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Table of Contents
Cochrane Reviews
Bjornson, C et al (2013) Nebulized epinephrine for
croup in children. Cochrane Database of
Systematic Reviews (Online), Issue 10 pp.CD006619.
Link to Abstract Link to Full Text
Author’s Conclusions: Nebulized epinephrine is associated with clinically and statistically significant transient reduction of symptoms of croup 30 minutes post-treatment. Evidence does not favour racemic epinephrine or L-epinephrine, or IPPB over simple nebulization. The authors note that data and analyses were limited by the small number of relevant studies and total number of participants and thus most outcomes contained data from very few or even single studies.
Black, KJ et al (2013) Nerve blocks for initial pain
management of femoral fractures in children.
Cochrane Database of Systematic Reviews (Online),
Issue 12, pp.CD009587. Link to Abstract
Author’s Conclusions: Low quality evidence from one small trial suggests that FICB provides better and longer lasting pain relief with fewer adverse events than intravenous opioids for femur fractures in children. Well conducted and reported randomised trials that compare nerve blocks (both FNB and FICB) with systemic analgesia and that use validated pain scores are needed.
Brouwer, MC et al (2013) Corticosteroids for acute
bacterial meningitis. Cochrane Database of
Systematic Reviews (Online), 6, pp.CD004405.
Link to Abstract Link to Full Text
Author’s Conclusions: Corticosteroids significantly
reduced hearing loss and neurological sequelae, but
did not reduce overall mortality. Data support the use
of corticosteroids in patients with bacterial meningitis
in high-income countries. We found no beneficial
effect in low-income countries.
Burns, KE et al (2013) Noninvasive positive-
pressure ventilation as a weaning strategy for
intubated adults with respiratory failure. Cochrane
Database of Systematic Reviews (Online), 12,
pp.CD004127. Link to Abstract Link to Full Text
Author’s Conclusions: Summary estimates from 16
trials of moderate to good quality that included
predominantly participants with COPD suggest that a
weaning strategy that includes NPPV may reduce
rates of mortality and ventilator-associated
pneumonia without increasing the risk of weaning
failure or reintubation.
Cao, AM et al (2013) Chest radiographs for acute
lower respiratory tract infections. Cochrane
Database of Systematic Reviews (Online), 12,
pp.CD009119. Link to Abstract Link to Full Text
Author’s Conclusions: Data from two trials suggest
that routine chest radiography does not affect the
clinical outcomes in adults and children presenting to
a hospital with signs and symptoms suggestive of a
LRTI. This conclusion may be weakened by the risk
of bias of the studies and the lack of complete data
available.
Cates, CJ et al (2013) Regular treatment with
salmeterol and inhaled steroids for chronic
asthma: serious adverse events. Cochrane
database of systematic reviews (Online), 3,
pp.CD006922. Link to Abstract Link to Full Text
Author’s Conclusions: We found no statistically significant differences in fatal or non-fatal serious adverse events in trials in which regular salmeterol was randomly allocated with ICS, in comparison to ICS alone at the same dose. Although 13,447 adults and 1862 children have now been included in trials, the frequency of adverse events is too low and the results are too imprecise to confidently rule out a relative increase in all-cause mortality or non-fatal adverse events with salmeterol used in conjunction with ICS. However, the absolute difference between groups in the risk of serious adverse events was very small. We could not determine whether the increase in all cause non-fatal serious adverse events reported in the previous meta-analysis on regular salmeterol alone is abolished by the additional use of regular ICS. We await the results of large on going surveillance studies mandated by the FDA to provide more information. There were no asthma-related deaths and few asthma-related serious adverse events. Clinical decisions and information for patients regarding regular use of salmeterol have to take into account the balance between known symptomatic benefits of salmeterol and the degree of uncertainty and concern associated with its potential harmful effects.
Cates, CJ et al (2013) Combination formoterol and
budesonide as maintenance and reliever therapy
versus current best practice (including inhaled
steroid maintenance), for chronic asthma in
adults and children. Cochrane Database of
Systematic Reviews (Online), 4, pp.CD007313.
Link to Abstract Link to Full Text
Author’s Conclusions: Single inhaler therapy has now been demonstrated to reduce exacerbations requiring oral corticosteroids against current best practice strategies and against a fixed higher dose of inhaled steroids. The strength of evidence that SiT reduces hospitalisation against these same treatments is weak. There were more discontinuations due to adverse events on SiT compared to current best practice, but no significant differences in serious adverse events. Our confidence in these conclusions is limited by the open-label design of the trials, and by the unknown adherence to treatment in the current best practice arms of the trials.Single inhaler therapy can reduce the risk of asthma exacerbations needing oral corticosteroids in comparison with fixed dose maintenance ICS and separate relief medication. The reduced odds of exacerbations with SiT compared with higher dose ICS should be viewed in the context of the possible impact of LABA withdrawal during study run-in. This may have made the study populations more likely to respond to SiT. Single inhaler therapy is not currently licensed for children under 18 years of age in the United Kingdom and there is currently very little research evidence for this approach in children or adolescents.
Chauhan, BF et al (2013) Intermittent versus daily
inhaled corticosteroids for persistent asthma in
children and adults. Cochrane Database of
Systematic Reviews (Online), 2, pp.CD009611.
Link to Abstract Link to Full Text
Author’s Conclusions: In children and adults
with persistent asthma and in preschool children
suspected of persistent asthma, there was low quality
evidence that intermittent and daily ICS strategies
were similarly effective in the use of rescue oral
corticosteroids and the rate of severe adverse health
events. The strength of the evidence means that we
cannot currently assume equivalence between the
two options.. Daily ICS was superior to intermittent
ICS in several indicators of lung function, airway
inflammation, asthma control and reliever use. Both
treatments appeared safe, but a modest growth
suppression was associated with daily, compared to
intermittent, inhaled budesonide and
beclomethasone. Clinicians should carefully weigh
the potential benefits and harm of each treatment
option, taking into account the unknown long-term (>
one year) impact of intermittent therapy on lung
growth and lung function decline.
Chaturvedi, S et al (2014) Pharmacological
interventions for hypertension in children.
Cochrane Database of Systematic Reviews (Online),
2, pp.CD008117. Link to Abstract Link to Full Text
Author’s Conclusions: Overall, there are
sparse data informing the use of antihypertensive
agents in children, with outcomes reported limited to
blood pressure and not end organ damage. The most
data are available for candesartan, for which there is
low-quality evidence of a modest lowering effect on
blood pressure. We did not find evidence of a
consistent dose response relationship for escalating
doses of angiotensin receptor blockers, calcium
channel blockers or angiotensin-converting enzyme
inhibitors. All agents appear safe, at least in the short
term.
Davey, P et al (2013) Interventions to improve
antibiotic prescribing practices for hospital
inpatients. Cochrane Database of Systematic
Reviews (Online), 4, pp.CD003543.
Link to Abstract Link to Full Text
Author’s Conclusions: The results show that
interventions to reduce excessive antibiotic
prescribing to hospital inpatients can reduce
antimicrobial resistance or hospital-acquired
infections, and interventions to increase effective
prescribing can improve clinical outcome. This
update provides more evidence about unintended
clinical consequences of interventions and about the
effect of interventions to reduce exposure of patients
to antibiotics. The meta-analysis supports the use of
restrictive interventions when the need is urgent, but
suggests that persuasive and restrictive interventions
are equally effective after six months.
Fernandes, RM et al (2013) Glucocorticoids for
acute viral bronchiolitis in infants and young
children. Cochrane Database of Systematic Reviews,
6, pp.CD004878. Link to Abstract Link to Full Text
Author’s Conclusions: Current evidence does not support a clinically relevant effect of systemic or inhaled glucocorticoids on admissions or length of hospitalisation. Combined dexamethasone and epinephrine may reduce outpatient admissions, but results are exploratory and safety data limited. Future research should further assess the efficacy, harms and applicability of combined therapy.
Flodgren, G et al (2013) Interventions to improve +
professional adherence to guidelines for
prevention of device-related infections. Cochrane
Database of Systematic Reviews (Online), 3,
pp.CD006559. Link to Abstract Link to Full Text
Author’s Conclusions: The low to very low quality of the evidence of studies included in this review provides insufficient evidence to determine with certainty which interventions are most effective in changing professional behaviour and in what contexts. However, interventions that may be worth further study are educational interventions involving more than one active element and that are repeatedly administered over time, and interventions employing specialised personnel, who are focused on an aspect of care that is supported by evidence e.g. dentists/dental auxiliaries performing oral care for VAP prevention.
Goldenberg, JZ et al (2013) Probiotics for the
prevention of Clostridium difficile-associated
diarrhoea in adults and children. Cochrane
Database of Systematic Reviews (Online), 5,
pp.CD006095. Link to Abstract Link to Full Text
Author’s Conclusions: Based on this systematic
review and meta-analysis of 23 randomized
controlled trials including 4213 patients, moderate
quality evidence suggests that probiotics are both
safe and effective for preventing Clostridium difficile-
associated diarrhoea.
Griffiths, B et al (2013) Combined inhaled
anticholinergics and short-acting beta2-agonists
for initial treatment of acute asthma in children.
Cochrane Database of Systematic Reviews (Online),
8, pp.CD000060. Link to Abstract Link to Full Text
Author’s Conclusions: Children with an asthma
exacerbation experience a lower risk of admission to
hospital if they are treated with the combination of
inhaled SABAs plus anticholinergic versus SABA
alone. They also experience a greater improvement
in lung function and less risk of nausea and tremor.
Within this group, the findings suggested, but did not
prove, the possibility of an effect modification, where
intensity of anticholinergic treatment and asthma
severity, could be associated with greater benefit.
Further research is required to identify the
characteristics of children that may benefit from
anticholinergic use (e.g. age and asthma severity
including mild exacerbation and impending
respiratory failure) and the treatment modalities
(dose, intensity, and duration) associated with most
benefit from anticholinergic use better.
Hemila, H et al (2013) Vitamin C for preventing and
treating the common cold. Cochrane Database of
Systematic Reviews (Online), 1, pp.CD000980.
Link to Abstract Link to Full Text
Author’s Conclusions: The failure of vitamin C
supplementation to reduce the incidence of colds in
the general population indicates that routine vitamin
C supplementation is not justified, yet vitamin C may
be useful for people exposed to brief periods of
severe physical exercise. Regular supplementation
trials have shown that vitamin C reduces the duration
of colds, but this was not replicated in the few
therapeutic trials that have been carried out.
Nevertheless, given the consistent effect of vitamin C
on the duration and severity of colds in the regular
supplementation studies, and the low cost and safety,
it may be worthwhile for common cold patients to test
on an individual basis whether therapeutic vitamin C
is beneficial for them. Further therapeutic RCTs are
warranted.
Hemila, H et al (2013) Vitamin C for preventing and
treating pneumonia. Cochrane Database of
Systematic Reviews (Online), 8, pp.CD005532.
Link to Abstract Link to Full Text
Author’s Conclusions: The prophylactic use of
vitamin C to prevent pneumonia should be further
investigated in populations who have a high
incidence of pneumonia, especially if dietary vitamin
C intake is low. Similarly, the therapeutic effects of
vitamin C should be studied, especially in patients
with low plasma vitamin C levels. The current
evidence is too weak to advocate prophylactic use of
vitamin C to prevent pneumonia in the general
population. Nevertheless, therapeutic vitamin C
supplementation may be reasonable for pneumonia
patients who have low vitamin C plasma levels
because its cost and risks are low.
Jain, K et al (2013) Bronchoscopy-guided
antimicrobial therapy for cystic fibrosis. Cochrane
database of systematic reviews (Online), 12,
pp.CD009530. Link to Abstract Link to Full Text
Author’s Conclusions: This review, which only
includes a single study, shows that there is no clear
evidence to support the routine use of
bronchoalveolar lavage for the diagnosis and
management of pulmonary infection in pre-school
children with cystic fibrosis compared to the standard
practice of providing treatment based on results of
oropharyngeal culture and clinical symptoms. No
evidence was available for adult and adolescent
populations.
Kew, KM et al (2013) Combination formoterol and
budesonide as maintenance and reliever therapy
versus combination inhaler maintenance for
chronic asthma in adults and children. Cochrane
Database of Systematic Reviews (Online), 12,
pp.CD009019. Link to Abstract Link to Full Text
Author’s Conclusions: SiT reduces the
number of people having asthma exacerbations
requiring oral steroids and the number requiring
hospitalisation or an ER visit compared with fixed-
dose combination inhalers. Evidence for serious
adverse events was unclear. The mean daily dose of
inhaled corticosteroids (ICS) in SiT, including the
total dose administered with reliever use, was always
lower than that of the other combination groups. This
suggests that the flexibility in steroid administration
that is possible with SiT might be more effective than
a standard fixed-dose combination by increasing the
dose only when needed and keeping it low during
stable stages of the disease. Data for hospitalisations
alone could not be obtained, and no studies have yet
addressed this question in children younger than age
12.
Lambert, P et al (2014) Clonidine premedication
for postoperative analgesia in children. Cochrane
database of systematic reviews (Online), 1,
pp.CD009633. Link to Abstract Link to Full Text
Author’s Conclusions: There were only 11 relevant
trials studying 742 children having surgery where
premedication with clonidine was compared to
placebo or other drug treatment. Despite
heterogeneity between trials, clonidine premedication
in an adequate dosage (4 microg/kg) was likely to
have a beneficial effect on postoperative pain in
children. Side effects were minimal, but some of the
studies used atropine prophylactically with the
intention of preventing bradycardia and hypotension.
Further research is required to determine under what
conditions clonidine premedication is most effective
in providing postoperative pain relief in children.
Macgillivray, S et al (2013) Lactose avoidance for
young children with acute diarrhoea. Cochrane
Database of Systematic Reviews (Online), 10,
pp.CD005433. Link to Abstract Link to Full Text
Author’s Conclusions: In young children with
acute diarrhoea who are not predominantly breast-
fed, change to a lactose-free diet may result in earlier
resolution of acute diarrhoea and reduce treatment
failure. Diluting lactose-containing formulas may also
have some benefits but further trials are required to
have confidence in this finding. There are no trials
from low-income countries, where mortality for
diarrhoea is high, and malnutrition is more common.
Minozzi, S et al (2013) Maintenance agonist
treatments for opiate-dependent pregnant women.
Cochrane Database of Systematic Reviews (Online),
12, pp.CD006318. Link to Abstract
Author’s Conclusions: We did not find sufficient
significant differences between methadone and
buprenorphine or slow-release morphineto allow
us to conclude that one treatment is superior to
another for all relevant outcomes. While methadone
seems superior in terms of retaining patients in
treatment, buprenorphine seems to lead to less
severe neonatal abstinence syndrome. Additionally,
even though a multi-centre, international trial with
175 pregnant women has recently been completed
and its results published and included in this review,
the body of evidence is still too small to draw firm
conclusions about the equivalence of the treatments
compared. There is still a need for randomised
controlled trials of adequate sample size comparing
different maintenance treatments.
Morrow, B et al (2013) Mechanical insufflation-
exsufflation for people with neuromuscular
disorders. Cochrane Database of Systematic
Reviews (Online), 12, pp.CD010044.
Link to Abstract Link to Full Text
Author’s Conclusions: The results of this
review do not provide sufficient evidence on which to
base clinical practice as we were unable to address
important short- and long-term outcomes, including
adverse effects of MI-E. There is currently insufficient
evidence for or against the use of MI-E in people with
NMDs. Further randomised controlled clinical trials
are needed to test the safety and efficacy of MI-E.
Mutter, TC et al (2013) Hydroxyethyl starch (HES)
versus other fluid therapies: effects on kidney
function. Cochrane Database of Systematic
Reviews (Online), 7, pp.CD007594. Link to Abstract
Author’s Conclusions: The current evidence suggests
that all HES products increase the risk in AKI and
RRT in all patient populations and a safe volume of
any HES solution has yet to be determined. In most
clinical situations it is likely that these risks outweigh
any benefits, and alternate volume replacement
therapies should be used in place of HES products.
Normansell, R et al (2014) Omalizumab for asthma
in adults and children. Cochrane Database of
Systematic Reviews (Online), 1, pp.CD003559.
Link to Abstract Link to Full Text
Author’s Conclusions: Omalizumab was effective in
reducing asthma exacerbations and hospitalisations
as an adjunctive therapy to inhaled steroids and
during steroid tapering phases of clinical trials.
Omalizumab was significantly more effective than
placebo in increasing the numbers of participants
who were able to reduce or withdraw their inhaled
steroids. Omalizumab was generally well tolerated,
although more injection site reactions were seen with
omalizumab. Further assessment in paediatric
populations is necessary, as is direct double-dummy
comparison with ICS. Although subgroup analyses
suggest that participants receiving prednisolone had
better asthma control when they received
omalizumab,it remains to be tested prospectively
whether the addition of omalizumab has a
prednisolone-sparing effect. It is also not clear
whether there is a threshold level of baseline serum
IgE for optimum efficacy of omalizumab. Given the
high cost of the drug, identification of biomarkers
predictive of response is of major importance for
future research.
Osborn, DA et al (2013) Prebiotics in infants for
prevention of allergy. Cochrane database of
systematic reviews (Online), 3, pp.CD006474.
Link to Abstract Link to Full Text
Author’s Conclusions: Further research is needed
before routine use of prebiotics can be recommended
for prevention of allergy in formula fed infants. There
is some evidence that a prebiotic supplement added
to infant feeds may prevent eczema. It is unclear
whether the use of prebiotic should be restricted to
infants at high risk of allergy or may have an effect in
low risk populations; or whether it may have an effect
on other allergic diseases including asthma.
Schoot, RA et al (2013) Systemic treatments for
the prevention of venous thrombo-embolic
events in paediatric cancer patients with
tunnelled central venous catheters. Cochrane
Database of Systematic Reviews (Online), 9,
pp.CD009160. Link to Abstract Link to Full Text
Author’s Conclusions: We found no significant effects
of systemic treatments compared with no intervention
in preventing (a)symptomatic VTE in paediatric
oncology patients with CVCs. However, this could be
a result of the low number of included participants,
which resulted in low power. In one CCT, which
compared one systemic treatment with another
systemic treatment, we identified a significant
reduction in symptomatic VTE with the addition of
LMWH to AT supplementation. All studies
investigated the prevalence of major and/or minor
bleeding episodes, and none found a significant
difference between study groups. None of the studies
reported thrombocytopenia, HIT, HITT, death as a
result of VTE, removal of CVC due to VTE, CVC-
related infection or PTS among participants. On the
basis of currently available evidence, we are not able
to give recommendations for clinical practise.
Additional well-designed international RCTs are
needed to further explore the effects of systemic
treatments in preventing VTE. Future studies should
aim for adequate power with attainable sample sizes.
The incidence of symptomatic VTE is relatively low;
therefore, it might be necessary to select participants
with thrombotic risk factors or to investigate
asymptomatic VTE instead.
Spinks, A et al (2013) Antibiotics for sore throat.
Cochrane Database of Systematic Reviews (Online),
11, pp.CD000023. Link to Abstract Link to Full Text
Author’s Conclusions Antibiotics confer relative
benefits in the treatment of sore throat. However, the
absolute benefits are modest. Protecting sore throat
sufferers against suppurative and non-suppurative
complications in high-income countries requires
treating many with antibiotics for one to benefit. This
NNTB may be lower in low-income countries.
Antibiotics shorten the duration of symptoms by
about 16 hours overall.
Thanaviratananich, S et al (2013) Once or twice
daily versus three times daily amoxicillin with or
without clavulanate for the treatment of acute
otitis media. Cochrane Database of Systematic
Reviews (Online), 12, pp.CD004975. Link to Abstract
Author’s Conclusions: This review showed that the
results of using once or twice daily doses of
amoxicillin, with or without clavulanate, were
comparable with three doses for the treatment of
AOM.
Ullman, AJ et al (2013) Optimal timing for
intravascular administration set replacement.
Cochrane database of systematic reviews (Online), 9,
pp.CD003588. Link to Abstract Link to Full Text
Author’s Conclusions: Some evidence indicates that
administration sets that do not contain lipids, blood or
blood products may be left in place for intervals of up
to 96 hours without increasing the risk of infection.
Other evidence suggests that mortality increased
within the neonatal population with infrequent
administration set replacement. However, much the
evidence obtained was derived from studies of low to
moderate quality.
Uman, LS et al (2013) Psychological interventions
for needle-related procedural pain and distress in
children and adolescents. Cochrane Database of
Systematic Reviews (Online), 10, pp.CD005179.
Link to Abstract Link to Full Text
Author’s Conclusions: Overall, there is strong
evidence supporting the efficacy of distraction and
hypnosis for needle-related pain and distress in
children and adolescents, with no evidence currently
available for preparation and information or both,
combined CBT, parent coaching plus distraction,
suggestion, or virtual reality. Additional research is
needed to further assess interventions that have only
been investigated in one RCT to date (that is,
memory alteration, parent positioning plus distraction,
blowing out air, and distraction plus suggestion).
There are continuing issues with the quality of trials
examining psychological interventions for needle-
related pain and distress.
van Driel, ML et al (2013) Different antibiotic
treatments for group A streptococcal pharyngitis.
Cochrane Database of Systematic Reviews (Online),
4, pp.CD004406. Link to Abstract Link to Full Text
Author’s Conclusions: Evidence is insufficient to
show clinically meaningful differences between
antibiotics for GABHS tonsillopharyngitis. Limited
evidence in adults suggests cephalosporins are more
effective than penicillin for relapse, but the NNTB is
high. Limited evidence in children suggests
carbacephem is more effective for symptom
resolution. Data on complications are too scarce to
draw conclusions. Based on these results and
considering the low cost and absence of resistance,
penicillin can still be recommended as first choice.
Venekamp, RP et al (2013) Antibiotics for acute
otitis media in children. Cochrane Database of
Systematic Reviews (Online), 1, pp.CD000219.
Link to Abstract Link to Full Text
Author’s Conclusions: Antibiotic treatment led to a
statistically significant reduction of children with AOM
experiencing pain at two to seven days compared
with placebo but since most children (82%) settle
spontaneously, about 20 children must be treated to
prevent one suffering from ear pain at two to seven
days. Additionally, antibiotic treatment led to a
statistically significant reduction of tympanic
membrane perforations (NNTB 33) and contralateral
AOM episodes (NNTB 11). These benefits must be
weighed against the possible harms: for every 14
children treated with antibiotics, one child
experienced an adverse event (such as vomiting,
diarrhoea or rash) that would not have occurred if
antibiotics had been withheld. Antibiotics appear to
be most useful in children under two years of age
with bilateral AOM, or with both AOM and otorrhoea.
For most other children with mild disease, an
expectant observational approach seems justified.
We have no trials in populations with higher risks of
complications.
Zhang, L et al (2013) Nebulised hypertonic saline
solution for acute bronchiolitis in infants.
