: A systematic literature review comparing the efficacy of ephedrine and phenylephrine for the management of spinal anesthesia-induced hypotension during Cesarean sections (C-sections) was published in 2002. A number of well-designed trials with controversial results have been published afterward. Therefore, an updated meta-analysis was necessary.


 

Title: The effect of intravenous magnesium therapy on the duration of intrathecal fentanyl labor analgesia

Citation: International Journal of Obstetric Anesthesia, July 2012, vol./is. 21/3(212-216), 0959-289X;1532-3374 (July 2012) Author(s): Sullivan J.T., Higgins N., Toledo P., Scavone B.M., McCarthy R.J., Wong C.A.

Abstract: The purpose of this study was to determine the influence of intravenous magnesium therapy administered for preeclampsia on the duration of intrathecal fentanyl analgesia for labor.

Full Text: Available in full text at EBSCOhost EJS  Available in full text at Elsevier; Note: You will need to register (free of charge) with Science Direct the first time you use it.


 

Title: Local or spinal anesthesia in subinguinal varicocelectomy: A prospective randomized trial

Citation: Urology, July 2012, vol./is. 80/1(9-14), 0090-4295;1527-9995 (July 2012) Author(s): Kadihasanoglu M., Karaguzel E., Kacar C.K., Arkan M.S., Yapc M.E., Turkmen N.

Abstract: To determine whether local anesthesia (LA) is an acceptable alternative to spinal anesthesia (SA) for varicocelectomy.

Full Text: Available in full text at MD Consult; Note: You will need to register (free of charge) with MD Consult the first time you use it.


 

Title: Outcomes of carotid endarterectomy under general and regional anesthesia from the American College of Surgeons' National Surgical Quality Improvement Program

Citation: Journal of Vascular Surgery, July 2012, vol./is. 56/1(81-88.e3), 0741-5214;1097-6809 (July 2012) Author(s): Leichtle S.W., Mouawad N.J., Welch K., Lampman R., Whitehouse Jr. W.M., Heidenreich M.

Abstract: The objective of this study was to investigate whether anesthesia type, either general anesthesia (GA) or regional anesthesia (RA), independently contributes to the risk of postoperative cardiovascular complications or death using the American College of Surgeons' National Surgical Quality Improvement Program (ACS NSQIP) database.

Full Text: Available in full text at Ovid


 

Title: Spinal anesthesia for noncardiac surgery in infants with congenital heart diseases

Citation: Paediatric Anaesthesia, July 2012, vol./is. 22/7(647-653), 1155-5645;1460-9592 (July 2012) Author(s): Kachko L., Birk E., Simhi E., Tzeitlin E., Freud E., Katz J.

Abstract: The objective was to compare hemodynamic parameters in infants with congenital heart disease (CHD) undergoing noncardiac surgery (NCS) under awake spinal anesthesia (SA) with controls without CHD also undergoing SA.

Full Text: Available in full text at EBSCOhost


 

Title: Effect of pre-exposure to sevoflurane on the bispectral index in women undergoing Caesarean delivery under general anaesthesia

Citation: British Journal of Anaesthesia, June 2012, vol./is. 108/6(990-997), 0007-0912;1471-6771 (June 2012) Author(s): Choi W.J., Kim S.H., Koh W.U., Hwang D.I., Cho S.K., Park P.H., Han S.M., Shin J.W.

Abstract: Patients undergoing Caesarean delivery under inhalation anaesthesia are at a high risk of awareness, especially in the period before delivery. We assessed the effects of pre-exposure to sevoflurane on the bispectral index (BIS) in the interval before delivery.

Full Text: Available in full text at EBSCOhost EJS  Available in print at Solihull Staff Library


 

Title: Multimodal periarticular injection vs continuous femoral nerve block after total knee arthroplasty. A prospective, crossover, randomized clinical trial

Citation: Journal of Arthroplasty, June 2012, vol./is. 27/6(1234-1238), 0883-5403;1532-8406 (June 2012) Author(s): Ng F.-Y., Ng J.K.F., Chiu K.-Y., Yan C.-H., Chan C.-W.