Cochrane Database of Systematic Reviews (Online),
7, pp.CD006458. Link to Abstract Link to Full Text
Author’s Conclusions: Current evidence suggests
nebulised 3% saline may significantly reduce the
length of hospital stay among infants hospitalised
with non-severe acute viral bronchiolitis and improve
the clinical severity score in both outpatient and
inpatient populations.
NICE Guidelines
NICE (2013) Atopic eczema in children. London:
Nice. Quality Standard QS 44. Link to Full Text
Abstract: This quality standard covers the
management of atopic eczema in children from birth
up to the age of 12 years
NICE (2013) Autism: Management of Autism in
Children and Young People. London: NICE. Clinical
Guidance CG 170. Link to Full Text
Abstract: This clinical guideline offers evidence-
based advice on the care and management of
children and young people with autism.
NICE (2013) Depression in Children and Young
People. London: NICE. Quality Standard QS 48.
Abstract: This quality standard covers the diagnosis
and management of depression in children and
young people aged between 5 and 17 years (that is,
up to their 18th birthday).
NICE (2013) Feverish Illness in Children. London:
NICE. Clinical Guidance CG 160). Link to Full Text
This clinical guideline updates and replaces NICE clinical guideline 47 (published May 2007). It offers evidence-based advice on the care of young children with feverish illness.
New and updated recommendations have been included in areas relating to assessment and initial management in children younger than 5 years with no obvious cause of feverish illness
NICE (2013) Headaches in Young People and
Adults. London: NICE. Quality Standard QS 42.
Abstract: This quality standard covers the diagnosis and management of the most common primary headache disorders (tension-type headache, migraine and cluster headache) and medication overuse headache in adults and young people aged 12 years and older
NICE (2014) Head injury: Triage, assessment, investigation and early management of head injury in children, young people and adults. London, NICE. CG 176 Link to Full Text
Abstract: This guidance partially updates and replaces NICE clinical guideline CG56. It offers evidence-based advice on the care of children, young people and adults with head injury.
NICE (2013) Managing overweight and obesity among children and young people: lifestyle weight management services. NICE. Public Health PH 47 Link to Full Text
Abstract: This guidance makes recommendations on lifestyle weight management (sometimes called tier 2) services for overweight and obese children and young people aged under 18. These services are just one part of a comprehensive approach to preventing and treating obesity.
NICE (2013) Urinary Tract Infection in Infants,
Children and Young People Under 16. London:
NICE. Quality standard QS 36 Link to Full Text
Abstract: This quality standard covers the care of infants, children and young people under 16 years with a first or recurrent upper or lower urinary tract infection and without known underlying uropathy
Reports & Statistics
Oliva, L et al 2013 Overlooked and forgotten: a
review of how well children and young people's
mental health is being prioritised in the current
commissioning landscape. CaYPsMH
London: CYPMHC. Link to Full Text
Abstract: This report offers support and
recommendations to health and wellbeing boards on
how they can prioritise and address children and
young people’s mental health. It is based on a review
of 145 joint strategic needs assessment (JSNAs) and
142 joint health and wellbeing strategies (JHWSs)
General
Adams, S et al (2013) Exploring the usefulness of
comprehensive care plans for children with
medical complexity (CMC): a qualitative study.
BMC Pediatrics, 13, pp.10. Link to Abstract
Boutis, K et al (2013) Effect of the Low Risk Ankle
Rule on the frequency of radiography in children
with ankle injuries. CMAJ : Canadian Medical
Association Journal = Journal de l'Association
Medicale Canadienne, 185 (15), pp.E731-738.
Doi: 10.1503/cmaj.122050. Link to Abstract
Brown, CC et al (2014) Making your way as an
academic paediatric trainee in the UK. Archives of
Disease in Childhood - Education & Practice Edition,
99 (1), pp.13-14. Link to Abstract Link to Full Text
Eisen, S et al (2014) Peer mentoring: evaluation of
a novel programme in paediatrics. Archives of
Disease in Childhood, 99 (2), pp.142-146.
Link to Abstract Link to Full Text
Eventov-Friedman, S et al (2014) Using a safe taxi
service to transport newborn babies home from
hospital. Acta Paediatrica, 103 (1), pp.57-61.
Ferro, MA (2014) Adolescents and young adults
with physical illness: a comparative study of
psychological distress. Acta Paediatrica, 103 (1),
pp.e32-e37. Link to Abstract
Gaab, EM et al (2014) Siblings Caring for and
about Pediatric Palliative Care Patients. Journal of
Palliative Medicine, 17 (1), pp.62-67. Link to Abstract
Goddard, JM (2014) Chronic pain in Children and
Young People. Paediatrics and Child Health, 24 (2),
pp.89-91. Link to Abstract
Hall, AE et al (2014) What ethical and legal
principles should guide the genotyping of
children as part of a personalised screening
programme for common cancer? Journal of
Medical Ethics, 40 (3), pp.163-167. Link to Abstract
Kamble, S et al (2014) The acceptability among
young Hindus and Muslims of actively ending the
lives of newborns with genetic defects. Journal of
Medical Ethics, 40 (3), pp.186-191. Link to Abstract
Klaber, RE et al (2014) Delivering quality
improvement: the need to believe it is necessary.
Archives of Disease in Childhood, 99 (2), pp.175-179.
Link to Abstract Link to Full Text
Myors, KA et al (2014) Child and family health
nurses working with families of preschool-aged
children. Journal of Clinical Nursing, 23 (1-2),
pp.181-190. Link to Abstract Link to Full Text
O'Donnell, HC et al (2014) Impact of Newborn
Follow-up Visit Timing on Subsequent ED Visits
and Hospital Readmissions: An Instrumental
Variable Analysis. Academic Pediatrics, 14 (1),
pp.84-91. Link to Abstract
O'Donnell, HC et al (2014) Factors Associated With
Timing of First Outpatient Visit After Newborn
Hospital Discharge. Academic Pediatrics, 14 (1),
pp.77-83. Link to Abstract
Pitchforth, J et al (2014) Improving the use of
phlebotomy services in a paediatric inpatient
setting. BMJ Quality Improvement Reports, 2 (2)
Sahib El-Radhi, A (2014) Determining fever in
children: the search for an ideal thermometer.
British Journal of Nursing (Mark Allen Publishing), 23
(2), pp.91-94. Link to Abstract
Simon, TD et al (2013) Quality Improvement
Research in Pediatric Hospital Medicine and the
Role of the Pediatric Research in Inpatient
Settings (PRIS) Network. Academic Pediatrics, 13
(6, Supplement), pp.S54-S60. Link to Abstract
Slopen, N et al (2014) Cumulative Adversity in
Childhood and Emergent Risk Factors for Long-
Term Health. The Journal of Pediatrics, 164 (3),
pp.631-638.e632. Link to Abstract
Soares, NS et al (2014) The Influence of
Community Access to Child Health (CATCH)
Program on Community Pediatrics. Pediatrics, 133
(1), pp.e205-e212. Link to Abstract
Vanhelst, J et al (2013) Effect of child health status
on parents' allowing children to participate in
pediatric research. BMC Medical Ethics, 14, pp.7.
Link to Abstract Link to Full Text
Wekell, P et al (2014) Devising a competency-
based continuing professional development
programme to meet the needs of on-call
consultant paediatricians. Acta Paediatrica, 103 (3),
pp.320-330. Link to Abstract
Zhang, LF et al (2014) A systematic review of the
psychometric properties of transition readiness
assessment tools in adolescents with chronic
disease. BMC Pediatrics, 14 (1), pp.4.
Link to Abstract Link to Full Text
Allergy
Anagnostou, K et al (2014) Assessing the efficacy
of oral immunotherapy for the desensitisation of
peanut allergy in children (STOP II): a phase 2
randomised controlled trial. Lancet, Online first
30th January 2014 Link to Abstract Link to Full Text
Francavilla, R et al (2014) Clinical, Serologic, and
Histologic Features of Gluten Sensitivity in
Children. The Journal of Pediatrics, 164 (3), pp.463-
467.e461. Link to Abstract
Grimshaw, KE et al (2013) Diet and food allergy
development during infancy: Birth cohort study
findings using prospective food diary data. The
Journal of Allergy and Clinical Immunology, 133 (2),
pp 511-519 Link to Abstract
Gupta, R et al (2013) The economic impact of
childhood food allergy in the United States. JAMA
Pediatrics, 167 (11), pp.1026-1031. Link to Abstract
Indinnimeo, L et al (2013) Duration of a cow-milk
exclusion diet worsens parents' perception of
quality of life in children with food allergies. BMC
Pediatrics, 13, pp.203. Link to Abstract
Jackson, J et al (2013) Cognitive and psychosocial
function post hematopoietic stem cell
transplantation in children with hemophagocytic
lymphohistiocytosis. The Journal of Allergy and
Clinical Immunology, 132 (4), pp.889-895 e881-883.
Just, J et al (2014) Childhood Allergic Asthma Is
Not a Single Phenotype. The Journal of Pediatrics,
Published on line ahead of print. Link to Abstract
Pfaar, O et al (2013) Depigmented-polymerized
mixed grass/birch pollen extract immunotherapy
is effective in polysensitized patients. Allergy, 68
(10), pp.1306-1313. Link to Abstract
Anaesthetics and Analgesia
Bredlau, AL et al (2013) Ketamine for Pain in
Adults and Children with Cancer: A Systematic
Review and Synthesis of the Literature. Pain
Medicine (Malden, Mass.), Published ahead of print
Herpertz-Dahlmann, B et al (2014) Day-patient
treatment after short inpatient care versus
continued inpatient treatment in adolescents with
anorexia nervosa (ANDI): a multicentre,
randomised, open-label, non-inferiority trial.
Lancet, Link to Abstract
Naja, ZM et al (2013) The effectiveness of
pudendal nerve block versus caudal block
anesthesia for hypospadias in children.
Anesthesia and Analgesia, 117 (6), pp.1401-1407.
Bone and Joint
McDevitt, H et al (2014) Establishing good bone
health in children. Paediatrics and Child Health, 24
(2), pp.78-82. Link to Abstract
Shrestha, D et al (2013) Systemic lupus
erythematosus and granulomatous
lymphadenopathy. BMC Pediatrics, 13, pp.179.
Link to Abstract Link to Full Text
Son, MBF et al (2014) Outcomes in Hospitalized
Pediatric Patients With Systemic Lupus
Erythematosus. Pediatrics, 133 (1), pp.e106-e113.
Cardiovascular
Aiyagari, R et al (2013) Impact of pre-stage II
hemodynamics and pulmonary artery anatomy on
12-month outcomes in the Pediatric Heart
Network Single Ventricle Reconstruction trial.
The Journal of Thoracic and Cardiovascular Surgery,
Published on line 13th December 2013
Bijlsma, MW et al (2014) Why Pediatricians Fail to
Diagnose Hypertension: A Multicenter Survey.
The Journal of Pediatrics, 164 (1), pp.173-177.e177.
Cabrera-Rego, JO et al (2014) Epicardial Fat
Thickness Correlates With Carotid Intima-Media
Thickness, Arterial Stiffness, and Cardiac
Geometry in Children and Adolescents. Pediatric
Cardiology, 35 (30), pp. 450-460 Link to Abstract
Carli, D et al (2014) VACTERL (Vertebral Defects,
Anal Atresia, Tracheoesophageal Fistula
with Esophageal Atresia, Cardiac Defects, Renal
and Limb Anomalies) Association: Disease
Spectrum in 25 Patients Ascertained for Their
Upper Limb Involvement. The Journal of Pediatrics,
164 (3), pp.458-462.e452. Link to Abstract
Dilli, D et al (2013) Treatment outcomes of infants
with cyanotic congenital heart disease treated
with synbiotics. Pediatrics, 132 (4), pp.e932-938.
Eleftheriou, D et al (2014) Vasculitis in children. 24
(2), pp.58-63. Link to Abstract
Mellion, K et al (2014) Health-Related Quality of
Life Outcomes in Children and Adolescents with
Congenital Heart Disease. The Journal of Pediatrics,
Published online 13th January 2014.
Mullett, MD et al (2014) Association between Birth
Characteristics and Coronary Disease Risk
Factors among Fifth Graders. The Journal of
Pediatrics, 164 (1), pp.78-82. Link to Abstract
Oster, ME et al (2014) Quality Improvement in
Screening for Critical Congenital Heart Disease.
The Journal of Pediatrics, 164 (1), pp.67-71.e62.
Pretty, C et al (2013) Adverse childhood
experiences and the cardiovascular health of
children: a cross-sectional study. BMC Pediatrics,
13, pp.208. Link to Abstract Link to Full Text
Raj, S et al (2014) Myocardial Dysfunction in
Pediatric Septic Shock. The Journal of Pediatrics,
164 (1), pp.72-77.e72 Link to Abstract
Studer, MA et al (2014) Newborn Pulse Oximetry
Screening to Detect Critical Congenital Heart
Disease. The Journal of Pediatrics, 164 (3), pp.505-
509.e502. Link to Abstract
Takemoto, CM et al (2014) Hospital-Associated
Venous Thromboembolism in Children: Incidence
and Clinical Characteristics. The Journal of
Pediatrics, 164 (2), pp.332-338. Link to Abstract
Uysal, F et al (2013) Congenital Anomalies of
Coronary Arteries in Children: The Evaluation of
22 Patients. Pediatric Cardiology, Published on line
12th December 2013. Link to Abstract
Werner, H et al (2014) Health-Related Quality of
Life after Open-Heart Surgery. The Journal of
Pediatrics, 164 (2), pp.254-258.e251. Link to Abstract
Williams, DM et al (2013) Associations of maternal
25-hydroxyvitamin D in pregnancy with offspring
cardiovascular risk factors in childhood and
adolescence: findings from the Avon
Longitudinal Study of Parents and Children. Heart
(British Cardiac Society), 99 (24), pp.1849-1856.
Link to Abstract Link to Full Text
Child Development
Bleakley, A et al (2014) Violent Film Characters’
Portrayal of Alcohol, Sex, and Tobacco-Related
Behaviors. Pediatrics, 133 (1), pp.71-77.
Link to Abstract Link to Full Text
Foli, KJ et al (2014) "Great expectations" of
adoptive parents: theory extension through
structural equation modeling. Nursing Research,
63 (1), pp.14-25. Link to Abstract
Ghassabian, A et al (2014) Early lexical
development and risk of verbal and nonverbal
cognitive delay at school age. Acta Paediatrica,
103 (1), pp.70-80. Link to Abstract
Hedenbro, M et al (2014) Early interaction between
infants and their parents predicts social
competence at the age of four. Acta Paediatrica,
103 (3), pp.268-274. Link to Abstract
Lee, HS et al (2013) The impact of the use of
antiepileptic drugs on the growth of children.
BMC Pediatrics, 13, pp.211. Link to Abstract
Luby, J et al (2013) The effects of poverty on
childhood brain development: the mediating
effect of caregiving and stressful life events.
JAMA Pediatrics, 167 (12), pp.1135-1142.
Sim, F et al (2013) Language and social/
emotionalproblems identified at a universal
developmental assessment at 30 months. BMC
Pediatrics, 13, pp.206. Link to Abstract
Vohr, BR et al (2014) The importance of language
in the home for school-age children with
permanent hearing loss. Acta Paediatrica, 103 (1),
pp.62-69. Link to Abstract Link to Full Text
Wong, SC et al (2014) The Prevalence of Turner
Syndrome in Girls Presenting with Coarctation of
the Aorta. The Journal of Pediatrics, 164 (2), pp.259-
263. Link to Abstract
Child Protection
Bailhache, M et al (2013) Is early detection of
abused children possible?: a systematic review
of the diagnostic accuracy of the identification
of abused children. BMC Pediatrics, 13, pp.202.
Doi: 10.1186/1471-2431-13-202. Link to Abstract
Foa, EB et al (2013) Prolonged exposure vs
supportive counseling for sexual abuse-related
PTSD in adolescent girls: a randomized clinical
trial. JAMA: the Journal of the American Medical
Association, 310 (24), pp.2650-2657.
Robertson, BD et al (2014) At-Risk Children of At-
Risk Parents: Assessing Common Injuries to
the Children of Teenage Parents. The Journal of
Pediatrics, 164 (2), pp.347-351.e341.
Ybarra, ML et al (2013) Prevalence rates of male
and female sexual violence perpetrators in a
national sample of adolescents. JAMA Pediatrics,
167 (12), pp.1125-1134. Links to Abstract
Emergency & High Dependency
Bohman, K et al (2014) Long-term medical
consequences for child occupants 0 to 12 years
injured in car crashes. Traffic Injury Prevention, 15
(4), pp.370-378. Link to Abstract
Cunningham, RM et al (2014) Characteristics of
Youth Seeking Emergency Care for Assault
Injuries. Pediatrics, 133 (1), pp.e96-e105.
Fedewa, MV et al (2014) Exercise and Insulin
Resistance in Youth: A Meta-Analysis. Pediatrics,
133 (1), pp.e163-e174. Link to Abstract
Hartling, L et al (2013) Music to reduce pain and
distress in the pediatric emergency department: a
randomized clinical trial. JAMA Pediatrics, 167 (9),
pp.826-835. Link to Abstract
Karbuz, A et al (2014) The Use of Colistin in
Critically Ill Children in a Pediatric Intensive Care
Unit. The Pediatric Infectious Disease Journal, 33 (1),
pp.e19-e24 Link to Abstract
Macias, CG (2013) Quality Improvement in
Pediatric Emergency Medicine. Academic
Pediatrics, 13 (6, Supplement), pp.S61-S68.
Macrae, D et al (2014) A randomized trial of
hyperglycemic control in pediatric intensive care.
The New England Journal of Medicine, 370 (2),
pp.107-118. Link to Abstract
Martino, F et al (2013) Hypertension in children
and adolescents attending a lipid clinic. European
Journal of Pediatrics, 172 (12), pp.1573-1579.
O’Neil, J et al (2014) Ambulance Transport of
Noncritical Children: Emergency Medical Service
Providers’ Knowledge, Opinions, and Practice.
Clinical Pediatrics, 53 (3), pp.250-255.
Roussak, P (2014) Centralisation of paediatric
intensive care and a 24-hour retrieval service.
British Journal of Nursing (Mark Allen Publishing), 23
(1), pp.25-29. Link to Abstract
Sacco Casamassima, M et al (2014) Use of risk
stratification indices to predict mortality in
critically ill children. European Journal Pediatrics,
173 (1), pp.1-13. Link to Abstract
Saxby, C et al (2014) Managing human factors in
the assembly of the paediatric bronchoscope.
BMJ Quality Improvement Reports, 2 (2)
Stickney, CA et al (2014) Family Participation
during Intensive Care Unit Rounds: Attitudes and
Experiences of Parents and Healthcare Providers
in a Tertiary Pediatric Intensive Care Unit. The
Journal of Pediatrics, 164 (2), pp.402-406.e404.
Sznajder, M et al (2013) Depressive symptoms
among teenagers in the emergency department:
prevalence estimate and concordance with
parental perceptions. European Journal Pediatrics,
172 (12), pp.1587-1596. Link to Abstract
Wang, GS et al (2014) Unintentional Pediatric
Exposures to Central Alpha-2 Agonists Reported
to the National Poison Data System. The Journal
of Pediatrics, 164 (1), pp.149-152. Link to Abstract
Wang, J et al (2014) Isotonic Versus Hypotonic
Maintenance IV Fluids in Hospitalized Children: A
Meta-Analysis. Pediatrics, 133 (1), pp.105-113.
Westergren, H et al (2014) First evaluation of the
paediatric version of the Swedish rapid
emergency triage and treatment system shows
good reliability. Acta Paediatrica, 103 (3), pp.305-
308. Link to Abstract
Endocrine & Diabetes
Aversa, T et al (2013) In young patients with
Turner or Down syndrome Graves' disease
presentation is often preceded by Hashimoto's
thyroiditis. Thyroid: Official Journal of the American
Thyroid Association, Published on line 29th January.
Cho, YH et al (2014) Puberty as an accelerator for
diabetes complications. Pediatric Diabetes, 15 (1),
pp.18-26. Link to Abstract
Fedewa, MV et al (2014) Exercise and insulin
resistance in youth: a meta-analysis. Pediatrics,
133 (1), pp.e163-174. Link to Abstract
Lyons, SK et al (2014) Transfer from pediatric to
adult health care: effects on diabetes outcomes.
Pediatric Diabetes, 15 (1), pp.10-17. Link to Abstract
Manios, Y et al (2014) Female sex, small size at
birth and low family income increase the
likelihood of insulin resistance in late childhood:
the Healthy Growth Study. Pediatric Diabetes, 15
(1), pp.41-50. Link to Abstract
Moreno-Castilla, C et al (2013) Low-carbohydrate
diet for the treatment of gestational diabetes
mellitus: a randomized controlled trial. Diabetes
Care, 36 (8), pp.2233-2238. Link to Abstract
Ng, SM et al (2014) Review of insulin treatment in
stress-related hyperglycaemia in children without
preexisting diabetes. Acta Paediatrica, 103 (1),
pp.6-9. Link to Abstract
Olausson, EA et al (2014) A Small Particle Size
Diet Reduces Upper Gastrointestinal Symptoms
in Patients With Diabetic Gastroparesis: A
Randomized Controlled Trial. The American
Journal of Gastroenterology, Published on line 14th
January. Link to Abstract
Pugliese, A et al (2014) The Juvenile Diabetes
Research Foundation Network for Pancreatic
Organ Donors with Diabetes (nPOD) Program:
goals, operational model and emerging findings.
Pediatric Diabetes, 15 (1), pp.1-9. Link to Full Text
Rosenbaum, M et al (2013) Racial/ethnic
differences in clinical and biochemical type 2
diabetes mellitus risk factors in children. Obesity
(Silver Spring, Md.), 21 (10), pp.2081-2090.
Sundberg, F et al (2014) Detection and treatment
efficacy of hypoglycemic events in the everyday
life of children younger than 7 yr. Pediatric
Diabetes, 15 (1), pp.34-40. Link to Abstract
Ear, Nose and Throat
Ahn, JH et al (2013) Outcomes of cochlear
implantation in children with CHARGE syndrome.
Acta oto-laryngologica, 133 (11), pp.1148-1153.
Benoit, MM et al (2013) The presentation and
management of mandibular tumors in the
pediatric population. The Laryngoscope, 123 (8),
pp.2035-2042. Link to Abstract
Bush, ML et al (2014) Delays in Diagnosis of
Congenital Hearing Loss in Rural Children. The
Journal of Pediatrics, 164 (2), pp.393-397.
Chang, R-KR et al (2014) Genetic Variants for
Long QT Syndrome among Infants and Children
from a Statewide Newborn Hearing Screening
Program Cohort. The Journal of Pediatrics, 164 (3),
pp.590-595.e593. Link to Abstract
Hopper, SM et al (2013) Topical Lidocaine to
Improve Oral Intake in Children With Painful
Infectious Mouth Ulcers: A Blinded, Randomized,
Placebo-Controlled Trial. Annals of Emergency
Medicine, 63 (3), pp. 292-299. Link to Abstract
Klingenberg, C et al (2014) Patient comfort during
treatment with heated humidified high flow nasal
cannulae versus nasal continuous positive
airway pressure: a randomised cross-over trial.
Archives of Disease in Childhood - Fetal and
Neonatal Edition, 99 (2), pp.F134-F137.
Link to Abstract Link to Full Text
Kutz, JW, Jr. et al (2013) Ciprofloxacin 0.3% +
dexamethasone 0.1% for the treatment for otitis
media. Expert Opinion on Pharmacotherapy, 14 (17),
pp.2399-2405. Link to Abstract
Lang, M et al (2013) A Systematic Review and
Meta-analysis of Endoscopic Balloon Dilation of
Pediatric Subglottic Stenosis. Otolaryngology –
head and neck surgery: official journal of American
Academy of Otolaryngology-Head and Neck
Surgery,150 (2), pp. 174-179 Link to Abstract
Lourenco, CB et al (2013) Child, neglect and oral
health. BMC Pediatrics, 13, pp.188. Link to Abstract
Marom, T et al (2014) Trends in otitis media-
related health care use in the United States, 2001-
2011. JAMA Pediatrics, 168 (1), pp.68-75.
Morimoto, N et al (2013) Gorham-Stout syndrome
affecting the temporal bone with cerebrospinal
fluid leakage. International Journal of Pediatric
Otorhinolaryngology, 77 (9), pp.1596-1600.
Shaikh, N et al (2014) Predicting Response to
Antimicrobial Therapy in Children with Acute
Sinusitis. The Journal of Pediatrics, 164 (3), pp.536-
541. Link to Abstract
Gastroenterology
Agha, BS et al (2013) Rare-earth magnet
ingestion: a childhood danger reaches
adolescence. Pediatric Emergency Care
29 (10), pp.1116-1118. Link to Abstract
Anabrees, J et al (2013) Probiotics for infantile
colic: a systematic review. BMC Pediatrics, 13,
pp.186. Link to Abstract Link to Full Text
Freedman, SB et al (2014) Pediatric Abdominal
Radiograph Use, Constipation, and Significant
Misdiagnoses. The Journal of Pediatrics, 164 (1),
pp.83-88.e82. Link to Abstract
Jericho, H et al (2014) Nausea Predicts Delayed
Gastric Emptying in Children. The Journal of
Pediatrics, 164 (1), pp.89-92. Link to Abstract
Lazzerini, M et al (2013) Effect of thalidomide on
clinical remission in children and adolescents
with refractory Crohn disease: a randomized
clinical trial. JAMA : the Journal of the American
Medical Association, 310 (20), pp.2164-2173.
Mercer, DF et al (2014) Serial Transverse
Enteroplasty Allows Children with Short Bowel to
Wean from Parenteral Nutrition. The Journal of
Pediatrics, 164 (1), pp.93-98. Link to Abstract
Naji, H et al (2013) Use of Surgisis for Abdominal
Wall Reconstruction in Children with Abdominal
Wall Defects. European Journal of Pediatric
Surgery: Official Journal of Austrian Association of
Pediatric Surgery, 24 (1), pp. 94-96. Link to Abstract
Ohsawa, I et al (2013) Leukocytosis and high
hematocrit levels during abdominal attacks of
hereditary angioedema. BMC Gastroenterology, 13,
pp.123. Link to Abstract Link to Full Text
Rosen, R (2014) Gastroesophageal Reflux in
Infants: More Than Just a pHenomenon. JAMA
Pediatrics, 168 (1), pp.83-89. Link to Abstract
Sarker, SA et al (2013) Anti-rotavirus protein
reduces stool output in infants with diarrhea: a
randomized placebo-controlled trial.
Gastroenterology, 145 (4), pp.740-748 e748.
Saucier, A et al (2014) Prospective Evaluation of a
Clinical Pathway for Suspected Appendicitis.
Pediatrics, 133 (1), pp.e88-e95. Link to Abstract
Sung, V et al (2013) Probiotics to Prevent or Treat
Excessive Infant Crying: Systematic Review and
Meta-analysis. JAMA Pediatrics, 167 (12), pp.1150-
1157. Link to Abstract.
Szajewska, H et al (2014) Meta-analysis shows
limited evidence for using Lactobacillus
acidophilus LB to treat acute gastroenteritis in
children. Acta Paediatrica, 103 (3), pp.249-255.
Tappin, D et al (2013) Development of an early
nurse led intervention to treat children referred to
secondary paediatric care with constipation with
or without soiling. BMC Pediatrics, 13, pp.193.
Link to Abstract Link to Full Text
Toporowska-Kowalska, E et al (2013) Diagnosis of
gastroesophageal reflux and anti-reflux
procedures among Polish children with
gastrostomies: a 10-year nationwide analysis.
European Journal of Clinical Nutrition, 67 (11),
pp.1169-1174. Link to Abstract Link to Full Text
Tsiountsioura, M et al (2014) Detailed assessment
of nutritional status and eating patterns in
children with gastrointestinal diseases attending
an outpatients clinic and contemporary healthy
controls. European Journal of Clinical Nutrition,
Published online 15th January. Link to Abstract
Wang, L et al (2013) Selective endoscopic ligation
for treatment of upper gastrointestinal
protuberant lesions. World Journal of
Gastroenterology: WJG, 19 (33), pp.5581-5585.
Link to Abstract Link to Full Text
Waugh, N et al (2013) Faecal calprotectin testing
for differentiating amongst inflammatory and
non-inflammatory bowel diseases: systematic
review and economic evaluation. Health
Technology Assessment (Winchester, England), 17
(55), pp.xv-xix, 1-211. Link to Abstract
Whyte, LA et al (2014) Coeliac disease is more
common in children with high socio-economic
status. Acta Paediatrica, 103 (3), pp.289-294.
Wu, F-Y et al (2013) Long-term Outcome After
Percutaneous Endoscopic Gastrostomy in
Children. Pediatrics & Neonatology, 54 (5), pp.326-
329. Link to Abstract
Haematology
Ezenwosu, OU et al (2013) Determinants of
academic performance in children with sickle cell
anaemia. BMC Pediatrics, 13, pp.189.
Link to Abstract Link to Full Text
Fraser, C et al (2013) Open-label Bendamustine
Monotherapy for Pediatric Patients With
Relapsed or Refractory Acute Leukemia: Efficacy
and Tolerability. Journal of Pediatric Hematology/
Oncology, Published on line31st October 2013
Goldman, RD et al (2013) Intravenous magnesium
sulfate for vaso-occlusive episodes in sickle cell
disease. Pediatrics, 132 (6), pp.e1634-1641.
Jackson, J et al (2013) Cognitive and psychosocial
function post hematopoietic stem cell
transplantation in children with hemophagocytic
lymphohistiocytosis. The Journal of Allergy and
Clinical Immunology, 132 (4), pp.889-895 e881-883.
Lagunju, IA et al (2013) Chronic blood transfusion
for primary and secondary stroke prevention in
Nigerian children with sickle cell disease: a 5-
year appraisal. Pediatric Blood & Cancer, 60 (12),
pp.1940-1945. Link to Abstract
Ridefelt, P et al (2014) Estimating reliable
paediatric reference intervals in clinical
chemistry and haematology. Acta Paediatrica, 103
(1), pp.10-15. Link to Abstract
Sazawal, S et al (2014) Efficiency of red cell
distribution width in identification of children
aged 1-3 years with iron deficiency anemia
against traditional hematological markers. BMC
Pediatrics, 14 (1), pp.8. Link to Abstract
Uijterschout, L et al (2013) Prevalence and Risk
Factors of Iron Deficiency in Healthy Young
Children in the Southwestern Region of the
Netherlands. Journal of Pediatric Gastroenterology
and Nutrition, 58 (2), pp. 195-200. Link to Abstract
Vitagliano, O et al (2013) The Bcl-2/Bax and
Ras/Raf/MEK/ERK signaling pathways:
implications in pediatric leukemia pathogenesis
and new prospects for therapeutic approaches.
Expert Review of Hematology, 6 (5), pp.587-597.
Immunology & Immunisation
Albright, K et al (2014) Provider Attitudes Toward
Public-Private Collaboration to Improve
Immunization Reminder/Recall: A Mixed-Methods
Study. Academic Pediatrics, 14 (1), pp.62-70.
Arnheim-Dahlstrom, L et al (2013) Autoimmune,
neurological, and venous thromboembolic
adverse events after immunisation of adolescent
girls with quadrivalent human papillomavirus
vaccine in Denmark and Sweden: cohort study.
BMJ (Clinical research ed.), 347, pp.f5906.
Link to Abstract Link to Full Text
Glanz, JM et al (2013) Association between
undervaccination with diphtheria, tetanus toxoids,
and acellular pertussis (DTaP) vaccine and risk of
pertussis infection in children 3 to 36 months of
age. JAMA Pediatrics, 167 (11), pp.1060-1064.
Halperin, SA et al (2014) Safety and
Immunogenicity of a Toddler Dose Following an
Infant Series of a Hexavalent Diphtheria, Tetanus,
Acellular Pertussis, Inactivated Poliovirus,
Haemophilus influenzae Type b, Hepatitis B
Vaccine Administered Concurrently or at
Separate Visits With a Heptavalent
Pneumococcal Conjugate Vaccine. The Pediatric
Infectious Disease Journal, 33 (1), pp.73-80
Hollm-Delgado, M-G et al (2014) Acute Lower
Respiratory Infection Among Bacille Calmette-
Guérin (BCG)–Vaccinated Children. Pediatrics,
133 (1), pp.e73-e81. Link to Abstract
Holman, DM et al (2014) Barriers to Human
Papillomavirus Vaccination Among US
Adolescents: A Systematic Review of the
Literature. JAMA Pediatrics, 168 (1), pp.76-82.
Jain, VK et al (2013) Vaccine for prevention of mild
and moderate-to-severe influenza in children. The
New England Journal of Medicine, 369 (26), pp.2481-
2491. Link to Abstract
Lee, P-I et al (2013) Recommendations for
Rotavirus Vaccine. Pediatrics & Neonatology, 54 (6),
pp.355-359. Link to Abstract
Opel, DJ et al (2013) The relationship between
parent attitudes about childhood vaccines survey
scores and future child immunization status: a
validation study. JAMA Pediatrics, 167 (11),
pp.1065-1071. Link to Abstract
Prymula, R et al (2014) Protection against varicella
with two doses of combined measles-mumps-
rubella-varicella vaccine versus one dose of
monovalent varicella vaccine: a multicentre,
observer-blind, randomised, controlled trial.
Lancet, Published online 29th January
Rowhani-Rahbar, A et al (2013) Effect of age on the
risk of Fever and seizures following immunization
with measles-containing vaccines in children.
JAMA Pediatrics, 167 (12), pp.1111-1117.
Tom, JO et al (2014) Personal Health Record Use
and Association with Immunizations and Well-
Child Care Visits Recommendations. The Journal
of Pediatrics, 164 (1), pp.112-117. Link to Abstract
Infant Feeding
Badiee, Z et al (2013) The Calming Effect of
Maternal Breast Milk Odor on Premature Infants.
Pediatrics & Neonatology, 54 (5), pp.322-325.
Bevan, G et al (2014) Interventions in exclusive
breastfeeding: a systematic review. British Journal
of Nursing (Mark Allen Publishing), 23 (2), pp.86-89.
Bonuck, K et al (2014) Bottle-Weaning Intervention
and Toddler Overweight. The Journal of Pediatrics,
164 (2), pp.306-312.e302. Link to Abstract
Brown, A et al (2013) Breastfeeding is associated
with a maternal feeding style low in control from
birth. PloS One, 8 (1), pp.e54229. Link to Abstract
Chang, J-C et al (2013) Influence of Prolonged
Storage Process, Pasteurization, and Heat
Treatment on Biologically-active Human Milk
Proteins. Pediatrics & Neonatology, 54 (6), pp.360-
366. Link to Abstract
Emond, A et al (2013) Randomised controlled trial
of early frenotomy in breastfed infants with mild-
moderate tongue-tie. Archives of Disease in
Childhood. Fetal and Neonatal Edition, Published
online 18th November. Link to Full Text
Gaffney, KF et al (2014) Postpartum Depression,
Infant Feeding Practices, and Infant Weight Gain
at Six Months of Age. Journal of Pediatric Health
Care: Official Publication of National Association of
Pediatric Nurse Associates & Practitioners, 28 (1),
pp.43-50. Link to Abstract
Gibbs, BG et al (2014) Breastfeeding, Parenting,
and Early Cognitive Development. The Journal of
Pediatrics, 164 (3), pp.487-493. Link to Abstract
Hawkins, SS et al (2014) Compliance with the
Baby-Friendly Hospital Initiative and impact on
breastfeeding rates. Archives of Disease in
Childhood - Fetal and Neonatal Edition, 99 (2),
pp.F138-F143. Link to Abstract Link to Full Text
Hill, GD et al (2014) Feeding Dysfunction in
Children with Single Ventricle Following Staged
Palliation. The Journal of Pediatrics, 164 (2),
pp.243-246.e241. Link to Abstract
Howe, LD et al (2013) Trajectories of
socioeconomic inequalities in health, behaviours
and academic achievement across childhood and
adolescence. Journal of Epidemiology and
community health, 67 (4), pp. 358-364
Link to Abstract Link to Full Text
Hwang, Y-S et al (2013) Associations Among
Perinatal Factors and Age of Achievement of Full
Oral Feeding in Very Preterm Infants. Pediatrics &
Neonatology, 54 (5), pp.309-314. Link to Abstract
Jonsdottir, OH et al (2014) Exclusive breastfeeding
for 4 versus 6 months and growth in early
childhood. Acta Paediatrica, 103 (1), pp.105-111.
Lambert, LM et al (2014) Variation in Feeding
Practices following the Norwood Procedure. The
Journal of Pediatrics, 164 (2), pp.237-242.e231.
Leite, ME et al (2013) Calcium and fat metabolic
balance, and gastrointestinal tolerance in term
infants fed milk-based formulas with and without
palm olein and palm kernel oils: a randomized
blinded crossover study. BMC Pediatrics, 13,
pp.215. Link to Abstract Link to Full Text
Maas, C et al (2013) Early feeding of fortified
breast milk and in-hospital-growth in very
premature infants: a retrospective cohort
analysis. BMC Pediatrics, 13, pp.178.
Link to Abstract Link to Full Text
Martin, RM et al (2013) Effects of promoting
longer-term and exclusive breastfeeding on
adiposity and insulin-like growth factor-I at age
11.5 years: a randomized trial. JAMA: the Journal
of the American Medical Association, 309 (10),
pp.1005-1013. Link to Abstract Link to Full Text
Northrup, TF et al (2013) Breastfeeding practices
in mothers of high-respiratory-risk NICU infants:
impact of depressive symptoms and smoking.
Journal of Maternal-Fetal and Neonatal Medicine, 26
(18), pp.1838-1843. Link to Abstract
Ross, PA et al (2014) Accuracy of Pulse Oximetry
in Children. Pediatrics, 133 (1), pp.22-29.
Szajewska, H et al (2013) Growth of infants fed
formula supplemented with Bifidobacterium
lactis Bb12 or Lactobacillus GG: a systematic
review of randomized controlled trials. BMC
Pediatrics, 13, pp.185. Link to Abstract
Zhang, L et al (2014) Breast feeding and
immunoprophylaxis efficacy of mother-to-child
transmission of hepatitis B virus. Journal of
Maternal-Fetal and Neonatal Medicine, 27 (2),
pp.182-186. Link to Abstract
Learning Disabilities
Alcoba, G et al (2013) Do children with
uncomplicated severe acute malnutrition need
antibiotics? A systematic review and meta-
analysis. PloS One, 8 (1), pp.e53184.
Link to Abstract Link to Full Text
Al-Owain, M et al (2013) Autism spectrum disorder
in a child with propionic acidemia. JIMD reports, 7,
pp.63-66. Link to Abstract Link to Full Text
Aversa, T et al (2013) In young patients with
Turner or Down syndrome Graves' disease
presentation is often preceded by Hashimoto's
thyroiditis. Thyroid: Official journal of the American
Thyroid Association, Published on line 29th January.
Bueno, JAS et al (2013) New contingent sequential
screening model for Down syndrome based on
the combined test associated with modified
genetic sonography. Journal of Maternal-Fetal and
Neonatal Medicine, 26 (18), pp.1792-1798.
Christensen, J et al (2013) Prenatal valproate
exposure and risk of autism spectrum disorders
and childhood autism. JAMA: the Journal of the
American Medical Association, 309 (16), pp.1696-
1703. Link to Abstract.
Imamura, T et al (2013) Neurodevelopmental
Outcomes of Children with Periventricular
Leukomalacia. Pediatrics & Neonatology, 54 (6),
pp.367-372. Link to Abstract
King, BH et al (2013) Baseline factors predicting
placebo response to treatment in children and
adolescents with autism spectrum disorders: a
multisite randomized clinical trial. JAMA Pediatrics,
167 (11), pp.1045-1052. Link to Abstract
Kotte, A et al (2013) Autistic traits in children with
and without ADHD. Pediatrics, 132 (3), pp.e612-622.
Kuzniewicz, MW et al (2014) Prevalence and
Neonatal Factors Associated with Autism
Spectrum Disorders in Preterm Infants. The
Journal of Pediatrics, 164 (1), pp.20-25.
McCabe, J et al (2013) Nursing, sexual health and
youth with disabilities: a critical ethnography.
Journal of Advanced Nursing, 70 (1), pp. 77-86
Link to Abstract Link to Full Text
Polo-Kantola, P et al (2014) Obstetric Risk Factors
and Autism Spectrum Disorders in Finland. The
Journal of Pediatrics, 164 (2), pp.358-365.
Rance, G et al (2014) The Use of Listening
Devices to Ameliorate Auditory Deficit in
Children with Autism. The Journal of Pediatrics,
164 (2), pp.352-357. Link to Abstract
Robins, DL et al (2014) Validation of the Modified
Checklist for Autism in Toddlers, Revised With
Follow-up (M-CHAT-R/F). Pediatrics, 133 (1), pp.37-
45. Link to Abstract
Silva, D et al (2014) Environmental Risk Factors
by Gender Associated With Attention-
Deficit/Hyperactivity Disorder. Pediatrics, 133 (1),
pp.e14-e22. Link to Abstract
Wong, HS et al (2014) Evaluation of Early
Childhood Social-Communication Difficulties in
Children Born Preterm Using the Quantitative
Checklist for Autism in Toddlers. The Journal of
Pediatrics, 164 (1), pp.26-33.e21. Link to Abstract
Zonfrillo, MR et al (2014) Residual Cognitive
Disability after Completion of Inpatient
Rehabilitation among Injured Children. The
Journal of Pediatrics, 164 (1), pp.130-135.
Mental Health
Chemtob, CM et al (2013) Maternal posttraumatic
stress disorder and depression in pediatric
primary care: association with child maltreatment
and frequency of child exposure to traumatic
events. JAMA Pediatrics, 167 (11), pp.1011-1018.
Duffy, A et al (2013) The developmental trajectory
of bipolar disorder. The British Journal of
Psychiatric: the Journal of Mental Science, 204 (2),
pp. 122-128 Link to Abstract
Hodgkinson, S et al (2014) Addressing the Mental
Health Needs of Pregnant and Parenting
Adolescents. Pediatrics, 133 (1), pp.114-122.
Kassam-Adams, N et al (2013) Posttraumatic
stress following pediatric injury: update on
diagnosis, risk factors, and intervention. JAMA
Pediatrics, 167 (12), pp.1158-1165. Link to Abstract
Marsac, ML et al (2013) Preventing posttraumatic
stress following pediatric injury: a randomized
controlled trial of a web-based psycho-
educational intervention for parents. Journal of
Pediatric Psychology, 38 (10), pp.1101-1111.
Miranda, R et al (2014) Longitudinal follow-up
study of adolescents who report a suicide
attempt: aspects of suicidal behavior that
increase risk of a future attempt. Depression and
anxiety, 31 (1), pp.19-26. Link to Abstract
Syurina, EV et al (2014) Family history of mental1
conditions in the preventive paediatric primary
care: is it really used? Case of the Netherlands.
Acta Paediatrica, 103 (3), pp.309-313.
Venkatesh, KK et al (2014) Accuracy of Brief
Screening Tools for Identifying Postpartum
Depression Among Adolescent Mothers.
Pediatrics, 133 (1), pp.e45-e53. Link to Abstract
Metabolic Disorders
Dai, S et al (2014) Non−High-Density Lipoprotein
Cholesterol: Distribution and Prevalence of High
Serum Levels in Children and Adolescents:
United States National Health and Nutrition
Examination Surveys, 2005-2010. The Journal of
Pediatrics, 164 (2), pp.247-253. Link to Abstract
Koyama, S et al (2014) Adiposity Rebound and the
Development of Metabolic Syndrome. Pediatrics,
133 (1), pp.e114-e119. Link to Abstract
Martin, RM et al (2014) Effects of promoting
longer-term and exclusive breastfeeding on
cardiometabolic risk factors at age 11.5 years: a
cluster-randomized, controlled trial. Circulation,
129 (3), pp.321-329. Link to Abstract
Staiano, AE et al (2014) Cardiometabolic Risk
Factors and Fat Distribution in Children and
Adolescents. The Journal of Pediatrics, 164 (3),
pp.560-565. Link to Abstract
Nephrology
Bansal, D et al (2013) Comparison of Pediatric
Robotic-assisted Laparoscopic
Nephroureterectomy and Laparoendoscopic
Single-site Nephroureterectomy. Urology,83 (2),
pp. 438-442 Link to Abstract
Bonadio, W (2013) Urinary Tract Infection in
Outpatient Febrile Infants Younger than 30 Days
of Age: A 10-Year Evaluation. Pediatric Infectious
Disease Journal, Published online 7th October 2013,
Camargo, M et al (2014) Growth of children with
end-stage renal disease undergoing daily
hemodialysis. Pediatric Nephrology, 29 (3), pp.439-
444. Link to Abstract
Dingemann, C et al (2013) Laparoscopic
transperitoneal heminephrectomy for duplex
kidney in infants and children: a comparative
study. Journal of Laparoendoscopic & Advanced
Surgical Techniques. Part A, 23 (10), pp.889-893.
Filler, G et al (2014) Methods of assessing renal
function. Pediatric Nephrology, 29 (2), pp.183-192.
Gandhi, S et al (2013) Calcium-channel blocker-
clarithromycin drug interactions and acute
kidney injury. JAMA: the Journal of the American
Medical Association, 310 (23), pp.2544-2553.