Abstract: This study compares the efficacy of pain control using continuous femoral nerve block (FNB) and multimodal periarticular soft tissue injection.


 

Title: Optimised anaesthesia to reduce post operative cognitive decline (POCD) in older patients undergoing elective surgery, a randomised controlled trial

Citation: PLoS ONE, June 2012, vol./is. 7/6, 1932-6203 (15 Jun 2012) Author(s): Ballard C., Jones E., Gauge N., Aarsland D., Nilsen O.B., Saxby B.K., Lowery D., Corbett A., Wesnes K., Katsaiti E., Arden J., Amaoko D., Prophet N., Purushothaman B., Green D.

Abstract: The study determined the one year incidence of post operative cognitive decline (POCD) and evaluated the effectiveness of an intra-operative anaesthetic intervention in reducing post-operative cognitive impairment in older adults (over 60 years of age) undergoing elective orthopaedic or abdominal surgery.

Full Text: Available in full text at National Library of Medicine


 

Title: Anesthetic management in patients undergoing hyperthermic chemotherapy

Citation: Current Opinion in Anaesthesiology, June 2012, vol./is. 25/3(348-355), 0952-7907;1473-6500 (June 2012) Author(s): Raspe C., Piso P., Wiesenack C., Bucher M.

Abstract: Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has become an important therapeutic option for selected patients with peritoneal surface malignancies. This aggressive multimodality treatment is complex, not only regarding surgical technique, but also regarding anesthesia. The present review represents the authors experience in anaesthetic care.


 

 

Title: Perioperative care for the older outpatient undergoing ambulatory surgery.

Citation: Anesthesia & Analgesia, June 2012, vol./is. 114/6(1190-215), 0003-2999;1526-7598 (2012 Jun) Author(s): White PF, White LM, Monk T, Jakobsson J, Raeder J, Mulroy MF, Bertini L, Torri G, Solca M, Pittoni G, Bettelli G

Abstract: In this review article the authors summarize the physiologic and pharmacologic effects of aging and their influence on anesthetic drugs, the important considerations in the preoperative evaluation of elderly outpatients with coexisting diseases, the advantages and disadvantages of different anesthetic techniques on a procedural-specific basis, and offer recommendations regarding the management of common postoperative side effects (including delirium and cognitive dysfunction, fatigue, dizziness, pain, and gastrointestinal dysfunction) after ambulatory surgery.

Full Text: Available in full text at Ovid


 

Title: Type of anaesthesia for hip fracture surgery - the problems of trial design.

Citation: Anaesthesia, June 2012, vol./is. 67/6(574-8), 0003-2409;1365-2044 (2012 Jun) Author(s): White SM, Griffiths R, Moppett K


 

Cardiac arrests/cardiopulmonary resuscitation (CPR)

The following sub-topics are covered:

  • Quality of CPR
  • Use of feedback devices
  • Leadership and team factors

 

Title: National standards in prehospital resuscitation training are required

Citation: Emergency Medicine Journal, July 2012, vol./is. 29/7(602), 1472-0205;1472-0213 (July 2012) Author(s): Lyon R.M., Sinclair N.

Full Text: Available in full text at Highwire Press


 

Title: Challenges of do-not-attempt-resuscitation orders: Reply

Citation: JAMA - Journal of the American Medical Association, June 2012, vol./is. 307/23(2488-2489), 0098-7484;1538-3598 (13 Jun 2012) Author(s): Blinderman C.D., Krakauer E.L., Solomon M.Z.