Garcia-Bello, J et al (2014) Carotid intima media
thickness, oxidative stress, and inflammation in
children with chronic kidney disease. Pediatric
Nephrology, 29 (2), pp.273-281. Link to Abstract
Gunasekara, V et al (2014) C1q nephropathy in
children: clinical characteristics and outcome.
Pediatric Nephrology, 29 (3), pp.407-413.
Hanley, H et al (2014) Identifying Potential Kidney
Donors Among Newborns Undergoing
Circulatory Determination of Death. Pediatrics,
133 (1), pp.e82-e87. Link to Abstract
Ho, J et al (2014) Proteomics in acute kidney
injury—current status and future promise.
Pediatric Nephrology, 29 (2), pp.163-171.
Humes, HD et al (2014) The bioartificial kidney:
current status and future promise. Pediatric
Nephrology, 29 (3), pp.343-351. Link to Abstract
Kida, Y et al (2014) Peritubular capillary
rarefaction: a new therapeutic target in chronic
kidney disease. Pediatric Nephrology, 29 (3),
pp.333-342. Link to Abstract
Laakkonen, H et al (2014) Parent–child and
spousal relationships in families with a young
child with end-stage renal disease. Pediatric
Nephrology, 29 (2), pp.289-295. Link to Abstract
Mangera, A et al (2013) An Updated Systematic
Review and Statistical Comparison of
Standardised Mean Outcomes for the Use of
Botulinum Toxin in the Management of Lower
Urinary Tract Disorders. European Urology,
Published online 1st November. Link to Abstract
Megged, O (2014) Staphylococcus aureus urinary
tract infections in children are associated with
urinary tract abnormalities and vesico-ureteral
reflux. Pediatric Nephrology, 29 (2), pp.269-272.
Mitsnefes, M et al (2014) Ceramides and cardiac
function in children with chronic kidney disease.
Pediatric Nephrology, 29 (3), pp.415-422.
Ozkan, H et al (2013) Culture-proven neonatal
sepsis in preterm infants in a neonatal intensive
care unit over a 7-year period: Coagulase-
negative Staphylococcus as the predominant
pathogen. Pediatrics International: Official Journal of
the Japan Pediatric Society, 56 (1) Link to Abstract
Siomou, E et al (2014) Growth and function in
childhood of a normal solitary kidney from birth
or from early infancy. Pediatric Nephrology, 29 (2),
pp.249-256. Link to Abstract
Sung, J et al (2013) Alemtuzumab induction with
tacrolimus monotherapy in 25 pediatric renal
transplant recipients. Pediatric Transplantation, 17
(8), pp.718-725. Link to Abstract
Symons, J (2014) Moving beyond supportive
care—current status of specific therapies in
pediatric acute kidney injury. Pediatric Nephrology,
29 (2), pp.173-181. Link to Abstract
Tancredi, DJ et al (2014) Pretransplant Serum
Albumin Is an Independent Predictor of Graft
Failure in Pediatric Renal Transplant Recipients.
The Journal of Pediatrics, 164 (3), pp.602-606.
Watson, L et al (2014) Urine biomarkers for
monitoring juvenile lupus nephritis: a
prospective longitudinal study. Pediatric
Nephrology, 29 (3), pp.397-405. Link to Abstract
Woolf, A et al (2014) Genetics of human congenital
urinary bladder disease. Pediatric Nephrology, 29
(3), pp.353-360. Link to Abstract
Neurology
Dagalakis, U et al (2014) Puberty and Plexiform
Neurofibroma Tumor Growth in Patients with
Neurofibromatosis Type I. The Journal of Pediatrics,
164 (3), pp.620-624. Link to Abstract
Gray, N et al (2014) The effect of continuous
intrathecal baclofen on sitting in children with
severe cerebral palsy. European Journal of
Paediatric Neurology, 18 (1), pp.45-49.
Grønborg, S et al (2014) Mortality and causes of
death in children referred to a tertiary epilepsy
center. European Journal of Paediatric Neurology,
18 (1), pp.66-71. Link to Abstract
Grosso, S et al (2014) Efficacy and safety of
lacosamide in infants and young children with
refractory focal epilepsy. European Journal of
Paediatric Neurology, 18 (1), pp.55-59.
Mankinen, K et al (2014) Neuropsychological
performance in children with temporal lobe
epilepsy having normal MRI findings. European
Journal of Paediatric Neurology, 18 (1), pp.60-65.
Musselman, KE et al (2013) Prevalence of ataxia in
children: A systematic review. Neurology, 82 (1),
pp. 80-89 Link to Abstract
Porto, L et al (2014) Conventional magnetic
resonance imaging in the differentiation between
high and low-grade brain tumours in paediatric
patients. European Journal of Paediatric Neurology,
18 (1), pp.25-29. Link to Abstract
Powers, SW et al (2013) Cognitive behavioral
therapy plus amitriptyline for chronic migraine in
children and adolescents: a randomized clinical
trial. JAMA: the Journal of the American Medical
Association, 310 (24), pp.2622-2630. Link to Abstract
Ramantani, G et al (2014) Epilepsy in Aicardi–
Goutières syndrome. European Journal of
Paediatric Neurology, 18 (1), pp.30-37.
Risen, SR et al (2014) Functional Outcomes in
Children with Abusive Head Trauma Receiving
Inpatient Rehabilitation Compared with Children
with Nonabusive Head Trauma. The Journal of
Pediatrics, 164 (3), pp.613-619.e612. Link to Abstract
Romaniello, R et al (2013) A Novel Mutation in
STXBP1 Gene in a Child With Epileptic
Encephalopathy and an Atypical Electroclinical
Pattern. Journal of Child Neurology, 29 (2), pp.
249-253 Link to Abstract
Sakzewski, L et al (2014) Efficacy of Upper Limb
Therapies for Unilateral Cerebral Palsy: A Meta-
analysis. Pediatrics, 133 (1), pp.e175-e204.
Link to Abstract Link to Full Text
Sánchez Fernández, I et al (2014) Electrographic
Seizures after Convulsive Status Epilepticus in
Children and Young Adults: A Retrospective
Multicenter Study. The Journal of Pediatrics, 164
(2), pp.339-346.e332. Link to Abstract
Sarrazin, E et al (2014) Growth and psychomotor
development of patients with Duchenne muscular
dystrophy. European Journal of Paediatric
Neurology, 18 (1), pp.38-44. Link to Abstract
Tsai, M-C et al (2014) Mood Disorders after
Traumatic Brain Injury in Adolescents and Young
Adults: A Nationwide Population-Based Cohort
Study. The Journal of Pediatrics, 164 (1), pp.
136-141.e131. Link to Abstract
Verrotti, A et al (2014) Valproate in adolescents
with photosensitive epilepsy with generalized
tonic–clonic seizures only. European Journal of
Paediatric Neurology, 18 (1), pp.13-18.
Zotter, S et al (2013) Neuropsychological profile of
children after an episode of neuroborreliosis.
Neuropediatrics, 44 (6), pp.346-353. Link to Abstract
Nutrition, Diet & Obesity
Abreu, S et al (2014) Relationship of milk intake
and physical activity to abdominal obesity among
adolescents. Pediatric Obesity, 9 (1), pp.71-80.
Alcoba, G et al (2013) Do children with
uncomplicated severe acute malnutrition need
antibiotics? A systematic review and meta-
analysis. PloS One, 8 (1), pp.e53184.
Link to Abstract Link to Full Text
Atkinson, MA et al (2014) Vitamin D, Race, and
Risk for Anemia in Children. The Journal of
Pediatrics, 164 (1), pp.153-158.e151.
Chandler-Laney, PC et al (2014) Gut hormone
activity of children born to women with and
without gestational diabetes. Pediatric Obesity, 9
(1), pp.53-62. Link to Abstract
Cuenca-García, M et al (2014) More Physically
Active and Leaner Adolescents Have Higher
Energy Intake. The Journal of Pediatrics, 164 (1),
pp.159-166.e152. Link to Abstract
Feskanich, D et al (2014) Milk consumption during
teenage years and risk of hip fractures in older
adults. JAMA Pediatrics, 168 (1), pp.54-60.
Haines, J et al (2013) Healthy Habits, Happy
Homes: randomized trial to improve household
routines for obesity prevention among preschool-
aged children. JAMA Pediatrics, 167 (11), pp.1072-
1079. Link to Abstract
Hannon, TS et al (2014) Morning Blood Pressure Is
Associated with Sleep Quality in Obese
Adolescents. The Journal of Pediatrics, 164 (2),
pp.313-317. Link to Abstract
Hendrie, G et al (2013) Change in the family food
environment is associated with positive dietary
change in children. The International Journal of
Behavioral Nutrition and Physical Activity, 10, pp.4.
Link to Abstract Link to Full Text
Hollinghurst, S et al (2014) Cost and effectiveness
of treatment options for childhood obesity.
Pediatric Obesity, 9 (1), pp.e26-e34.
Kjölhede, EA et al (2014) Overweight and obese
children have lower cortisol levels than normal
weight children. Acta Paediatrica, 103 (3), pp.295-
299. Link to Abstract
Kokkvoll, A et al (2014) Single versus multiple-
family intervention in childhood overweight-
Finnmark Activity School: a randomised trial.
Archives of Disease in Childhood, 99 (3), pp.225-231.
Link to Abstract Link to Full Text
Low, M et al (2013) Effects of daily iron
supplementation in primary-school-aged
children: systematic review and meta-analysis of
randomized controlled trials. CMAJ : Canadian
Medical Association Journal = journal de
l'Association Medicale Canadienne, 185 (17),
pp.E791-802. Link to Abstract Link to Full Text
Maggio, AB et al (2013) BMI changes in children
and adolescents attending a specialized
childhood obesity center: a cohort study. BMC
Pediatrics, 13, pp.216. Link to Abstract
Mareno, N (2014) Parental perception of child
weight: a concept analysis. Journal of Advanced
Nursing, 70 (1), pp. 34-45 Link to Abstract
McDonagh, MS et al (2013) Systematic Review of
the Benefits and Risks of Metformin in Treating
Obesity in Children Aged 18 Years and Younger.
JAMA Pediatrics, 168 (2), pp. 178-184.
Morandi, A et al (2014) Screening for impaired
glucose tolerance in obese children and
adolescents: a validation and implementation
study. Pediatric Obesity, 9 (1), pp.17-25.
Neyestani, TR et al (2013) Calcium-vitamin D-
fortified milk is as effective on circulating bone
biomarkers as fortified juice and supplement but
has less acceptance: a randomised controlled
school-based trial. Journal of Human Nutrition and
Dietetics : the official journal of the British Dietetic
Association, Published Online 25th November
Nyaradi, A et al (2013) Diet in the early years of life
influences cognitive outcomes at 10 years: a
prospective cohort study. Acta Paediatrica, 102
(12), 1165-1173 Link to Abstract.
Schroth, RJ et al (2013) Vitamin D status of
children with severe early childhood caries: a
case-control study. BMC Pediatrics, 13, pp.174.
Link to Abstract Link to Full Text
Schusterova, I et al (2014) Epicardial adipose
tissue and cardiometabolic risk factors in
overweight and obese children and adolescents.
Pediatric Obesity, 9 (1), pp.63-70. Link to Abstract
Steinberg, N et al (2013) The effect of a weight
management program on postural balance in
obese children. European Journal of Pediatrics, 172
(12), pp.1619-1626. Link to Abstract
Timmermans, SH et al (2014) Maternal smoking
during pregnancy and childhood overweight and
fat distribution: the KOALA Birth Cohort Study.
Pediatric Obesity, 9 (1), pp.e14-e25. Link to Abstract
Tognon, G et al (2013) Mediterranean diet,
overweight and body composition in children
from eight European countries: Cross-sectional
and prospective results from the IDEFICS study.
Nutrition, Metabolism, and Cardiovascular Diseases:
NMCD, 24 (2), pp. 205-213 Link to Abstract
Veses, AM et al (2014) Physical fitness,
overweight and the risk of eating disorders in
adolescents. The AVENA and AFINOS studies.
Pediatric Obesity, 9 (1), pp.1-9. Link to Abstract
Wansink, B et al (2014) Larger Bowl Size Increases
the Amount of Cereal Children Request,
Consume, and Waste. The Journal of Pediatrics,
164 (2), pp.323-326. Link to Abstract
Zegers, D et al (2014) Screening for genetic
variants in BDNF that contribute to childhood
obesity. Pediatric Obesity, 9 (1), pp.36-42.
Oncology
Caselli, D et al (2014) Single-Day
Trimethoprim/Sulfamethoxazole Prophylaxis for
Pneumocystis Pneumonia in Children with
Cancer. The Journal of Pediatrics, 164 (2), pp.
389-392.e381. Link to Abstract
Ferrari, A et al (2014) Cutaneous Melanoma in
Children and Adolescents: The Italian Rare
Tumors in Pediatric Age Project Experience. The
Journal of Pediatrics, 164 (2), pp.376-382.e372.
Hedén, L et al (2014) Effect of high-dose
paracetamol on needle procedures in children
with cancer – a RCT. Acta Paediatrica, 103 (3),
pp.314-319. Link to Abstract
Stary, J et al (2014) Intensive Chemotherapy for
Childhood Acute Lymphoblastic Leukemia:
Results of the Randomized Intercontinental Trial
ALL IC-BFM 2002. Journal of Clinical Oncology:
Official Journal of the American Society of Clinical
Oncology, 32 (3), pp.174-184. Link to Abstract
Wu, LM et al (2013) Evaluating the acceptability
and efficacy of a psycho-educational intervention
for coping and symptom management by
children with cancer: a randomized controlled
study. Journal of Advanced Nursing, Published
Online 23rd December Link to Abstract
Pharmacology & Therapeutics
Hersh, AL et al (2014) Linezolid Use in
Hospitalized Children. The Pediatric Infectious
Disease Journal, 33 (1), pp.e14-e18
Shah, R et al (2014) Communicating Doses of
Pediatric Liquid Medicines to Parents/Caregivers:
A Comparison of Written Dosing Directions on
Prescriptions with Labels Applied by Dispensed
Pharmacy. The Journal of Pediatrics, 164 (3),
pp.596-601.e591. Link to Abstract
Star, K et al (2014) Pharmacovigilance for
Children's Sake. Drug Safety: an International
Journal of Medical Toxicology and Drug Experience,
37 (2), pp.91-98. Link to Abstract
Valkhoff, VE et al (2013) Population-based
analysis of non-steroidal anti-inflammatory drug
use among children in four European countries in
the SOS project: what size of data platforms and
which study designs do we need to assess safety
issues? BMC Pediatrics, 13, pp.192. Link to Abstract
Yang, M et al (2013) Revisiting the Safety of Over-
the-Counter Cough and Cold Medications in the
Pediatric Population. Clinical Pediatrics, 53 (4), pp.
326-230. Link to Abstract
Reproduction & Sexual Health
Asheer, S et al (2014) Engaging Pregnant and
Parenting Teens: Early Challenges and Lessons
Learned From the Evaluation of Adolescent
Pregnancy Prevention Approaches. The Journal of
Adolescent Health: Official Publication of the Society
for Adolescent Medicine, 54 (3), pp.S84-S91.
Link to Abstract Link to Full Text
Farb, AF et al (2014) From Mission to Measures:
Performance Measure Development for a Teen
Pregnancy Prevention Program. The Journal of
Adolescent Health: Official Publication of the Society
for Adolescent Medicine, 54 (3), pp.S15-S20.
Harrison, K et al (2014) Sexual health in young
people with connective tissue disorders.
Paediatrics and Child Health, 24 (2), pp.72-77.
Kappeler, EM et al (2014) Historical Context for the
Creation of the Office of Adolescent Health and
the Teen Pregnancy Prevention Program. The
Journal of Adolescent Health: Official Publication of
the Society for Adolescent Medicine, 54 (3), pp.S3-
S9. Link to Abstract Link to Full Text
Kelsey, M et al (2014) Implementing Three
Evidence-Based Program Models: Early Lessons
From the Teen Pregnancy Prevention Replication
Study. The Journal of Adolescent Health: Official
Publication of the Society for Adolescent Medicine,
54 (3), pp.S45-S52. Link to Abstract
Layzer, C et al (2014) A Peer Education Program:
Delivering Highly Reliable Sexual Health
Promotion Messages in Schools. The Journal of
Adolescent Health: Official Publication of the Society
for Adolescent Medicine, 54 (3), pp.S70-S77.
Link to Abstract Link to Full Text
Respiratory Disorders
Accinelli, RA et al (2014) Adherence to reduced-
polluting biomass fuel stoves improves
respiratory and sleep symptoms in children. BMC
Pediatrics, 14 (1), pp.12. Link to Abstract
Afsharpaiman, S et al (2013) Respiratory
difficulties and breathing disorders in
achondroplasia. Paediatric Respiratory Reviews, 14
(4), pp.250-255. Link to Abstract
Akenroye, AT et al (2014) Impact of a Bronchiolitis
Guideline on ED Resource Use and Cost: A
Segmented Time-Series Analysis. Pediatrics, 133
(1), pp.e227-e234. Link to Abstract
Alansari, K et al (2013) Oral dexamethasone for
bronchiolitis: a randomized trial. Pediatrics, 132
(4), pp.e810-816. Link to Abstract.
Albuali, WH (2014) The use of intravenous and
inhaled magnesium sulphate in management of
children with bronchial asthma. Journal of
Maternal-Fetal and Neonatal Medicine, Published
on line 30th January. Link to Abstract
Bekhof, J et al (2014) Systematic review:
Insufficient validation of clinical scores for the
assessment of acute dyspnoea in wheezing
children. Paediatric Respiratory Reviews, 15 (1),
pp.98-112. Link to Abstract
Borckink, I et al (2014) Infants with severe
respiratory syncytial virus needed less ventilator
time with nasal continuous airways pressure then
invasive mechanical ventilation. Acta Paediatrica,
103 (1), pp.81-85. Link to Abstract
Briana, DD et al (2013) Small for gestational age
birth weight: impact on lung structure and
function. Paediatric Respiratory Reviews, 14 (4),
pp.256-262. Link to Abstract
Britto, MT et al (2014) Improving Outcomes for
Underserved Adolescents With Asthma. Pediatrics,
133 (2), pp.e418-e427. Link to Abstract
Cardinale, F et al (2013) Community-acquired
pneumonia in children. Early Human Development,
89, pp.S49-S52. Link to Abstract
Carraro, S et al (2013) Bronchopulmonary
dysplasia: The earliest and perhaps the longest
lasting obstructive lung disease in humans. Early
Human Development, 89, pp.S3-S5. Link to Abstract
Catanzaro, T et al (2014) Somatic Growth and
Lung Function in Sickle Cell Disease. Paediatric
Respiratory Reviews, 15 (1), pp.28-32.
Cazzato, S et al (2013) Interstitial lung disease in
children. Early Human Development, 89, pp.S39-
S43. Link to Abstract
Chen, JS et al (2013) Simple aspiration and
drainage and intrapleural minocycline
pleurodesis versus simple aspiration and
drainage for the initial treatment of primary
spontaneous pneumothorax: an open-label,
parallel-group, prospective, randomised,
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Coclite, E et al (2013) Congenital and perinatal
cytomegalovirus lung infection. Journal of
Maternal-Fetal and Neonatal Medicine, 26 (17),
pp.1671-1675. Link to Abstract
Cossette, B et al (2013) Impact of maternal use of
asthma-controller therapy on perinatal outcomes.
Thorax, 68 (8), pp.724-730. Link to Abstract
Crider, KS et al (2013) Prenatal folic acid and risk
of asthma in children: a systematic review and
meta-analysis. The American Journal of Clinical
Nutrition, 98 (5), pp.1272-1281. Link to Abstract
Fouzas, S et al (2014) Volumetric Capnography in
Infants with Bronchopulmonary Dysplasia. The
Journal of Pediatrics, 164 (2), pp.283-288.e283.
Harju, M et al (2014) The Burden of Childhood
Asthma and Late Preterm and Early Term Births.
The Journal of Pediatrics, 164 (2), pp.295-299.e291.
Hollams, EM et al (2013) Persistent Effects of
Maternal Smoking during Pregnancy on Lung
Function and Asthma in Adolescents. American
Journal of Respiratory and Critical Care Medicine,
189 4), pp. 401-407 Link to Abstract
Jacobs, JD et al (2014) 7% Hypertonic Saline in
Acute Bronchiolitis: A Randomized Controlled
Trial. Pediatrics, 133 (1), pp.e8-e13. Link to Abstract
Jang, J et al (2013) Trends in cost and outcomes
among adult and pediatric patients with asthma:
2000-2009. Annals of Allergy, Asthma &
Immunology: Official Publication of the American
College of Allergy, Asthma, & Immunology, 111 (6),
pp.516-522. Link to Abstract
Kantar, A et al (2013) Chronic cough in preschool
children. Early Human Development, 89, pp.S19-
S24. Link to Abstract
Kenyon, CC et al (2014) Rehospitalization for
Childhood Asthma: Timing, Variation, and
Opportunities for Intervention. The Journal of
Pediatrics, 164 (2), pp.300-305. Link to Abstract
Koumbourlis, AC (2014) Lung Function in Sickle
Cell Disease. Paediatric Respiratory Reviews, 15 (1),
pp.33-37. Link to Abstract
Lee, S et al (2013) Tracheobronchomalacia in
infants: The use of non-breath held 3D CT
bronchoscopy. Pediatric Pulmonology, Published
Online 25th October. Link to Abstract
Little, P et al (2013) Ibuprofen, paracetamol, and
steam for patients with respiratory tract
infections in primary care: pragmatic randomised
factorial trial. BMJ (Clinical research ed.), 347,
pp.f6041. Link to Abstract Link to Full Text
Lodge, CJ et al (2014) Early-Life Risk Factors for
Childhood Wheeze Phenotypes in a High-Risk
Birth Cohort. The Journal of Pediatrics, 164 (2),
pp.289-294.e282. Link to Abstract
Massie, J et al (2013) Cystic Fibrosis Carrier
Screening. Paediatric Respiratory Reviews, 14 (4),
pp.270-275. Link to Abstract
Mattes, J et al (2014) Prenatal origins of
bronchiolitis: protective effect of optimised
asthma management during pregnancy. Thorax,
69 (4), pp. 383-384. Link to Abstract
McBride, JJ et al (2014) Hypnosis in Paediatric
Respiratory Medicine. Paediatric Respiratory
Reviews, 15 (1), pp.82-85. Link to Abstract
Mikalsen, IB et al (2014) Blood eosinophil counts
during bronchiolitis are related to bronchial
hyper-responsiveness and lung function in early
adolescence. Acta Paediatrica, 103 (1), pp.86-92.
Norman, G et al (2013) Omalizumab for the
treatment of severe persistent allergic asthma: a
systematic review and economic evaluation.