Full Text: Available in full text at EBSCOhost EJS; Note: Go to link "Available on Publisher's Site:"


 

Critical Care

The following sub-topics are covered:

  • Sepsis – the use of statins, biomarker MMP9
  • Acute lung injury (ALI)/adult respiratory distress syndrome (ARDS)
  • Use of non invasive ventilation (NIV) in weaning
  • Ventilator associate pneumonia (including E.Coli)

 

Title: The association of prior statin use in septic shock treated with early goal directed therapy

Citation: European Journal of Emergency Medicine, August 2012, vol./is. 19/4(226-230), 0969-9546;1473-5695 (August 2012) Author(s): Fuller B.M., Gajera M., Schorr C., Gerber D., Dellinger R.P., Zanotti S.

Abstract: To test the hypothesis that previous statin use is associated with improved clinically relevant outcomes in patients with severe sepsis and septic shock receiving EGDT.


 

Title: The effect of aspirin in transfusion-related acute lung injury in critically ill patients.

Citation: Anaesthesia, June 2012, vol./is. 67/6(594-9), 0003-2409;1365-2044 (2012 Jun)

Author(s): Tuinman PR, Vlaar AP, Binnenkade JM, Juffermans NP

Abstract: The study examined the association of aspirin use before admission to the intensive care unit and the development of transfusion-related acute lung injury in critically ill patients.


 

Title: Dexamethasone in patients with acute lung injury from acute monocytic leukaemia.

Citation: European Respiratory Journal, March 2012, vol./is. 39/3(648-53), 0903-1936;1399-3003 (2012 Mar) Author(s): Azoulay E, Canet E, Raffoux E, Lengline E, Lemiale V, Vincent F, de Labarthe A, Seguin A, Boissel N, Dombret H, Schlemmer B

Abstract: The study sought to evaluate dexamethasone in patients with ALI/ARDS caused by acute monocytic leukaemia (AML FAB-M5) via either leukostasis or leukaemic infiltration.


Title: Beta-blockers in intensive care medicine: Potential benefit in acute brain injury and acute respiratory distress syndrome

Citation: Recent Patents on Cardiovascular Drug Discovery, August 2012, vol./is. 7/2(141-151), 1574-8901 (August 2012) Author(s): van der Jagt M., Miranda D.R.

Abstract: In this review the authors describe pathophysiological considerations that may help in elucidating the potential role of beta (beta)-adrenergic antagonists to block some of the adverse sympathetic effects in acute brain injury (subarachnoid hemorrhage and traumatic brain injury) and the acute respiratory distress syndrome.


 

Title: Plasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance.

Citation: Critical Care Medicine, June 2012, vol./is. 40/6(1731-7), 0090-3493;1530-0293 (2012 Jun) Author(s): Calfee CS, Gallagher D, Abbott J, Thompson BT, Matthay MA, NHLBI ARDS Network

Abstract: The objective was to determine whether plasma angiopoietin-2 levels are associated with clinical outcomes and affected by fluid management strategy in a broad cohort of patients with acute lung injury.

Full Text: Available in full text at Ovid


 

Title: The acute respiratory distress syndrome: what's in a name?.

Citation: JAMA, June 2012, vol./is. 307/23(2542-4), 0098-7484;1538-3598 (2012 Jun 20)

Author(s): Angus DC

Full Text: Available in full text at EBSCOhost EJS; Note: Go to link "Available on Publisher's Site:"


 

Title: Acute respiratory distress syndrome: the Berlin Definition.

Citation: JAMA, June 2012, vol./is. 307/23(2526-33), 0098-7484;1538-3598 (2012 Jun 20)

Author(s): ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS

Abstract: This updated and revised Berlin Definition for ARDS addresses a number of the limitations of the AECC definition. The approach of combining consensus discussions with empirical evaluation may serve as a model to create more accurate, evidence-based, critical illness syndrome definitions and to better inform clinical care, research, and health services planning.

Full Text: Available in full text at EBSCOhost EJS; Note: Go to link "Available on Publisher's Site:"


 

Title: von Willebrand factor and angiopoietin-2: toward an acute lung injury endothelial endophenotype?.

Citation: Critical Care Medicine, June 2012, vol./is. 40/6(1966-7), 0090-3493;1530-0293 (2012 Jun) Author(s): Meyer NJ, Christie JD

Full Text: Available in full text at Ovid

Title: Ventilatory support is not as smooth as power-assisted steering--not yet.