Health Technology Assessment (Winchester,
England), 17 (52), pp.1-342. Link to Abstract
Papenburg, J et al (2013) Host and viral factors
affecting clinical performance of a rapid
diagnostic test for respiratory syncytial virus in
hospitalized children. The Journal of Pediatrics,
163 (3), pp.911-913. Link to Abstract
Parikh, K et al (2014) Bronchiolitis Management
Before and After the AAP Guidelines. Pediatrics,
133 (1), pp.e1-e7. Link to Abstract
Pavone, M et al (2013) Non-invasive positive
pressure ventilation in children. Early Human
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Powell, CV et al (2013) MAGNEsium Trial In
Children (MAGNETIC): a randomised, placebo-
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asthma in children. Health Technology Assessment
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Queen, MA et al (2014) Comparative Effectiveness
of Empiric Antibiotics for Community-Acquired
Pneumonia. Pediatrics, 133 (1), pp.e23-e29.
Ringholz, F et al (2014) Managing End Stage Lung
Disease in Children. Paediatric Respiratory
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Rotzén-Östlund, M et al (2014) Children with
multiple viral respiratory infections are older than
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pp.100-104. Link to Abstract Link to Full Text
Rubin, BK (2014) Cystic fibrosis: Myths. mistakes,
and dogma. Paediatric Respiratory Reviews, 15 (1),
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Tappenden, P et al (2013) Colistimethate sodium
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the treatment of chronic Pseudomonas
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Tsai, K-S et al (2013) Childhood Tuberculosis:
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pp.295-302. Link to Abstract
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Former Preterm, Very Low Birth Weight
Children with Bronchopulmonary Dysplasia: A
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Woodcock, A et al (2013) Efficacy and safety of
fluticasone furoate/vilanterol compared with
fluticasone propionate/salmeterol combination in
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Zahran, HS et al (2014) Assessing asthma severity
among children and adults with current asthma.
The Journal of Asthma: Official Journal of the
Association for the Care of Asthma, Published
Online 6th March. Link to Abstract
Zomer-Kooijker, K et al (2014) Lack of Long-term
Effects of High-dose Inhaled Beclomethasone for
Respiratory Syncytial Virus Bronchiolitis: A
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Rheumatology Disorders
Aggarwal, R et al (2013) Predictors of clinical
improvement in rituximab-treated refractory adult
and juvenile dermatomyositis and adult
polymyositis. Arthritis and Rheumatism, 66 (3), pp.
740-749 Link to Abstract
Armon, K (2014) Outcomes for Juvenile idiopathic
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Nistala, K et al (2013) Update in juvenile myositis.
Current Opinion in Rheumatology, 25 (6), pp.742-746.
Sudden Infant Death
Colson, ER et al (2013) Trends and factors
associated with infant bed sharing, 1993-2010:
the National Infant Sleep Position Study. JAMA
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Huang, Y et al (2013) Influence of bedsharing
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Putnam-Hornstein, E et al (2014) A Prospective
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Table of Contents
Emergency & High Dependency. 10
Pharmacology & Therapeutics. 20
Reproduction & Sexual Health. 20
Cochrane Reviews
Bjornson, C et al (2013) Nebulized epinephrine for
croup in children. Cochrane Database of
Systematic Reviews (Online), Issue 10 pp.CD006619.
Link to Abstract Link to Full Text
Author’s Conclusions: Nebulized epinephrine is associated with clinically and statistically significant transient reduction of symptoms of croup 30 minutes post-treatment. Evidence does not favour racemic epinephrine or L-epinephrine, or IPPB over simple nebulization. The authors note that data and analyses were limited by the small number of relevant studies and total number of participants and thus most outcomes contained data from very few or even single studies.
Black, KJ et al (2013) Nerve blocks for initial pain
management of femoral fractures in children.
Cochrane Database of Systematic Reviews (Online),
Issue 12, pp.CD009587. Link to Abstract
Author’s Conclusions: Low quality evidence from one small trial suggests that FICB provides better and longer lasting pain relief with fewer adverse events than intravenous opioids for femur fractures in children. Well conducted and reported randomised trials that compare nerve blocks (both FNB and FICB) with systemic analgesia and that use validated pain scores are needed.
Brouwer, MC et al (2013) Corticosteroids for acute
bacterial meningitis. Cochrane Database of
Systematic Reviews (Online), 6, pp.CD004405.
Link to Abstract Link to Full Text
Author’s Conclusions: Corticosteroids significantly
reduced hearing loss and neurological sequelae, but
did not reduce overall mortality. Data support the use
of corticosteroids in patients with bacterial meningitis
in high-income countries. We found no beneficial
effect in low-income countries.
Burns, KE et al (2013) Noninvasive positive-
pressure ventilation as a weaning strategy for
intubated adults with respiratory failure. Cochrane
Database of Systematic Reviews (Online), 12,
pp.CD004127. Link to Abstract Link to Full Text
Author’s Conclusions: Summary estimates from 16
trials of moderate to good quality that included
predominantly participants with COPD suggest that a
weaning strategy that includes NPPV may reduce
rates of mortality and ventilator-associated
pneumonia without increasing the risk of weaning
failure or reintubation.
Cao, AM et al (2013) Chest radiographs for acute
lower respiratory tract infections. Cochrane
Database of Systematic Reviews (Online), 12,
pp.CD009119. Link to Abstract Link to Full Text
Author’s Conclusions: Data from two trials suggest
that routine chest radiography does not affect the
clinical outcomes in adults and children presenting to
a hospital with signs and symptoms suggestive of a
LRTI. This conclusion may be weakened by the risk
of bias of the studies and the lack of complete data
available.
Cates, CJ et al (2013) Regular treatment with
salmeterol and inhaled steroids for chronic
asthma: serious adverse events. Cochrane
database of systematic reviews (Online), 3,
pp.CD006922. Link to Abstract Link to Full Text
Author’s Conclusions: We found no statistically significant differences in fatal or non-fatal serious adverse events in trials in which regular salmeterol was randomly allocated with ICS, in comparison to ICS alone at the same dose. Although 13,447 adults and 1862 children have now been included in trials, the frequency of adverse events is too low and the results are too imprecise to confidently rule out a relative increase in all-cause mortality or non-fatal adverse events with salmeterol used in conjunction with ICS. However, the absolute difference between groups in the risk of serious adverse events was very small. We could not determine whether the increase in all cause non-fatal serious adverse events reported in the previous meta-analysis on regular salmeterol alone is abolished by the additional use of regular ICS. We await the results of large on going surveillance studies mandated by the FDA to provide more information. There were no asthma-related deaths and few asthma-related serious adverse events. Clinical decisions and information for patients regarding regular use of salmeterol have to take into account the balance between known symptomatic benefits of salmeterol and the degree of uncertainty and concern associated with its potential harmful effects.
Cates, CJ et al (2013) Combination formoterol and
budesonide as maintenance and reliever therapy
versus current best practice (including inhaled
steroid maintenance), for chronic asthma in
adults and children. Cochrane Database of
Systematic Reviews (Online), 4, pp.CD007313.
Link to Abstract Link to Full Text
Author’s Conclusions: Single inhaler therapy has now been demonstrated to reduce exacerbations requiring oral corticosteroids against current best practice strategies and against a fixed higher dose of inhaled steroids. The strength of evidence that SiT reduces hospitalisation against these same treatments is weak. There were more discontinuations due to adverse events on SiT compared to current best practice, but no significant differences in serious adverse events. Our confidence in these conclusions is limited by the open-label design of the trials, and by the unknown adherence to treatment in the current best practice arms of the trials.Single inhaler therapy can reduce the risk of asthma exacerbations needing oral corticosteroids in comparison with fixed dose maintenance ICS and separate relief medication. The reduced odds of exacerbations with SiT compared with higher dose ICS should be viewed in the context of the possible impact of LABA withdrawal during study run-in. This may have made the study populations more likely to respond to SiT. Single inhaler therapy is not currently licensed for children under 18 years of age in the United Kingdom and there is currently very little research evidence for this approach in children or adolescents.
Chauhan, BF et al (2013) Intermittent versus daily
inhaled corticosteroids for persistent asthma in
children and adults. Cochrane Database of
Systematic Reviews (Online), 2, pp.CD009611.
Link to Abstract Link to Full Text
Author’s Conclusions: In children and adults
with persistent asthma and in preschool children
suspected of persistent asthma, there was low quality
evidence that intermittent and daily ICS strategies
were similarly effective in the use of rescue oral
corticosteroids and the rate of severe adverse health
events. The strength of the evidence means that we
cannot currently assume equivalence between the
two options.. Daily ICS was superior to intermittent
ICS in several indicators of lung function, airway
inflammation, asthma control and reliever use. Both
treatments appeared safe, but a modest growth
suppression was associated with daily, compared to
intermittent, inhaled budesonide and
beclomethasone. Clinicians should carefully weigh
the potential benefits and harm of each treatment
option, taking into account the unknown long-term (>
one year) impact of intermittent therapy on lung
growth and lung function decline.
Chaturvedi, S et al (2014) Pharmacological
interventions for hypertension in children.
Cochrane Database of Systematic Reviews (Online),
2, pp.CD008117. Link to Abstract Link to Full Text
Author’s Conclusions: Overall, there are
sparse data informing the use of antihypertensive
agents in children, with outcomes reported limited to
blood pressure and not end organ damage. The most
data are available for candesartan, for which there is
low-quality evidence of a modest lowering effect on
blood pressure. We did not find evidence of a
consistent dose response relationship for escalating
doses of angiotensin receptor blockers, calcium
channel blockers or angiotensin-converting enzyme
inhibitors. All agents appear safe, at least in the short
term.
Davey, P et al (2013) Interventions to improve
antibiotic prescribing practices for hospital
inpatients. Cochrane Database of Systematic
Reviews (Online), 4, pp.CD003543.
Link to Abstract Link to Full Text
Author’s Conclusions: The results show that
interventions to reduce excessive antibiotic
prescribing to hospital inpatients can reduce
antimicrobial resistance or hospital-acquired
infections, and interventions to increase effective
prescribing can improve clinical outcome. This
update provides more evidence about unintended
clinical consequences of interventions and about the
effect of interventions to reduce exposure of patients
to antibiotics. The meta-analysis supports the use of
restrictive interventions when the need is urgent, but
suggests that persuasive and restrictive interventions
are equally effective after six months.
Fernandes, RM et al (2013) Glucocorticoids for
acute viral bronchiolitis in infants and young
children. Cochrane Database of Systematic Reviews,
6, pp.CD004878. Link to Abstract Link to Full Text
Author’s Conclusions: Current evidence does not support a clinically relevant effect of systemic or inhaled glucocorticoids on admissions or length of hospitalisation. Combined dexamethasone and epinephrine may reduce outpatient admissions, but results are exploratory and safety data limited. Future research should further assess the efficacy, harms and applicability of combined therapy.
Flodgren, G et al (2013) Interventions to improve +
professional adherence to guidelines for
prevention of device-related infections. Cochrane
Database of Systematic Reviews (Online), 3,
pp.CD006559. Link to Abstract Link to Full Text
Author’s Conclusions: The low to very low quality of the evidence of studies included in this review provides insufficient evidence to determine with certainty which interventions are most effective in changing professional behaviour and in what contexts. However, interventions that may be worth further study are educational interventions involving more than one active element and that are repeatedly administered over time, and interventions employing specialised personnel, who are focused on an aspect of care that is supported by evidence e.g. dentists/dental auxiliaries performing oral care for VAP prevention.
Goldenberg, JZ et al (2013) Probiotics for the
prevention of Clostridium difficile-associated
diarrhoea in adults and children. Cochrane
Database of Systematic Reviews (Online), 5,
pp.CD006095. Link to Abstract Link to Full Text
Author’s Conclusions: Based on this systematic
review and meta-analysis of 23 randomized
controlled trials including 4213 patients, moderate
quality evidence suggests that probiotics are both
safe and effective for preventing Clostridium difficile-
associated diarrhoea.
Griffiths, B et al (2013) Combined inhaled
anticholinergics and short-acting beta2-agonists
for initial treatment of acute asthma in children.
Cochrane Database of Systematic Reviews (Online),
8, pp.CD000060. Link to Abstract Link to Full Text
Author’s Conclusions: Children with an asthma
exacerbation experience a lower risk of admission to
hospital if they are treated with the combination of
inhaled SABAs plus anticholinergic versus SABA
alone. They also experience a greater improvement
in lung function and less risk of nausea and tremor.
Within this group, the findings suggested, but did not
prove, the possibility of an effect modification, where
intensity of anticholinergic treatment and asthma
severity, could be associated with greater benefit.
Further research is required to identify the
characteristics of children that may benefit from
anticholinergic use (e.g. age and asthma severity
including mild exacerbation and impending
respiratory failure) and the treatment modalities
(dose, intensity, and duration) associated with most
benefit from anticholinergic use better.
Hemila, H et al (2013) Vitamin C for preventing and
treating the common cold. Cochrane Database of
Systematic Reviews (Online), 1, pp.CD000980.
Link to Abstract Link to Full Text
Author’s Conclusions: The failure of vitamin C
supplementation to reduce the incidence of colds in
the general population indicates that routine vitamin
C supplementation is not justified, yet vitamin C may
be useful for people exposed to brief periods of
severe physical exercise. Regular supplementation
trials have shown that vitamin C reduces the duration
of colds, but this was not replicated in the few
therapeutic trials that have been carried out.
Nevertheless, given the consistent effect of vitamin C
on the duration and severity of colds in the regular
supplementation studies, and the low cost and safety,
it may be worthwhile for common cold patients to test
on an individual basis whether therapeutic vitamin C
is beneficial for them. Further therapeutic RCTs are
warranted.
Hemila, H et al (2013) Vitamin C for preventing and
treating pneumonia. Cochrane Database of
Systematic Reviews (Online), 8, pp.CD005532.
Link to Abstract Link to Full Text
Author’s Conclusions: The prophylactic use of
vitamin C to prevent pneumonia should be further
investigated in populations who have a high
incidence of pneumonia, especially if dietary vitamin
C intake is low. Similarly, the therapeutic effects of
vitamin C should be studied, especially in patients
with low plasma vitamin C levels. The current
evidence is too weak to advocate prophylactic use of
vitamin C to prevent pneumonia in the general
population. Nevertheless, therapeutic vitamin C
supplementation may be reasonable for pneumonia
patients who have low vitamin C plasma levels
because its cost and risks are low.
Jain, K et al (2013) Bronchoscopy-guided
antimicrobial therapy for cystic fibrosis. Cochrane
database of systematic reviews (Online), 12,
pp.CD009530. Link to Abstract Link to Full Text
Author’s Conclusions: This review, which only
includes a single study, shows that there is no clear
evidence to support the routine use of
bronchoalveolar lavage for the diagnosis and
management of pulmonary infection in pre-school
children with cystic fibrosis compared to the standard
practice of providing treatment based on results of
oropharyngeal culture and clinical symptoms. No
evidence was available for adult and adolescent
populations.
Kew, KM et al (2013) Combination formoterol and
budesonide as maintenance and reliever therapy
versus combination inhaler maintenance for
chronic asthma in adults and children. Cochrane
Database of Systematic Reviews (Online), 12,
pp.CD009019. Link to Abstract Link to Full Text
Author’s Conclusions: SiT reduces the
number of people having asthma exacerbations
requiring oral steroids and the number requiring
hospitalisation or an ER visit compared with fixed-
dose combination inhalers. Evidence for serious
adverse events was unclear. The mean daily dose of
inhaled corticosteroids (ICS) in SiT, including the
total dose administered with reliever use, was always
lower than that of the other combination groups. This
suggests that the flexibility in steroid administration
that is possible with SiT might be more effective than
a standard fixed-dose combination by increasing the
dose only when needed and keeping it low during
stable stages of the disease. Data for hospitalisations
alone could not be obtained, and no studies have yet
addressed this question in children younger than age
12.
Lambert, P et al (2014) Clonidine premedication
for postoperative analgesia in children. Cochrane
database of systematic reviews (Online), 1,
pp.CD009633. Link to Abstract Link to Full Text
Author’s Conclusions: There were only 11 relevant
trials studying 742 children having surgery where
premedication with clonidine was compared to
placebo or other drug treatment. Despite
heterogeneity between trials, clonidine premedication
in an adequate dosage (4 microg/kg) was likely to
have a beneficial effect on postoperative pain in
children. Side effects were minimal, but some of the
studies used atropine prophylactically with the
intention of preventing bradycardia and hypotension.
Further research is required to determine under what
conditions clonidine premedication is most effective
in providing postoperative pain relief in children.
Macgillivray, S et al (2013) Lactose avoidance for
young children with acute diarrhoea. Cochrane
Database of Systematic Reviews (Online), 10,
pp.CD005433. Link to Abstract Link to Full Text
Author’s Conclusions: In young children with
acute diarrhoea who are not predominantly breast-
fed, change to a lactose-free diet may result in earlier
resolution of acute diarrhoea and reduce treatment
failure. Diluting lactose-containing formulas may also
have some benefits but further trials are required to
have confidence in this finding. There are no trials
from low-income countries, where mortality for
diarrhoea is high, and malnutrition is more common.
Minozzi, S et al (2013) Maintenance agonist
treatments for opiate-dependent pregnant women.
Cochrane Database of Systematic Reviews (Online),
12, pp.CD006318. Link to Abstract
Author’s Conclusions: We did not find sufficient
significant differences between methadone and
buprenorphine or slow-release morphineto allow
us to conclude that one treatment is superior to
another for all relevant outcomes. While methadone
seems superior in terms of retaining patients in
treatment, buprenorphine seems to lead to less
severe neonatal abstinence syndrome. Additionally,
even though a multi-centre, international trial with
175 pregnant women has recently been completed
and its results published and included in this review,
the body of evidence is still too small to draw firm
conclusions about the equivalence of the treatments
compared. There is still a need for randomised
controlled trials of adequate sample size comparing
different maintenance treatments.
Morrow, B et al (2013) Mechanical insufflation-
exsufflation for people with neuromuscular
disorders. Cochrane Database of Systematic
Reviews (Online), 12, pp.CD010044.
Link to Abstract Link to Full Text
Author’s Conclusions: The results of this
review do not provide sufficient evidence on which to
base clinical practice as we were unable to address
important short- and long-term outcomes, including
adverse effects of MI-E. There is currently insufficient
evidence for or against the use of MI-E in people with
NMDs. Further randomised controlled clinical trials
are needed to test the safety and efficacy of MI-E.
Mutter, TC et al (2013) Hydroxyethyl starch (HES)
versus other fluid therapies: effects on kidney
function. Cochrane Database of Systematic
Reviews (Online), 7, pp.CD007594. Link to Abstract
Author’s Conclusions: The current evidence suggests
that all HES products increase the risk in AKI and
RRT in all patient populations and a safe volume of
any HES solution has yet to be determined. In most
clinical situations it is likely that these risks outweigh
any benefits, and alternate volume replacement
therapies should be used in place of HES products.
Normansell, R et al (2014) Omalizumab for asthma
in adults and children. Cochrane Database of
Systematic Reviews (Online), 1, pp.CD003559.
Link to Abstract Link to Full Text
Author’s Conclusions: Omalizumab was effective in
reducing asthma exacerbations and hospitalisations
as an adjunctive therapy to inhaled steroids and
during steroid tapering phases of clinical trials.
Omalizumab was significantly more effective than
placebo in increasing the numbers of participants
who were able to reduce or withdraw their inhaled
steroids. Omalizumab was generally well tolerated,
although more injection site reactions were seen with
omalizumab. Further assessment in paediatric
populations is necessary, as is direct double-dummy
comparison with ICS. Although subgroup analyses
suggest that participants receiving prednisolone had
better asthma control when they received
omalizumab,it remains to be tested prospectively
whether the addition of omalizumab has a
prednisolone-sparing effect. It is also not clear
whether there is a threshold level of baseline serum
IgE for optimum efficacy of omalizumab. Given the
high cost of the drug, identification of biomarkers
predictive of response is of major importance for
future research.
Osborn, DA et al (2013) Prebiotics in infants for
prevention of allergy. Cochrane database of
systematic reviews (Online), 3, pp.CD006474.
Link to Abstract Link to Full Text
Author’s Conclusions: Further research is needed
before routine use of prebiotics can be recommended
for prevention of allergy in formula fed infants. There
is some evidence that a prebiotic supplement added
to infant feeds may prevent eczema. It is unclear
whether the use of prebiotic should be restricted to
infants at high risk of allergy or may have an effect in
low risk populations; or whether it may have an effect
on other allergic diseases including asthma.
Schoot, RA et al (2013) Systemic treatments for
the prevention of venous thrombo-embolic
events in paediatric cancer patients with
tunnelled central venous catheters. Cochrane
Database of Systematic Reviews (Online), 9,
pp.CD009160. Link to Abstract Link to Full Text
Author’s Conclusions: We found no significant effects
of systemic treatments compared with no intervention
in preventing (a)symptomatic VTE in paediatric
oncology patients with CVCs. However, this could be
a result of the low number of included participants,
which resulted in low power. In one CCT, which
compared one systemic treatment with another
systemic treatment, we identified a significant
reduction in symptomatic VTE with the addition of
LMWH to AT supplementation. All studies
investigated the prevalence of major and/or minor
bleeding episodes, and none found a significant
difference between study groups. None of the studies
reported thrombocytopenia, HIT, HITT, death as a
result of VTE, removal of CVC due to VTE, CVC-
related infection or PTS among participants. On the
basis of currently available evidence, we are not able
to give recommendations for clinical practise.
Additional well-designed international RCTs are
needed to further explore the effects of systemic
treatments in preventing VTE. Future studies should
aim for adequate power with attainable sample sizes.
The incidence of symptomatic VTE is relatively low;
therefore, it might be necessary to select participants
with thrombotic risk factors or to investigate
asymptomatic VTE instead.
Spinks, A et al (2013) Antibiotics for sore throat.
Cochrane Database of Systematic Reviews (Online),
11, pp.CD000023. Link to Abstract Link to Full Text
Author’s Conclusions Antibiotics confer relative
benefits in the treatment of sore throat. However, the
absolute benefits are modest. Protecting sore throat
sufferers against suppurative and non-suppurative
complications in high-income countries requires
treating many with antibiotics for one to benefit. This
NNTB may be lower in low-income countries.
Antibiotics shorten the duration of symptoms by
about 16 hours overall.
Thanaviratananich, S et al (2013) Once or twice
daily versus three times daily amoxicillin with or
without clavulanate for the treatment of acute
otitis media. Cochrane Database of Systematic
Reviews (Online), 12, pp.CD004975. Link to Abstract
Author’s Conclusions: This review showed that the
results of using once or twice daily doses of
amoxicillin, with or without clavulanate, were
comparable with three doses for the treatment of
AOM.
Ullman, AJ et al (2013) Optimal timing for
intravascular administration set replacement.