Citation: Critical Care Medicine, June 2012, vol./is. 40/6(1968-9), 0090-3493;1530-0293 (2012 Jun) Author(s): Mols G, Guttmann J

Full Text: Available in full text at Ovid


 

Title: Neurally adjusted ventilatory assist improves patient-ventilator interaction during postextubation prophylactic noninvasive ventilation.

Citation: Critical Care Medicine, June 2012, vol./is. 40/6(1738-44), 0090-3493;1530-0293 (2012 Jun) Author(s): Schmidt M, Dres M, Raux M, Deslandes-Boutmy E, Kindler F, Mayaux J, Similowski T, Demoule A

Abstract: To compare the respective impact of pressure support ventilation and naturally adjusted ventilatory assist, with and without a non-invasive mechanical ventilation algorithm, on patient-ventilator interaction.

Full Text: Available in full text at Ovid


 

Title: Ventilator-associated pneumonia and its prevention

Citation: Current Opinion in Infectious Diseases, August 2012, vol./is. 25/4(395-404), 0951-7375;1473-6527 (August 2012) Author(s): Bouadma L., Wolff M., Lucet J.-C.

Abstract: This study provides an update on the prevention of VAP, focusing on the ability of preventive measures to improve patient outcomes and concentrating wherever possible on the data published within the past 5 years. Particular attention is being paid to the latest approach to facilitate the implementation of those prevention measures known as 'care bundles'.


 

Title: Genetic polymorphisms within tumor necrosis factor gene promoter region: A role for susceptibility to ventilator-associated pneumonia

Citation: Cytokine, August 2012, vol./is. 59/2(358-363), 1043-4666;1096-0023 (August 2012) Author(s): Kotsaki A., Raftogiannis M., Routsi C., Baziaka F., Kotanidou A., Antonopoulou A., Orfanos S.E., Katsenos C., Koutoukas P., Plachouras D., Mandragos K., Giamarellos-Bourboulis E.J.

Abstract: Debatable findings exist among various studies regarding the impact of single nucleotide polymorphisms (SNPs) within the promoter region of the tumor necrosis factor (TNF) gene for susceptibility to infections. Their impact was investigated in a cohort of mechanically ventilated patients who developed ventilator-associated pneumonia (VAP).


 

Title: Azithromycin to prevent Pseudomonas aeruginosa ventilator-associated pneumonia by inhibition of quorum sensing: A randomized controlled trial

Citation: Intensive Care Medicine, July 2012, vol./is. 38/7(1118-1125), 0342-4642;1432-1238 (July 2012) Author(s): Van Delden C., Kohler T., Brunner-Ferber F., Francois B., Carlet J., Pechere J.-C.

Abstract: The authors aimed to assess whether azithromycin could prevent VAP in patients colonized by rhamnolipids producing isolates.


 

 

 

Title: Number needed to treat and cost-effectiveness in the prevention of ventilator-associated pneumonia

Citation: Critical Care, June 2012, vol./is. 16/3, 1364-8535;1466-609X (07 Jun 2012) Author(s): Wyncoll D., Camporota L.

Full Text: Available in selected full text at BioMedCentral


 

Title: Economic burden of ventilator-associated pneumonia in a developing country

Citation: Journal of Hospital Infection, June 2012, vol./is. 81/2(128-130), 0195-6701;1532-2939 (June 2012) Author(s): Alp E., Kalin G., Coskun R., Sungur M., Guven M., Doganay M.

Abstract: Ventilator-associated pneumonia (VAP) developed in 96 (60%) of 159 patients with 37.2 cases per 1000 ventilation-days in a medical intensive care unit (MICU). Median time for VAP development was 5.5 days (range: 2-25). The most significant risk factors for VAP were stay in hospital before MICU and length of stay in MICU. The mean length of stay in MICU for VAP patients was 23.8 +/- 19.8 days, which was four-fold higher than for non-VAP patients. The daily cost for VAP patients was half that for non-VAP patients. The total costs for VAP patients were about three-fold higher than for non-VAP patients. 2012 The Healthcare Infection Society.