Cochrane database of systematic reviews (Online), 9,
pp.CD003588. Link to Abstract Link to Full Text
Author’s Conclusions: Some evidence indicates that
administration sets that do not contain lipids, blood or
blood products may be left in place for intervals of up
to 96 hours without increasing the risk of infection.
Other evidence suggests that mortality increased
within the neonatal population with infrequent
administration set replacement. However, much the
evidence obtained was derived from studies of low to
moderate quality.
Uman, LS et al (2013) Psychological interventions
for needle-related procedural pain and distress in
children and adolescents. Cochrane Database of
Systematic Reviews (Online), 10, pp.CD005179.
Link to Abstract Link to Full Text
Author’s Conclusions: Overall, there is strong
evidence supporting the efficacy of distraction and
hypnosis for needle-related pain and distress in
children and adolescents, with no evidence currently
available for preparation and information or both,
combined CBT, parent coaching plus distraction,
suggestion, or virtual reality. Additional research is
needed to further assess interventions that have only
been investigated in one RCT to date (that is,
memory alteration, parent positioning plus distraction,
blowing out air, and distraction plus suggestion).
There are continuing issues with the quality of trials
examining psychological interventions for needle-
related pain and distress.
van Driel, ML et al (2013) Different antibiotic
treatments for group A streptococcal pharyngitis.
Cochrane Database of Systematic Reviews (Online),
4, pp.CD004406. Link to Abstract Link to Full Text
Author’s Conclusions: Evidence is insufficient to
show clinically meaningful differences between
antibiotics for GABHS tonsillopharyngitis. Limited
evidence in adults suggests cephalosporins are more
effective than penicillin for relapse, but the NNTB is
high. Limited evidence in children suggests
carbacephem is more effective for symptom
resolution. Data on complications are too scarce to
draw conclusions. Based on these results and
considering the low cost and absence of resistance,
penicillin can still be recommended as first choice.
Venekamp, RP et al (2013) Antibiotics for acute
otitis media in children. Cochrane Database of
Systematic Reviews (Online), 1, pp.CD000219.
Link to Abstract Link to Full Text
Author’s Conclusions: Antibiotic treatment led to a
statistically significant reduction of children with AOM
experiencing pain at two to seven days compared
with placebo but since most children (82%) settle
spontaneously, about 20 children must be treated to
prevent one suffering from ear pain at two to seven
days. Additionally, antibiotic treatment led to a
statistically significant reduction of tympanic
membrane perforations (NNTB 33) and contralateral
AOM episodes (NNTB 11). These benefits must be
weighed against the possible harms: for every 14
children treated with antibiotics, one child
experienced an adverse event (such as vomiting,
diarrhoea or rash) that would not have occurred if
antibiotics had been withheld. Antibiotics appear to
be most useful in children under two years of age
with bilateral AOM, or with both AOM and otorrhoea.
For most other children with mild disease, an
expectant observational approach seems justified.
We have no trials in populations with higher risks of
complications.
Zhang, L et al (2013) Nebulised hypertonic saline
solution for acute bronchiolitis in infants.
Cochrane Database of Systematic Reviews (Online),
7, pp.CD006458. Link to Abstract Link to Full Text
Author’s Conclusions: Current evidence suggests
nebulised 3% saline may significantly reduce the
length of hospital stay among infants hospitalised
with non-severe acute viral bronchiolitis and improve
the clinical severity score in both outpatient and
inpatient populations.
NICE Guidelines
NICE (2013) Atopic eczema in children. London:
Nice. Quality Standard QS 44. Link to Full Text
Abstract: This quality standard covers the
management of atopic eczema in children from birth
up to the age of 12 years
NICE (2013) Autism: Management of Autism in
Children and Young People. London: NICE. Clinical
Guidance CG 170. Link to Full Text
Abstract: This clinical guideline offers evidence-
based advice on the care and management of
children and young people with autism.
NICE (2013) Depression in Children and Young
People. London: NICE. Quality Standard QS 48.
Abstract: This quality standard covers the diagnosis
and management of depression in children and
young people aged between 5 and 17 years (that is,
up to their 18th birthday).
NICE (2013) Feverish Illness in Children. London:
NICE. Clinical Guidance CG 160). Link to Full Text
This clinical guideline updates and replaces NICE clinical guideline 47 (published May 2007). It offers evidence-based advice on the care of young children with feverish illness.
New and updated recommendations have been included in areas relating to assessment and initial management in children younger than 5 years with no obvious cause of feverish illness
NICE (2013) Headaches in Young People and
Adults. London: NICE. Quality Standard QS 42.
Abstract: This quality standard covers the diagnosis and management of the most common primary headache disorders (tension-type headache, migraine and cluster headache) and medication overuse headache in adults and young people aged 12 years and older
NICE (2014) Head injury: Triage, assessment, investigation and early management of head injury in children, young people and adults. London, NICE. CG 176 Link to Full Text
Abstract: This guidance partially updates and replaces NICE clinical guideline CG56. It offers evidence-based advice on the care of children, young people and adults with head injury.
NICE (2013) Managing overweight and obesity among children and young people: lifestyle weight management services. NICE. Public Health PH 47 Link to Full Text
Abstract: This guidance makes recommendations on lifestyle weight management (sometimes called tier 2) services for overweight and obese children and young people aged under 18. These services are just one part of a comprehensive approach to preventing and treating obesity.
NICE (2013) Urinary Tract Infection in Infants,
Children and Young People Under 16. London:
NICE. Quality standard QS 36 Link to Full Text
Abstract: This quality standard covers the care of infants, children and young people under 16 years with a first or recurrent upper or lower urinary tract infection and without known underlying uropathy
Reports & Statistics
Oliva, L et al 2013 Overlooked and forgotten: a
review of how well children and young people's
mental health is being prioritised in the current
commissioning landscape. CaYPsMH
London: CYPMHC. Link to Full Text
Abstract: This report offers support and
recommendations to health and wellbeing boards on
how they can prioritise and address children and
young people’s mental health. It is based on a review
of 145 joint strategic needs assessment (JSNAs) and
142 joint health and wellbeing strategies (JHWSs)
General
Adams, S et al (2013) Exploring the usefulness of
comprehensive care plans for children with
medical complexity (CMC): a qualitative study.
BMC Pediatrics, 13, pp.10. Link to Abstract
Boutis, K et al (2013) Effect of the Low Risk Ankle
Rule on the frequency of radiography in children
with ankle injuries. CMAJ : Canadian Medical
Association Journal = Journal de l'Association
Medicale Canadienne, 185 (15), pp.E731-738.
Doi: 10.1503/cmaj.122050. Link to Abstract
Brown, CC et al (2014) Making your way as an
academic paediatric trainee in the UK. Archives of
Disease in Childhood - Education & Practice Edition,
99 (1), pp.13-14. Link to Abstract Link to Full Text
Eisen, S et al (2014) Peer mentoring: evaluation of
a novel programme in paediatrics. Archives of
Disease in Childhood, 99 (2), pp.142-146.
Link to Abstract Link to Full Text
Eventov-Friedman, S et al (2014) Using a safe taxi
service to transport newborn babies home from
hospital. Acta Paediatrica, 103 (1), pp.57-61.
Ferro, MA (2014) Adolescents and young adults
with physical illness: a comparative study of
psychological distress. Acta Paediatrica, 103 (1),
pp.e32-e37. Link to Abstract
Gaab, EM et al (2014) Siblings Caring for and
about Pediatric Palliative Care Patients. Journal of
Palliative Medicine, 17 (1), pp.62-67. Link to Abstract
Goddard, JM (2014) Chronic pain in Children and
Young People. Paediatrics and Child Health, 24 (2),
pp.89-91. Link to Abstract
Hall, AE et al (2014) What ethical and legal
principles should guide the genotyping of
children as part of a personalised screening
programme for common cancer? Journal of
Medical Ethics, 40 (3), pp.163-167. Link to Abstract
Kamble, S et al (2014) The acceptability among
young Hindus and Muslims of actively ending the
lives of newborns with genetic defects. Journal of
Medical Ethics, 40 (3), pp.186-191. Link to Abstract
Klaber, RE et al (2014) Delivering quality
improvement: the need to believe it is necessary.
Archives of Disease in Childhood, 99 (2), pp.175-179.
Link to Abstract Link to Full Text
Myors, KA et al (2014) Child and family health
nurses working with families of preschool-aged
children. Journal of Clinical Nursing, 23 (1-2),
pp.181-190. Link to Abstract Link to Full Text
O'Donnell, HC et al (2014) Impact of Newborn
Follow-up Visit Timing on Subsequent ED Visits
and Hospital Readmissions: An Instrumental
Variable Analysis. Academic Pediatrics, 14 (1),
pp.84-91. Link to Abstract
O'Donnell, HC et al (2014) Factors Associated With
Timing of First Outpatient Visit After Newborn
Hospital Discharge. Academic Pediatrics, 14 (1),
pp.77-83. Link to Abstract
Pitchforth, J et al (2014) Improving the use of
phlebotomy services in a paediatric inpatient
setting. BMJ Quality Improvement Reports, 2 (2)
Sahib El-Radhi, A (2014) Determining fever in
children: the search for an ideal thermometer.
British Journal of Nursing (Mark Allen Publishing), 23
(2), pp.91-94. Link to Abstract
Simon, TD et al (2013) Quality Improvement
Research in Pediatric Hospital Medicine and the
Role of the Pediatric Research in Inpatient
Settings (PRIS) Network. Academic Pediatrics, 13
(6, Supplement), pp.S54-S60. Link to Abstract
Slopen, N et al (2014) Cumulative Adversity in
Childhood and Emergent Risk Factors for Long-
Term Health. The Journal of Pediatrics, 164 (3),
pp.631-638.e632. Link to Abstract
Soares, NS et al (2014) The Influence of
Community Access to Child Health (CATCH)
Program on Community Pediatrics. Pediatrics, 133
(1), pp.e205-e212. Link to Abstract
Vanhelst, J et al (2013) Effect of child health status
on parents' allowing children to participate in
pediatric research. BMC Medical Ethics, 14, pp.7.
Link to Abstract Link to Full Text
Wekell, P et al (2014) Devising a competency-
based continuing professional development
programme to meet the needs of on-call
consultant paediatricians. Acta Paediatrica, 103 (3),
pp.320-330. Link to Abstract
Zhang, LF et al (2014) A systematic review of the
psychometric properties of transition readiness
assessment tools in adolescents with chronic
disease. BMC Pediatrics, 14 (1), pp.4.
Link to Abstract Link to Full Text
Allergy
Anagnostou, K et al (2014) Assessing the efficacy
of oral immunotherapy for the desensitisation of
peanut allergy in children (STOP II): a phase 2
randomised controlled trial. Lancet, Online first
30th January 2014 Link to Abstract Link to Full Text
Francavilla, R et al (2014) Clinical, Serologic, and
Histologic Features of Gluten Sensitivity in
Children. The Journal of Pediatrics, 164 (3), pp.463-
467.e461. Link to Abstract
Grimshaw, KE et al (2013) Diet and food allergy
development during infancy: Birth cohort study
findings using prospective food diary data. The
Journal of Allergy and Clinical Immunology, 133 (2),
pp 511-519 Link to Abstract
Gupta, R et al (2013) The economic impact of
childhood food allergy in the United States. JAMA
Pediatrics, 167 (11), pp.1026-1031. Link to Abstract
Indinnimeo, L et al (2013) Duration of a cow-milk
exclusion diet worsens parents' perception of
quality of life in children with food allergies. BMC
Pediatrics, 13, pp.203. Link to Abstract
Jackson, J et al (2013) Cognitive and psychosocial
function post hematopoietic stem cell
transplantation in children with hemophagocytic
lymphohistiocytosis. The Journal of Allergy and
Clinical Immunology, 132 (4), pp.889-895 e881-883.
Just, J et al (2014) Childhood Allergic Asthma Is
Not a Single Phenotype. The Journal of Pediatrics,
Published on line ahead of print. Link to Abstract
Pfaar, O et al (2013) Depigmented-polymerized
mixed grass/birch pollen extract immunotherapy
is effective in polysensitized patients. Allergy, 68
(10), pp.1306-1313. Link to Abstract
Anaesthetics and Analgesia
Bredlau, AL et al (2013) Ketamine for Pain in
Adults and Children with Cancer: A Systematic
Review and Synthesis of the Literature. Pain
Medicine (Malden, Mass.), Published ahead of print
Herpertz-Dahlmann, B et al (2014) Day-patient
treatment after short inpatient care versus
continued inpatient treatment in adolescents with
anorexia nervosa (ANDI): a multicentre,
randomised, open-label, non-inferiority trial.
Lancet, Link to Abstract
Naja, ZM et al (2013) The effectiveness of
pudendal nerve block versus caudal block
anesthesia for hypospadias in children.
Anesthesia and Analgesia, 117 (6), pp.1401-1407.
Bone and Joint
McDevitt, H et al (2014) Establishing good bone
health in children. Paediatrics and Child Health, 24
(2), pp.78-82. Link to Abstract
Shrestha, D et al (2013) Systemic lupus
erythematosus and granulomatous
lymphadenopathy. BMC Pediatrics, 13, pp.179.
Link to Abstract Link to Full Text
Son, MBF et al (2014) Outcomes in Hospitalized
Pediatric Patients With Systemic Lupus
Erythematosus. Pediatrics, 133 (1), pp.e106-e113.
Cardiovascular
Aiyagari, R et al (2013) Impact of pre-stage II
hemodynamics and pulmonary artery anatomy on
12-month outcomes in the Pediatric Heart
Network Single Ventricle Reconstruction trial.
The Journal of Thoracic and Cardiovascular Surgery,
Published on line 13th December 2013
Bijlsma, MW et al (2014) Why Pediatricians Fail to
Diagnose Hypertension: A Multicenter Survey.
The Journal of Pediatrics, 164 (1), pp.173-177.e177.
Cabrera-Rego, JO et al (2014) Epicardial Fat
Thickness Correlates With Carotid Intima-Media
Thickness, Arterial Stiffness, and Cardiac
Geometry in Children and Adolescents. Pediatric
Cardiology, 35 (30), pp. 450-460 Link to Abstract
Carli, D et al (2014) VACTERL (Vertebral Defects,
Anal Atresia, Tracheoesophageal Fistula
with Esophageal Atresia, Cardiac Defects, Renal
and Limb Anomalies) Association: Disease
Spectrum in 25 Patients Ascertained for Their
Upper Limb Involvement. The Journal of Pediatrics,
164 (3), pp.458-462.e452. Link to Abstract
Dilli, D et al (2013) Treatment outcomes of infants
with cyanotic congenital heart disease treated
with synbiotics. Pediatrics, 132 (4), pp.e932-938.
Eleftheriou, D et al (2014) Vasculitis in children. 24
(2), pp.58-63. Link to Abstract
Mellion, K et al (2014) Health-Related Quality of
Life Outcomes in Children and Adolescents with
Congenital Heart Disease. The Journal of Pediatrics,
Published online 13th January 2014.
Mullett, MD et al (2014) Association between Birth
Characteristics and Coronary Disease Risk
Factors among Fifth Graders. The Journal of
Pediatrics, 164 (1), pp.78-82. Link to Abstract
Oster, ME et al (2014) Quality Improvement in
Screening for Critical Congenital Heart Disease.
The Journal of Pediatrics, 164 (1), pp.67-71.e62.
Pretty, C et al (2013) Adverse childhood
experiences and the cardiovascular health of
children: a cross-sectional study. BMC Pediatrics,
13, pp.208. Link to Abstract Link to Full Text
Raj, S et al (2014) Myocardial Dysfunction in
Pediatric Septic Shock. The Journal of Pediatrics,
164 (1), pp.72-77.e72 Link to Abstract
Studer, MA et al (2014) Newborn Pulse Oximetry
Screening to Detect Critical Congenital Heart
Disease. The Journal of Pediatrics, 164 (3), pp.505-
509.e502. Link to Abstract
Takemoto, CM et al (2014) Hospital-Associated
Venous Thromboembolism in Children: Incidence
and Clinical Characteristics. The Journal of
Pediatrics, 164 (2), pp.332-338. Link to Abstract
Uysal, F et al (2013) Congenital Anomalies of
Coronary Arteries in Children: The Evaluation of
22 Patients. Pediatric Cardiology, Published on line
12th December 2013. Link to Abstract
Werner, H et al (2014) Health-Related Quality of
Life after Open-Heart Surgery. The Journal of
Pediatrics, 164 (2), pp.254-258.e251. Link to Abstract
Williams, DM et al (2013) Associations of maternal
25-hydroxyvitamin D in pregnancy with offspring
cardiovascular risk factors in childhood and
adolescence: findings from the Avon
Longitudinal Study of Parents and Children. Heart
(British Cardiac Society), 99 (24), pp.1849-1856.
Link to Abstract Link to Full Text
Child Development
Bleakley, A et al (2014) Violent Film Characters’
Portrayal of Alcohol, Sex, and Tobacco-Related
Behaviors. Pediatrics, 133 (1), pp.71-77.
Link to Abstract Link to Full Text
Foli, KJ et al (2014) "Great expectations" of
adoptive parents: theory extension through
structural equation modeling. Nursing Research,
63 (1), pp.14-25. Link to Abstract
Ghassabian, A et al (2014) Early lexical
development and risk of verbal and nonverbal
cognitive delay at school age. Acta Paediatrica,
103 (1), pp.70-80. Link to Abstract
Hedenbro, M et al (2014) Early interaction between
infants and their parents predicts social
competence at the age of four. Acta Paediatrica,
103 (3), pp.268-274. Link to Abstract
Lee, HS et al (2013) The impact of the use of
antiepileptic drugs on the growth of children.
BMC Pediatrics, 13, pp.211. Link to Abstract
Luby, J et al (2013) The effects of poverty on
childhood brain development: the mediating
effect of caregiving and stressful life events.
JAMA Pediatrics, 167 (12), pp.1135-1142.
Sim, F et al (2013) Language and social/
emotionalproblems identified at a universal
developmental assessment at 30 months. BMC
Pediatrics, 13, pp.206. Link to Abstract
Vohr, BR et al (2014) The importance of language
in the home for school-age children with
permanent hearing loss. Acta Paediatrica, 103 (1),
pp.62-69. Link to Abstract Link to Full Text
Wong, SC et al (2014) The Prevalence of Turner
Syndrome in Girls Presenting with Coarctation of
the Aorta. The Journal of Pediatrics, 164 (2), pp.259-
263. Link to Abstract
Child Protection
Bailhache, M et al (2013) Is early detection of
abused children possible?: a systematic review
of the diagnostic accuracy of the identification
of abused children. BMC Pediatrics, 13, pp.202.
Doi: 10.1186/1471-2431-13-202. Link to Abstract
Foa, EB et al (2013) Prolonged exposure vs
supportive counseling for sexual abuse-related
PTSD in adolescent girls: a randomized clinical
trial. JAMA: the Journal of the American Medical
Association, 310 (24), pp.2650-2657.
Robertson, BD et al (2014) At-Risk Children of At-
Risk Parents: Assessing Common Injuries to
the Children of Teenage Parents. The Journal of
Pediatrics, 164 (2), pp.347-351.e341.
Ybarra, ML et al (2013) Prevalence rates of male
and female sexual violence perpetrators in a
national sample of adolescents. JAMA Pediatrics,
167 (12), pp.1125-1134. Links to Abstract
Emergency & High Dependency
Bohman, K et al (2014) Long-term medical
consequences for child occupants 0 to 12 years
injured in car crashes. Traffic Injury Prevention, 15
(4), pp.370-378. Link to Abstract
Cunningham, RM et al (2014) Characteristics of
Youth Seeking Emergency Care for Assault
Injuries. Pediatrics, 133 (1), pp.e96-e105.
Fedewa, MV et al (2014) Exercise and Insulin
Resistance in Youth: A Meta-Analysis. Pediatrics,
133 (1), pp.e163-e174. Link to Abstract
Hartling, L et al (2013) Music to reduce pain and
distress in the pediatric emergency department: a
randomized clinical trial. JAMA Pediatrics, 167 (9),
pp.826-835. Link to Abstract
Karbuz, A et al (2014) The Use of Colistin in
Critically Ill Children in a Pediatric Intensive Care
Unit. The Pediatric Infectious Disease Journal, 33 (1),
pp.e19-e24 Link to Abstract
Macias, CG (2013) Quality Improvement in
Pediatric Emergency Medicine. Academic
Pediatrics, 13 (6, Supplement), pp.S61-S68.
Macrae, D et al (2014) A randomized trial of
hyperglycemic control in pediatric intensive care.
The New England Journal of Medicine, 370 (2),
pp.107-118. Link to Abstract
Martino, F et al (2013) Hypertension in children
and adolescents attending a lipid clinic. European
Journal of Pediatrics, 172 (12), pp.1573-1579.
O’Neil, J et al (2014) Ambulance Transport of
Noncritical Children: Emergency Medical Service
Providers’ Knowledge, Opinions, and Practice.
Clinical Pediatrics, 53 (3), pp.250-255.
Roussak, P (2014) Centralisation of paediatric
intensive care and a 24-hour retrieval service.
British Journal of Nursing (Mark Allen Publishing), 23
(1), pp.25-29. Link to Abstract
Sacco Casamassima, M et al (2014) Use of risk
stratification indices to predict mortality in
critically ill children. European Journal Pediatrics,
173 (1), pp.1-13. Link to Abstract
Saxby, C et al (2014) Managing human factors in
the assembly of the paediatric bronchoscope.
BMJ Quality Improvement Reports, 2 (2)
Stickney, CA et al (2014) Family Participation
during Intensive Care Unit Rounds: Attitudes and
Experiences of Parents and Healthcare Providers
in a Tertiary Pediatric Intensive Care Unit. The
Journal of Pediatrics, 164 (2), pp.402-406.e404.
Sznajder, M et al (2013) Depressive symptoms
among teenagers in the emergency department:
prevalence estimate and concordance with
parental perceptions. European Journal Pediatrics,
172 (12), pp.1587-1596. Link to Abstract
Wang, GS et al (2014) Unintentional Pediatric
Exposures to Central Alpha-2 Agonists Reported
to the National Poison Data System. The Journal
of Pediatrics, 164 (1), pp.149-152. Link to Abstract
Wang, J et al (2014) Isotonic Versus Hypotonic
Maintenance IV Fluids in Hospitalized Children: A
Meta-Analysis. Pediatrics, 133 (1), pp.105-113.
Westergren, H et al (2014) First evaluation of the
paediatric version of the Swedish rapid
emergency triage and treatment system shows
good reliability. Acta Paediatrica, 103 (3), pp.305-
308. Link to Abstract
Endocrine & Diabetes
Aversa, T et al (2013) In young patients with
Turner or Down syndrome Graves' disease
presentation is often preceded by Hashimoto's
thyroiditis. Thyroid: Official Journal of the American
Thyroid Association, Published on line 29th January.
Cho, YH et al (2014) Puberty as an accelerator for
diabetes complications. Pediatric Diabetes, 15 (1),
pp.18-26. Link to Abstract
Fedewa, MV et al (2014) Exercise and insulin
resistance in youth: a meta-analysis. Pediatrics,
133 (1), pp.e163-174. Link to Abstract
Lyons, SK et al (2014) Transfer from pediatric to
adult health care: effects on diabetes outcomes.
Pediatric Diabetes, 15 (1), pp.10-17. Link to Abstract
Manios, Y et al (2014) Female sex, small size at
birth and low family income increase the
likelihood of insulin resistance in late childhood:
the Healthy Growth Study. Pediatric Diabetes, 15
(1), pp.41-50. Link to Abstract
Moreno-Castilla, C et al (2013) Low-carbohydrate
diet for the treatment of gestational diabetes
mellitus: a randomized controlled trial. Diabetes
Care, 36 (8), pp.2233-2238. Link to Abstract
Ng, SM et al (2014) Review of insulin treatment in
stress-related hyperglycaemia in children without
preexisting diabetes. Acta Paediatrica, 103 (1),
pp.6-9. Link to Abstract
Olausson, EA et al (2014) A Small Particle Size
Diet Reduces Upper Gastrointestinal Symptoms
in Patients With Diabetic Gastroparesis: A
Randomized Controlled Trial. The American
Journal of Gastroenterology, Published on line 14th
January. Link to Abstract
Pugliese, A et al (2014) The Juvenile Diabetes
Research Foundation Network for Pancreatic
Organ Donors with Diabetes (nPOD) Program:
goals, operational model and emerging findings.
Pediatric Diabetes, 15 (1), pp.1-9. Link to Full Text
Rosenbaum, M et al (2013) Racial/ethnic
differences in clinical and biochemical type 2
diabetes mellitus risk factors in children. Obesity
(Silver Spring, Md.), 21 (10), pp.2081-2090.
Sundberg, F et al (2014) Detection and treatment
efficacy of hypoglycemic events in the everyday
life of children younger than 7 yr. Pediatric
Diabetes, 15 (1), pp.34-40. Link to Abstract
Ear, Nose and Throat
Ahn, JH et al (2013) Outcomes of cochlear
implantation in children with CHARGE syndrome.
Acta oto-laryngologica, 133 (11), pp.1148-1153.
Benoit, MM et al (2013) The presentation and
management of mandibular tumors in the
pediatric population. The Laryngoscope, 123 (8),
pp.2035-2042. Link to Abstract
Bush, ML et al (2014) Delays in Diagnosis of
Congenital Hearing Loss in Rural Children. The
Journal of Pediatrics, 164 (2), pp.393-397.
Chang, R-KR et al (2014) Genetic Variants for
Long QT Syndrome among Infants and Children
from a Statewide Newborn Hearing Screening
Program Cohort. The Journal of Pediatrics, 164 (3),
pp.590-595.e593. Link to Abstract
Hopper, SM et al (2013) Topical Lidocaine to
Improve Oral Intake in Children With Painful
Infectious Mouth Ulcers: A Blinded, Randomized,
Placebo-Controlled Trial. Annals of Emergency
Medicine, 63 (3), pp. 292-299. Link to Abstract
Klingenberg, C et al (2014) Patient comfort during
treatment with heated humidified high flow nasal
cannulae versus nasal continuous positive
airway pressure: a randomised cross-over trial.
Archives of Disease in Childhood - Fetal and
Neonatal Edition, 99 (2), pp.F134-F137.
Link to Abstract Link to Full Text
Kutz, JW, Jr. et al (2013) Ciprofloxacin 0.3% +
dexamethasone 0.1% for the treatment for otitis
media. Expert Opinion on Pharmacotherapy, 14 (17),
pp.2399-2405. Link to Abstract
Lang, M et al (2013) A Systematic Review and
Meta-analysis of Endoscopic Balloon Dilation of
Pediatric Subglottic Stenosis. Otolaryngology –
head and neck surgery: official journal of American
Academy of Otolaryngology-Head and Neck
Surgery,150 (2), pp. 174-179 Link to Abstract
Lourenco, CB et al (2013) Child, neglect and oral
health. BMC Pediatrics, 13, pp.188. Link to Abstract
Marom, T et al (2014) Trends in otitis media-
related health care use in the United States, 2001-
2011. JAMA Pediatrics, 168 (1), pp.68-75.
Morimoto, N et al (2013) Gorham-Stout syndrome
affecting the temporal bone with cerebrospinal
fluid leakage. International Journal of Pediatric
Otorhinolaryngology, 77 (9), pp.1596-1600.
Shaikh, N et al (2014) Predicting Response to
Antimicrobial Therapy in Children with Acute
Sinusitis. The Journal of Pediatrics, 164 (3), pp.536-
541. Link to Abstract
Gastroenterology
Agha, BS et al (2013) Rare-earth magnet
ingestion: a childhood danger reaches
adolescence. Pediatric Emergency Care
29 (10), pp.1116-1118. Link to Abstract
Anabrees, J et al (2013) Probiotics for infantile
colic: a systematic review. BMC Pediatrics, 13,
pp.186. Link to Abstract Link to Full Text
Freedman, SB et al (2014) Pediatric Abdominal
Radiograph Use, Constipation, and Significant
Misdiagnoses. The Journal of Pediatrics, 164 (1),
pp.83-88.e82. Link to Abstract
Jericho, H et al (2014) Nausea Predicts Delayed
Gastric Emptying in Children. The Journal of
Pediatrics, 164 (1), pp.89-92. Link to Abstract
Lazzerini, M et al (2013) Effect of thalidomide on
clinical remission in children and adolescents
with refractory Crohn disease: a randomized
clinical trial. JAMA : the Journal of the American
Medical Association, 310 (20), pp.2164-2173.
Mercer, DF et al (2014) Serial Transverse
Enteroplasty Allows Children with Short Bowel to
Wean from Parenteral Nutrition. The Journal of
Pediatrics, 164 (1), pp.93-98. Link to Abstract
Naji, H et al (2013) Use of Surgisis for Abdominal
Wall Reconstruction in Children with Abdominal
Wall Defects. European Journal of Pediatric
Surgery: Official Journal of Austrian Association of
Pediatric Surgery, 24 (1), pp. 94-96. Link to Abstract
Ohsawa, I et al (2013) Leukocytosis and high
hematocrit levels during abdominal attacks of
hereditary angioedema. BMC Gastroenterology, 13,
pp.123. Link to Abstract Link to Full Text
Rosen, R (2014) Gastroesophageal Reflux in
Infants: More Than Just a pHenomenon. JAMA
Pediatrics, 168 (1), pp.83-89. Link to Abstract
Sarker, SA et al (2013) Anti-rotavirus protein
reduces stool output in infants with diarrhea: a
randomized placebo-controlled trial.
Gastroenterology, 145 (4), pp.740-748 e748.
Saucier, A et al (2014) Prospective Evaluation of a
Clinical Pathway for Suspected Appendicitis.
Pediatrics, 133 (1), pp.e88-e95. Link to Abstract
Sung, V et al (2013) Probiotics to Prevent or Treat
Excessive Infant Crying: Systematic Review and
Meta-analysis. JAMA Pediatrics, 167 (12), pp.1150-
1157. Link to Abstract.
Szajewska, H et al (2014) Meta-analysis shows
limited evidence for using Lactobacillus
acidophilus LB to treat acute gastroenteritis in
children. Acta Paediatrica, 103 (3), pp.249-255.
Tappin, D et al (2013) Development of an early
nurse led intervention to treat children referred to
secondary paediatric care with constipation with
or without soiling. BMC Pediatrics, 13, pp.193.
Link to Abstract Link to Full Text
Toporowska-Kowalska, E et al (2013) Diagnosis of
gastroesophageal reflux and anti-reflux
procedures among Polish children with
gastrostomies: a 10-year nationwide analysis.
European Journal of Clinical Nutrition, 67 (11),
pp.1169-1174. Link to Abstract Link to Full Text
Tsiountsioura, M et al (2014) Detailed assessment
of nutritional status and eating patterns in
children with gastrointestinal diseases attending
an outpatients clinic and contemporary healthy
controls. European Journal of Clinical Nutrition,
Published online 15th January. Link to Abstract
Wang, L et al (2013) Selective endoscopic ligation
for treatment of upper gastrointestinal
protuberant lesions. World Journal of
Gastroenterology: WJG, 19 (33), pp.5581-5585.
Link to Abstract Link to Full Text
Waugh, N et al (2013) Faecal calprotectin testing
for differentiating amongst inflammatory and
non-inflammatory bowel diseases: systematic
review and economic evaluation. Health
Technology Assessment (Winchester, England), 17
(55), pp.xv-xix, 1-211. Link to Abstract
Whyte, LA et al (2014) Coeliac disease is more
common in children with high socio-economic
status. Acta Paediatrica, 103 (3), pp.289-294.
Wu, F-Y et al (2013) Long-term Outcome After
Percutaneous Endoscopic Gastrostomy in
Children. Pediatrics & Neonatology, 54 (5), pp.326-
329. Link to Abstract
Haematology
Ezenwosu, OU et al (2013) Determinants of
academic performance in children with sickle cell
anaemia. BMC Pediatrics, 13, pp.189.
Link to Abstract Link to Full Text
Fraser, C et al (2013) Open-label Bendamustine
Monotherapy for Pediatric Patients With
Relapsed or Refractory Acute Leukemia: Efficacy
and Tolerability. Journal of Pediatric Hematology/
Oncology, Published on line31st October 2013
Goldman, RD et al (2013) Intravenous magnesium
sulfate for vaso-occlusive episodes in sickle cell
disease. Pediatrics, 132 (6), pp.e1634-1641.
Jackson, J et al (2013) Cognitive and psychosocial
function post hematopoietic stem cell
transplantation in children with hemophagocytic
lymphohistiocytosis. The Journal of Allergy and
Clinical Immunology, 132 (4), pp.889-895 e881-883.
Lagunju, IA et al (2013) Chronic blood transfusion
for primary and secondary stroke prevention in
Nigerian children with sickle cell disease: a 5-
year appraisal. Pediatric Blood & Cancer, 60 (12),
pp.1940-1945. Link to Abstract
Ridefelt, P et al (2014) Estimating reliable
paediatric reference intervals in clinical
chemistry and haematology. Acta Paediatrica, 103
(1), pp.10-15. Link to Abstract
Sazawal, S et al (2014) Efficiency of red cell
distribution width in identification of children
aged 1-3 years with iron deficiency anemia
against traditional hematological markers. BMC
Pediatrics, 14 (1), pp.8. Link to Abstract
Uijterschout, L et al (2013) Prevalence and Risk
Factors of Iron Deficiency in Healthy Young
Children in the Southwestern Region of the
Netherlands. Journal of Pediatric Gastroenterology
and Nutrition, 58 (2), pp. 195-200. Link to Abstract
Vitagliano, O et al (2013) The Bcl-2/Bax and
Ras/Raf/MEK/ERK signaling pathways:
implications in pediatric leukemia pathogenesis
and new prospects for therapeutic approaches.
Expert Review of Hematology, 6 (5), pp.587-597.
Immunology & Immunisation
Albright, K et al (2014) Provider Attitudes Toward
Public-Private Collaboration to Improve
Immunization Reminder/Recall: A Mixed-Methods
Study. Academic Pediatrics, 14 (1), pp.62-70.
Arnheim-Dahlstrom, L et al (2013) Autoimmune,
neurological, and venous thromboembolic
adverse events after immunisation of adolescent
girls with quadrivalent human papillomavirus
vaccine in Denmark and Sweden: cohort study.
BMJ (Clinical research ed.), 347, pp.f5906.
Link to Abstract Link to Full Text
Glanz, JM et al (2013) Association between
undervaccination with diphtheria, tetanus toxoids,
and acellular pertussis (DTaP) vaccine and risk of
pertussis infection in children 3 to 36 months of
age. JAMA Pediatrics, 167 (11), pp.1060-1064.
Halperin, SA et al (2014) Safety and
Immunogenicity of a Toddler Dose Following an
Infant Series of a Hexavalent Diphtheria, Tetanus,
Acellular Pertussis, Inactivated Poliovirus,
Haemophilus influenzae Type b, Hepatitis B
Vaccine Administered Concurrently or at
Separate Visits With a Heptavalent
Pneumococcal Conjugate Vaccine. The Pediatric
Infectious Disease Journal, 33 (1), pp.73-80
Hollm-Delgado, M-G et al (2014) Acute Lower
Respiratory Infection Among Bacille Calmette-
Guérin (BCG)–Vaccinated Children. Pediatrics,
133 (1), pp.e73-e81. Link to Abstract
Holman, DM et al (2014) Barriers to Human
Papillomavirus Vaccination Among US
Adolescents: A Systematic Review of the
Literature. JAMA Pediatrics, 168 (1), pp.76-82.
Jain, VK et al (2013) Vaccine for prevention of mild
and moderate-to-severe influenza in children. The
New England Journal of Medicine, 369 (26), pp.2481-
2491. Link to Abstract
Lee, P-I et al (2013) Recommendations for
Rotavirus Vaccine. Pediatrics & Neonatology, 54 (6),
pp.355-359. Link to Abstract
Opel, DJ et al (2013) The relationship between
parent attitudes about childhood vaccines survey
scores and future child immunization status: a
validation study. JAMA Pediatrics, 167 (11),
pp.1065-1071. Link to Abstract
Prymula, R et al (2014) Protection against varicella
with two doses of combined measles-mumps-
rubella-varicella vaccine versus one dose of
monovalent varicella vaccine: a multicentre,
observer-blind, randomised, controlled trial.
Lancet, Published online 29th January
Rowhani-Rahbar, A et al (2013) Effect of age on the
risk of Fever and seizures following immunization
with measles-containing vaccines in children.
JAMA Pediatrics, 167 (12), pp.1111-1117.
Tom, JO et al (2014) Personal Health Record Use
and Association with Immunizations and Well-
Child Care Visits Recommendations. The Journal
of Pediatrics, 164 (1), pp.112-117. Link to Abstract
Infant Feeding
Badiee, Z et al (2013) The Calming Effect of
Maternal Breast Milk Odor on Premature Infants.
Pediatrics & Neonatology, 54 (5), pp.322-325.
Bevan, G et al (2014) Interventions in exclusive
breastfeeding: a systematic review. British Journal
of Nursing (Mark Allen Publishing), 23 (2), pp.86-89.
Bonuck, K et al (2014) Bottle-Weaning Intervention
and Toddler Overweight. The Journal of Pediatrics,
164 (2), pp.306-312.e302. Link to Abstract
Brown, A et al (2013) Breastfeeding is associated
with a maternal feeding style low in control from
birth. PloS One, 8 (1), pp.e54229. Link to Abstract
Chang, J-C et al (2013) Influence of Prolonged
Storage Process, Pasteurization, and Heat
Treatment on Biologically-active Human Milk
Proteins. Pediatrics & Neonatology, 54 (6), pp.360-
366. Link to Abstract
Emond, A et al (2013) Randomised controlled trial
of early frenotomy in breastfed infants with mild-
moderate tongue-tie. Archives of Disease in
Childhood. Fetal and Neonatal Edition, Published
online 18th November. Link to Full Text
Gaffney, KF et al (2014) Postpartum Depression,
Infant Feeding Practices, and Infant Weight Gain
at Six Months of Age. Journal of Pediatric Health
Care: Official Publication of National Association of
Pediatric Nurse Associates & Practitioners, 28 (1),
pp.43-50. Link to Abstract
Gibbs, BG et al (2014) Breastfeeding, Parenting,
and Early Cognitive Development. The Journal of
Pediatrics, 164 (3), pp.487-493. Link to Abstract
Hawkins, SS et al (2014) Compliance with the
Baby-Friendly Hospital Initiative and impact on
breastfeeding rates. Archives of Disease in
Childhood - Fetal and Neonatal Edition, 99 (2),
pp.F138-F143. Link to Abstract Link to Full Text
Hill, GD et al (2014) Feeding Dysfunction in
Children with Single Ventricle Following Staged
Palliation. The Journal of Pediatrics, 164 (2),
pp.243-246.e241. Link to Abstract
Howe, LD et al (2013) Trajectories of
socioeconomic inequalities in health, behaviours
and academic achievement across childhood and
adolescence. Journal of Epidemiology and
community health, 67 (4), pp. 358-364
Link to Abstract Link to Full Text
Hwang, Y-S et al (2013) Associations Among
Perinatal Factors and Age of Achievement of Full
Oral Feeding in Very Preterm Infants. Pediatrics &
Neonatology, 54 (5), pp.309-314. Link to Abstract
Jonsdottir, OH et al (2014) Exclusive breastfeeding
for 4 versus 6 months and growth in early
childhood. Acta Paediatrica, 103 (1), pp.105-111.
Lambert, LM et al (2014) Variation in Feeding
Practices following the Norwood Procedure. The
Journal of Pediatrics, 164 (2), pp.237-242.e231.
Leite, ME et al (2013) Calcium and fat metabolic
balance, and gastrointestinal tolerance in term
infants fed milk-based formulas with and without
palm olein and palm kernel oils: a randomized
blinded crossover study. BMC Pediatrics, 13,
pp.215. Link to Abstract Link to Full Text
Maas, C et al (2013) Early feeding of fortified
breast milk and in-hospital-growth in very
premature infants: a retrospective cohort
analysis. BMC Pediatrics, 13, pp.178.
Link to Abstract Link to Full Text
Martin, RM et al (2013) Effects of promoting
longer-term and exclusive breastfeeding on
adiposity and insulin-like growth factor-I at age
11.5 years: a randomized trial. JAMA: the Journal
of the American Medical Association, 309 (10),
pp.1005-1013. Link to Abstract Link to Full Text
Northrup, TF et al (2013) Breastfeeding practices
in mothers of high-respiratory-risk NICU infants:
impact of depressive symptoms and smoking.
Journal of Maternal-Fetal and Neonatal Medicine, 26
(18), pp.1838-1843. Link to Abstract
Ross, PA et al (2014) Accuracy of Pulse Oximetry
in Children. Pediatrics, 133 (1), pp.22-29.
Szajewska, H et al (2013) Growth of infants fed
formula supplemented with Bifidobacterium
lactis Bb12 or Lactobacillus GG: a systematic
review of randomized controlled trials. BMC
Pediatrics, 13, pp.185. Link to Abstract
Zhang, L et al (2014) Breast feeding and
immunoprophylaxis efficacy of mother-to-child
transmission of hepatitis B virus. Journal of
Maternal-Fetal and Neonatal Medicine, 27 (2),
pp.182-186. Link to Abstract
Learning Disabilities
Alcoba, G et al (2013) Do children with
uncomplicated severe acute malnutrition need
antibiotics? A systematic review and meta-
analysis. PloS One, 8 (1), pp.e53184.
Link to Abstract Link to Full Text
Al-Owain, M et al (2013) Autism spectrum disorder
in a child with propionic acidemia. JIMD reports, 7,
pp.63-66. Link to Abstract Link to Full Text
Aversa, T et al (2013) In young patients with
Turner or Down syndrome Graves' disease
presentation is often preceded by Hashimoto's
thyroiditis. Thyroid: Official journal of the American
Thyroid Association, Published on line 29th January.
Bueno, JAS et al (2013) New contingent sequential
screening model for Down syndrome based on
the combined test associated with modified
genetic sonography. Journal of Maternal-Fetal and
Neonatal Medicine, 26 (18), pp.1792-1798.
Christensen, J et al (2013) Prenatal valproate
exposure and risk of autism spectrum disorders
and childhood autism. JAMA: the Journal of the
American Medical Association, 309 (16), pp.1696-
1703. Link to Abstract.
Imamura, T et al (2013) Neurodevelopmental
Outcomes of Children with Periventricular
Leukomalacia. Pediatrics & Neonatology, 54 (6),
pp.367-372. Link to Abstract
King, BH et al (2013) Baseline factors predicting
placebo response to treatment in children and
adolescents with autism spectrum disorders: a
multisite randomized clinical trial. JAMA Pediatrics,
167 (11), pp.1045-1052. Link to Abstract
Kotte, A et al (2013) Autistic traits in children with
and without ADHD. Pediatrics, 132 (3), pp.e612-622.
Kuzniewicz, MW et al (2014) Prevalence and
Neonatal Factors Associated with Autism
Spectrum Disorders in Preterm Infants. The
Journal of Pediatrics, 164 (1), pp.20-25.
McCabe, J et al (2013) Nursing, sexual health and
youth with disabilities: a critical ethnography.
Journal of Advanced Nursing, 70 (1), pp. 77-86
Link to Abstract Link to Full Text
Polo-Kantola, P et al (2014) Obstetric Risk Factors
and Autism Spectrum Disorders in Finland. The
Journal of Pediatrics, 164 (2), pp.358-365.
Rance, G et al (2014) The Use of Listening
Devices to Ameliorate Auditory Deficit in
Children with Autism. The Journal of Pediatrics,
164 (2), pp.352-357. Link to Abstract
Robins, DL et al (2014) Validation of the Modified
Checklist for Autism in Toddlers, Revised With
Follow-up (M-CHAT-R/F). Pediatrics, 133 (1), pp.37-
45. Link to Abstract
Silva, D et al (2014) Environmental Risk Factors
by Gender Associated With Attention-
Deficit/Hyperactivity Disorder. Pediatrics, 133 (1),
pp.e14-e22. Link to Abstract
Wong, HS et al (2014) Evaluation of Early
Childhood Social-Communication Difficulties in
Children Born Preterm Using the Quantitative
Checklist for Autism in Toddlers. The Journal of
Pediatrics, 164 (1), pp.26-33.e21. Link to Abstract
Zonfrillo, MR et al (2014) Residual Cognitive
Disability after Completion of Inpatient
Rehabilitation among Injured Children. The
Journal of Pediatrics, 164 (1), pp.130-135.
Mental Health
Chemtob, CM et al (2013) Maternal posttraumatic
stress disorder and depression in pediatric
primary care: association with child maltreatment
and frequency of child exposure to traumatic
events. JAMA Pediatrics, 167 (11), pp.1011-1018.
Duffy, A et al (2013) The developmental trajectory
of bipolar disorder. The British Journal of
Psychiatric: the Journal of Mental Science, 204 (2),
pp. 122-128 Link to Abstract
Hodgkinson, S et al (2014) Addressing the Mental
Health Needs of Pregnant and Parenting
Adolescents. Pediatrics, 133 (1), pp.114-122.
Kassam-Adams, N et al (2013) Posttraumatic
stress following pediatric injury: update on
diagnosis, risk factors, and intervention. JAMA
Pediatrics, 167 (12), pp.1158-1165. Link to Abstract
Marsac, ML et al (2013) Preventing posttraumatic
stress following pediatric injury: a randomized
controlled trial of a web-based psycho-
educational intervention for parents. Journal of
Pediatric Psychology, 38 (10), pp.1101-1111.