Full Text: Available in full text at Elsevier; Note: You will need to register (free of charge) with Science Direct the first time you use it.


 

Title: Procalcitonin in early onset ventilator-associated pneumonia

Citation: Journal of Hospital Infection, June 2012, vol./is. 81/2(92-97), 0195-6701;1532-2939 (June 2012) Author(s): Zielinska-Borkowska U., Skirecki T., Zlotorowicz M., Czarnocka B.

Abstract: The aim was to assess the clinical usefulness of monitoring PCT concentrations in non-surgical patients with early onset VAP.

Full Text: Available in full text at Elsevier; Note: You will need to register (free of charge) with Science Direct the first time you use it.


 

Title: Eight initiatives that misleadingly lower ventilator-associated pneumonia rates

Citation: American Journal of Infection Control, June 2012, vol./is. 40/5(408-410), 0196-6553;1527-3296 (June 2012) Author(s): Klompas M.

Full Text: Available in print at Heartlands Staff Library


 

Title: Treatment failure in ventilator associated pneumonia

Citation: Current Respiratory Medicine Reviews, June 2012, vol./is. 8/3(239-244), 1573-398X;1875-6387 (June 2012) Author(s): Iannella H.A., Luna C.M.

Abstract: Ventilator-associated pneumonia (VAP) is a severe, frequent and potentially fatal complication in the intensive care unit (ICU). Treatment failure (TF) in VAP is defined as the lack of improvement in clinical parameters and/or the persistence of the infecting microorganism, and is associated with a poor outcome. The prevalence of TF in VAP ranges from 30% to 62%, and there is general agreement that it is associated with increased mortality.


 

Title: Biomarkers in the diagnosis of ventilator-associated pneumonia

Citation: Current Respiratory Medicine Reviews, June 2012, vol./is. 8/3(184-192), 1573-398X;1875-6387 (June 2012) Author(s): Grover V., Soni N., Kelleher P., Singh S.

Abstract: Ventilator Associated Pneumonia (VAP) is a common nosocomial infection in the ICU. Diagnosis based on best available criteria remains difficult. Current and novel biomarkers have the potential to speed up and improve the accuracy of its diagnosis. This review highlights the markers that have gained the most attention to date and aims to discuss the challenges faced in introducing them at the bedside.


 

Title: Preventing ventilator-associated pneumonia - the role of the endotracheal tube

Citation: Current Respiratory Medicine Reviews, June 2012, vol./is. 8/3(170-183), 1573-398X;1875-6387 (June 2012) Author(s): Young P.J., Doyle A.J.

Abstract: This review appraises the role of the endotracheal tube in both the development and prevention of VAP. 2012 Bentham Science Publishers.

Title: The oral cavity, biofilms and ventilator-associated pneumonia

Citation: Current Respiratory Medicine Reviews, June 2012, vol./is. 8/3(163-169), 1573-398X;1875-6387 (June 2012) Author(s): Williams D.W., Lewis M.A.O., Marino P.J., Wise M.P.

Abstract: It is probable that the normal oral microflora is an influencing factor for VAP, either through affecting recruitment of respiratory pathogens to oral plaque, or to biofilms that develop in the endotracheal tube. Recent studies have indeed highlighted that poor oral hygiene is a risk factor for VAP and therefore the maintenance of adequate oral health care in ventilated patients represents an important preventative strategy. 2012 Bentham Science Publishers.


 

New Books Added to the HEFT Libraries

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Further Information:

The following sources have been scanned for evidence published in the previous 8 weeks: Lancet, BMJ, JAMA, NEJM and American Journal of Critical Care Medicine; and articles from other journals as retrieved via searches on MEDLINE and EMBASE are also listed.

For a detailed list of sources that have been scanned, please contact [email protected]

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