Miranda, R et al (2014) Longitudinal follow-up
study of adolescents who report a suicide
attempt: aspects of suicidal behavior that
increase risk of a future attempt. Depression and
anxiety, 31 (1), pp.19-26. Link to Abstract
Syurina, EV et al (2014) Family history of mental1
conditions in the preventive paediatric primary
care: is it really used? Case of the Netherlands.
Acta Paediatrica, 103 (3), pp.309-313.
Venkatesh, KK et al (2014) Accuracy of Brief
Screening Tools for Identifying Postpartum
Depression Among Adolescent Mothers.
Pediatrics, 133 (1), pp.e45-e53. Link to Abstract
Metabolic Disorders
Dai, S et al (2014) Non−High-Density Lipoprotein
Cholesterol: Distribution and Prevalence of High
Serum Levels in Children and Adolescents:
United States National Health and Nutrition
Examination Surveys, 2005-2010. The Journal of
Pediatrics, 164 (2), pp.247-253. Link to Abstract
Koyama, S et al (2014) Adiposity Rebound and the
Development of Metabolic Syndrome. Pediatrics,
133 (1), pp.e114-e119. Link to Abstract
Martin, RM et al (2014) Effects of promoting
longer-term and exclusive breastfeeding on
cardiometabolic risk factors at age 11.5 years: a
cluster-randomized, controlled trial. Circulation,
129 (3), pp.321-329. Link to Abstract
Staiano, AE et al (2014) Cardiometabolic Risk
Factors and Fat Distribution in Children and
Adolescents. The Journal of Pediatrics, 164 (3),
pp.560-565. Link to Abstract
Nephrology
Bansal, D et al (2013) Comparison of Pediatric
Robotic-assisted Laparoscopic
Nephroureterectomy and Laparoendoscopic
Single-site Nephroureterectomy. Urology,83 (2),
pp. 438-442 Link to Abstract
Bonadio, W (2013) Urinary Tract Infection in
Outpatient Febrile Infants Younger than 30 Days
of Age: A 10-Year Evaluation. Pediatric Infectious
Disease Journal, Published online 7th October 2013,
Camargo, M et al (2014) Growth of children with
end-stage renal disease undergoing daily
hemodialysis. Pediatric Nephrology, 29 (3), pp.439-
444. Link to Abstract
Dingemann, C et al (2013) Laparoscopic
transperitoneal heminephrectomy for duplex
kidney in infants and children: a comparative
study. Journal of Laparoendoscopic & Advanced
Surgical Techniques. Part A, 23 (10), pp.889-893.
Filler, G et al (2014) Methods of assessing renal
function. Pediatric Nephrology, 29 (2), pp.183-192.
Gandhi, S et al (2013) Calcium-channel blocker-
clarithromycin drug interactions and acute
kidney injury. JAMA: the Journal of the American
Medical Association, 310 (23), pp.2544-2553.
Garcia-Bello, J et al (2014) Carotid intima media
thickness, oxidative stress, and inflammation in
children with chronic kidney disease. Pediatric
Nephrology, 29 (2), pp.273-281. Link to Abstract
Gunasekara, V et al (2014) C1q nephropathy in
children: clinical characteristics and outcome.
Pediatric Nephrology, 29 (3), pp.407-413.
Hanley, H et al (2014) Identifying Potential Kidney
Donors Among Newborns Undergoing
Circulatory Determination of Death. Pediatrics,
133 (1), pp.e82-e87. Link to Abstract
Ho, J et al (2014) Proteomics in acute kidney
injury—current status and future promise.
Pediatric Nephrology, 29 (2), pp.163-171.
Humes, HD et al (2014) The bioartificial kidney:
current status and future promise. Pediatric
Nephrology, 29 (3), pp.343-351. Link to Abstract
Kida, Y et al (2014) Peritubular capillary
rarefaction: a new therapeutic target in chronic
kidney disease. Pediatric Nephrology, 29 (3),
pp.333-342. Link to Abstract
Laakkonen, H et al (2014) Parent–child and
spousal relationships in families with a young
child with end-stage renal disease. Pediatric
Nephrology, 29 (2), pp.289-295. Link to Abstract
Mangera, A et al (2013) An Updated Systematic
Review and Statistical Comparison of
Standardised Mean Outcomes for the Use of
Botulinum Toxin in the Management of Lower
Urinary Tract Disorders. European Urology,
Published online 1st November. Link to Abstract
Megged, O (2014) Staphylococcus aureus urinary
tract infections in children are associated with
urinary tract abnormalities and vesico-ureteral
reflux. Pediatric Nephrology, 29 (2), pp.269-272.
Mitsnefes, M et al (2014) Ceramides and cardiac
function in children with chronic kidney disease.
Pediatric Nephrology, 29 (3), pp.415-422.
Ozkan, H et al (2013) Culture-proven neonatal
sepsis in preterm infants in a neonatal intensive
care unit over a 7-year period: Coagulase-
negative Staphylococcus as the predominant
pathogen. Pediatrics International: Official Journal of
the Japan Pediatric Society, 56 (1) Link to Abstract
Siomou, E et al (2014) Growth and function in
childhood of a normal solitary kidney from birth
or from early infancy. Pediatric Nephrology, 29 (2),
pp.249-256. Link to Abstract
Sung, J et al (2013) Alemtuzumab induction with
tacrolimus monotherapy in 25 pediatric renal
transplant recipients. Pediatric Transplantation, 17
(8), pp.718-725. Link to Abstract
Symons, J (2014) Moving beyond supportive
care—current status of specific therapies in
pediatric acute kidney injury. Pediatric Nephrology,
29 (2), pp.173-181. Link to Abstract
Tancredi, DJ et al (2014) Pretransplant Serum
Albumin Is an Independent Predictor of Graft
Failure in Pediatric Renal Transplant Recipients.
The Journal of Pediatrics, 164 (3), pp.602-606.
Watson, L et al (2014) Urine biomarkers for
monitoring juvenile lupus nephritis: a
prospective longitudinal study. Pediatric
Nephrology, 29 (3), pp.397-405. Link to Abstract
Woolf, A et al (2014) Genetics of human congenital
urinary bladder disease. Pediatric Nephrology, 29
(3), pp.353-360. Link to Abstract
Neurology
Dagalakis, U et al (2014) Puberty and Plexiform
Neurofibroma Tumor Growth in Patients with
Neurofibromatosis Type I. The Journal of Pediatrics,
164 (3), pp.620-624. Link to Abstract
Gray, N et al (2014) The effect of continuous
intrathecal baclofen on sitting in children with
severe cerebral palsy. European Journal of
Paediatric Neurology, 18 (1), pp.45-49.
Grønborg, S et al (2014) Mortality and causes of
death in children referred to a tertiary epilepsy
center. European Journal of Paediatric Neurology,
18 (1), pp.66-71. Link to Abstract
Grosso, S et al (2014) Efficacy and safety of
lacosamide in infants and young children with
refractory focal epilepsy. European Journal of
Paediatric Neurology, 18 (1), pp.55-59.
Mankinen, K et al (2014) Neuropsychological
performance in children with temporal lobe
epilepsy having normal MRI findings. European
Journal of Paediatric Neurology, 18 (1), pp.60-65.
Musselman, KE et al (2013) Prevalence of ataxia in
children: A systematic review. Neurology, 82 (1),
pp. 80-89 Link to Abstract
Porto, L et al (2014) Conventional magnetic
resonance imaging in the differentiation between
high and low-grade brain tumours in paediatric
patients. European Journal of Paediatric Neurology,
18 (1), pp.25-29. Link to Abstract
Powers, SW et al (2013) Cognitive behavioral
therapy plus amitriptyline for chronic migraine in
children and adolescents: a randomized clinical
trial. JAMA: the Journal of the American Medical
Association, 310 (24), pp.2622-2630. Link to Abstract
Ramantani, G et al (2014) Epilepsy in Aicardi–
Goutières syndrome. European Journal of
Paediatric Neurology, 18 (1), pp.30-37.
Risen, SR et al (2014) Functional Outcomes in
Children with Abusive Head Trauma Receiving
Inpatient Rehabilitation Compared with Children
with Nonabusive Head Trauma. The Journal of
Pediatrics, 164 (3), pp.613-619.e612. Link to Abstract
Romaniello, R et al (2013) A Novel Mutation in
STXBP1 Gene in a Child With Epileptic
Encephalopathy and an Atypical Electroclinical
Pattern. Journal of Child Neurology, 29 (2), pp.
249-253 Link to Abstract
Sakzewski, L et al (2014) Efficacy of Upper Limb
Therapies for Unilateral Cerebral Palsy: A Meta-
analysis. Pediatrics, 133 (1), pp.e175-e204.
Link to Abstract Link to Full Text
Sánchez Fernández, I et al (2014) Electrographic
Seizures after Convulsive Status Epilepticus in
Children and Young Adults: A Retrospective
Multicenter Study. The Journal of Pediatrics, 164
(2), pp.339-346.e332. Link to Abstract
Sarrazin, E et al (2014) Growth and psychomotor
development of patients with Duchenne muscular
dystrophy. European Journal of Paediatric
Neurology, 18 (1), pp.38-44. Link to Abstract
Tsai, M-C et al (2014) Mood Disorders after
Traumatic Brain Injury in Adolescents and Young
Adults: A Nationwide Population-Based Cohort
Study. The Journal of Pediatrics, 164 (1), pp.
136-141.e131. Link to Abstract
Verrotti, A et al (2014) Valproate in adolescents
with photosensitive epilepsy with generalized
tonic–clonic seizures only. European Journal of
Paediatric Neurology, 18 (1), pp.13-18.
Zotter, S et al (2013) Neuropsychological profile of
children after an episode of neuroborreliosis.
Neuropediatrics, 44 (6), pp.346-353. Link to Abstract
Nutrition, Diet & Obesity
Abreu, S et al (2014) Relationship of milk intake
and physical activity to abdominal obesity among
adolescents. Pediatric Obesity, 9 (1), pp.71-80.
Alcoba, G et al (2013) Do children with
uncomplicated severe acute malnutrition need
antibiotics? A systematic review and meta-
analysis. PloS One, 8 (1), pp.e53184.
Link to Abstract Link to Full Text
Atkinson, MA et al (2014) Vitamin D, Race, and
Risk for Anemia in Children. The Journal of
Pediatrics, 164 (1), pp.153-158.e151.
Chandler-Laney, PC et al (2014) Gut hormone
activity of children born to women with and
without gestational diabetes. Pediatric Obesity, 9
(1), pp.53-62. Link to Abstract
Cuenca-García, M et al (2014) More Physically
Active and Leaner Adolescents Have Higher
Energy Intake. The Journal of Pediatrics, 164 (1),
pp.159-166.e152. Link to Abstract
Feskanich, D et al (2014) Milk consumption during
teenage years and risk of hip fractures in older
adults. JAMA Pediatrics, 168 (1), pp.54-60.
Haines, J et al (2013) Healthy Habits, Happy
Homes: randomized trial to improve household
routines for obesity prevention among preschool-
aged children. JAMA Pediatrics, 167 (11), pp.1072-
1079. Link to Abstract
Hannon, TS et al (2014) Morning Blood Pressure Is
Associated with Sleep Quality in Obese
Adolescents. The Journal of Pediatrics, 164 (2),
pp.313-317. Link to Abstract
Hendrie, G et al (2013) Change in the family food
environment is associated with positive dietary
change in children. The International Journal of
Behavioral Nutrition and Physical Activity, 10, pp.4.
Link to Abstract Link to Full Text
Hollinghurst, S et al (2014) Cost and effectiveness
of treatment options for childhood obesity.
Pediatric Obesity, 9 (1), pp.e26-e34.
Kjölhede, EA et al (2014) Overweight and obese
children have lower cortisol levels than normal
weight children. Acta Paediatrica, 103 (3), pp.295-
299. Link to Abstract
Kokkvoll, A et al (2014) Single versus multiple-
family intervention in childhood overweight-
Finnmark Activity School: a randomised trial.
Archives of Disease in Childhood, 99 (3), pp.225-231.
Link to Abstract Link to Full Text
Low, M et al (2013) Effects of daily iron
supplementation in primary-school-aged
children: systematic review and meta-analysis of
randomized controlled trials. CMAJ : Canadian
Medical Association Journal = journal de
l'Association Medicale Canadienne, 185 (17),
pp.E791-802. Link to Abstract Link to Full Text
Maggio, AB et al (2013) BMI changes in children
and adolescents attending a specialized
childhood obesity center: a cohort study. BMC
Pediatrics, 13, pp.216. Link to Abstract
Mareno, N (2014) Parental perception of child
weight: a concept analysis. Journal of Advanced
Nursing, 70 (1), pp. 34-45 Link to Abstract
McDonagh, MS et al (2013) Systematic Review of
the Benefits and Risks of Metformin in Treating
Obesity in Children Aged 18 Years and Younger.
JAMA Pediatrics, 168 (2), pp. 178-184.
Morandi, A et al (2014) Screening for impaired
glucose tolerance in obese children and
adolescents: a validation and implementation
study. Pediatric Obesity, 9 (1), pp.17-25.
Neyestani, TR et al (2013) Calcium-vitamin D-
fortified milk is as effective on circulating bone
biomarkers as fortified juice and supplement but
has less acceptance: a randomised controlled
school-based trial. Journal of Human Nutrition and
Dietetics : the official journal of the British Dietetic
Association, Published Online 25th November
Nyaradi, A et al (2013) Diet in the early years of life
influences cognitive outcomes at 10 years: a
prospective cohort study. Acta Paediatrica, 102
(12), 1165-1173 Link to Abstract.
Schroth, RJ et al (2013) Vitamin D status of
children with severe early childhood caries: a
case-control study. BMC Pediatrics, 13, pp.174.
Link to Abstract Link to Full Text
Schusterova, I et al (2014) Epicardial adipose
tissue and cardiometabolic risk factors in
overweight and obese children and adolescents.
Pediatric Obesity, 9 (1), pp.63-70. Link to Abstract
Steinberg, N et al (2013) The effect of a weight
management program on postural balance in
obese children. European Journal of Pediatrics, 172
(12), pp.1619-1626. Link to Abstract
Timmermans, SH et al (2014) Maternal smoking
during pregnancy and childhood overweight and
fat distribution: the KOALA Birth Cohort Study.
Pediatric Obesity, 9 (1), pp.e14-e25. Link to Abstract
Tognon, G et al (2013) Mediterranean diet,
overweight and body composition in children
from eight European countries: Cross-sectional
and prospective results from the IDEFICS study.
Nutrition, Metabolism, and Cardiovascular Diseases:
NMCD, 24 (2), pp. 205-213 Link to Abstract
Veses, AM et al (2014) Physical fitness,
overweight and the risk of eating disorders in
adolescents. The AVENA and AFINOS studies.
Pediatric Obesity, 9 (1), pp.1-9. Link to Abstract
Wansink, B et al (2014) Larger Bowl Size Increases
the Amount of Cereal Children Request,
Consume, and Waste. The Journal of Pediatrics,
164 (2), pp.323-326. Link to Abstract
Zegers, D et al (2014) Screening for genetic
variants in BDNF that contribute to childhood
obesity. Pediatric Obesity, 9 (1), pp.36-42.
Oncology
Caselli, D et al (2014) Single-Day
Trimethoprim/Sulfamethoxazole Prophylaxis for
Pneumocystis Pneumonia in Children with
Cancer. The Journal of Pediatrics, 164 (2), pp.
389-392.e381. Link to Abstract
Ferrari, A et al (2014) Cutaneous Melanoma in
Children and Adolescents: The Italian Rare
Tumors in Pediatric Age Project Experience. The
Journal of Pediatrics, 164 (2), pp.376-382.e372.
Hedén, L et al (2014) Effect of high-dose
paracetamol on needle procedures in children
with cancer – a RCT. Acta Paediatrica, 103 (3),
pp.314-319. Link to Abstract
Stary, J et al (2014) Intensive Chemotherapy for
Childhood Acute Lymphoblastic Leukemia:
Results of the Randomized Intercontinental Trial
ALL IC-BFM 2002. Journal of Clinical Oncology:
Official Journal of the American Society of Clinical
Oncology, 32 (3), pp.174-184. Link to Abstract
Wu, LM et al (2013) Evaluating the acceptability
and efficacy of a psycho-educational intervention
for coping and symptom management by
children with cancer: a randomized controlled
study. Journal of Advanced Nursing, Published
Online 23rd December Link to Abstract
Pharmacology & Therapeutics
Hersh, AL et al (2014) Linezolid Use in
Hospitalized Children. The Pediatric Infectious
Disease Journal, 33 (1), pp.e14-e18
Shah, R et al (2014) Communicating Doses of
Pediatric Liquid Medicines to Parents/Caregivers:
A Comparison of Written Dosing Directions on
Prescriptions with Labels Applied by Dispensed
Pharmacy. The Journal of Pediatrics, 164 (3),
pp.596-601.e591. Link to Abstract
Star, K et al (2014) Pharmacovigilance for
Children's Sake. Drug Safety: an International
Journal of Medical Toxicology and Drug Experience,
37 (2), pp.91-98. Link to Abstract
Valkhoff, VE et al (2013) Population-based
analysis of non-steroidal anti-inflammatory drug
use among children in four European countries in
the SOS project: what size of data platforms and
which study designs do we need to assess safety
issues? BMC Pediatrics, 13, pp.192. Link to Abstract
Yang, M et al (2013) Revisiting the Safety of Over-
the-Counter Cough and Cold Medications in the
Pediatric Population. Clinical Pediatrics, 53 (4), pp.
326-230. Link to Abstract
Reproduction & Sexual Health
Asheer, S et al (2014) Engaging Pregnant and
Parenting Teens: Early Challenges and Lessons
Learned From the Evaluation of Adolescent
Pregnancy Prevention Approaches. The Journal of
Adolescent Health: Official Publication of the Society
for Adolescent Medicine, 54 (3), pp.S84-S91.
Link to Abstract Link to Full Text
Farb, AF et al (2014) From Mission to Measures:
Performance Measure Development for a Teen
Pregnancy Prevention Program. The Journal of
Adolescent Health: Official Publication of the Society
for Adolescent Medicine, 54 (3), pp.S15-S20.
Harrison, K et al (2014) Sexual health in young
people with connective tissue disorders.
Paediatrics and Child Health, 24 (2), pp.72-77.
Kappeler, EM et al (2014) Historical Context for the
Creation of the Office of Adolescent Health and
the Teen Pregnancy Prevention Program. The
Journal of Adolescent Health: Official Publication of
the Society for Adolescent Medicine, 54 (3), pp.S3-
S9. Link to Abstract Link to Full Text
Kelsey, M et al (2014) Implementing Three
Evidence-Based Program Models: Early Lessons
From the Teen Pregnancy Prevention Replication
Study. The Journal of Adolescent Health: Official
Publication of the Society for Adolescent Medicine,
54 (3), pp.S45-S52. Link to Abstract
Layzer, C et al (2014) A Peer Education Program:
Delivering Highly Reliable Sexual Health
Promotion Messages in Schools. The Journal of
Adolescent Health: Official Publication of the Society
for Adolescent Medicine, 54 (3), pp.S70-S77.
Link to Abstract Link to Full Text
Respiratory Disorders
Accinelli, RA et al (2014) Adherence to reduced-polluting biomass fuel stoves improvesrespiratory and sleep symptoms in children. BMC Pediatrics, 14 (1), pp.12. Link to Abstract Link to Full Text
Afsharpaiman, S et al (2013) Respiratory difficulties and breathing disorders in achondroplasia. Paediatric Respiratory Reviews, 14 (4), pp.250-255. Link to Abstract
Akenroye, AT et al (2014) Impact of a Bronchiolitis Guideline on ED Resource Use and Cost: A Segmented Time-Series Analysis. Pediatrics, 133 (1), pp.e227-e234. Link to Abstract
Alansari, K et al (2013) Oral dexamethasone for bronchiolitis: a randomized trial. Pediatrics, 132 (4), pp.e810-816. Link to Abstract.
Albuali, WH (2014) The use of intravenous and inhaled magnesium sulphate in management of children with bronchial asthma. Journal of Maternal-Fetal and Neonatal Medicine, Published on line 30th January. Link to Abstract
Bekhof, J et al (2014) Systematic review: Insufficient validation of clinical scores for the assessment of acute dyspnoea in wheezing children. Paediatric Respiratory Reviews, 15 (1), pp.98-112. Link to Abstract
Borckink, I et al (2014) Infants with severe respiratory syncytial virus needed less ventilator time with nasal continuous airways pressure then invasive mechanical ventilation. Acta Paediatrica, 103 (1), pp.81-85. Link to Abstract
Briana, DD et al (2013) Small for gestational age birth weight: impact on lung structure and function. Paediatric Respiratory Reviews, 14 (4), pp.256-262. Link to Abstract
Britto, MT et al (2014) Improving Outcomes for Underserved Adolescents With Asthma. Pediatrics, 133 (2), pp.e418-e427. Link to Abstract
Cardinale, F et al (2013) Community-acquired pneumonia in children. Early Human Development, 89, pp.S49-S52. Link to Abstract
Carraro, S et al (2013) Bronchopulmonary dysplasia: The earliest and perhaps the longest lasting obstructive lung disease in humans. Early Human Development, 89, pp.S3-S5. Link to Abstract
Catanzaro, T et al (2014) Somatic Growth and Lung Function in Sickle Cell Disease. Paediatric Respiratory Reviews, 15 (1), pp.28-32. Link to Abstract
Cazzato, S et al (2013) Interstitial lung disease in children. Early Human Development, 89, pp.S39- S43. Link to Abstract
Chen, JS et al (2013) Simple aspiration and drainage and intrapleural minocycline pleurodesis versus simple aspiration and drainage for the initial treatment of primary spontaneous pneumothorax: an open-label, parallel-group, prospective, randomised, controlled trial. Lancet, 381 (9874), pp.1277-1282. Link to Abstract
Coclite, E et al (2013) Congenital and perinatal cytomegalovirus lung infection. Journal of Maternal-Fetal and Neonatal Medicine, 26 (17), pp.1671-1675. Link to Abstract
Cossette, B et al (2013) Impact of maternal use of asthma-controller therapy on perinatal outcomes. Thorax, 68 (8), pp.724-730. Link to Abstract ink to Full Text
Crider, KS et al (2013) Prenatal folic acid and riskof asthma in children: a systematic review and meta-analysis. The American Journal of Clinical Nutrition, 98 (5), pp.1272-1281. Link to Abstract
Fouzas, S et al (2014) Volumetric Capnography in Infants with Bronchopulmonary Dysplasia. The Journal of Pediatrics, 164 (2), pp.283-288.e283. Link to Abstract
Harju, M et al (2014) The Burden of Childhood Asthma and Late Preterm and Early Term Births. The Journal of Pediatrics, 164 (2), pp.295-299.e291.Link to Abstract
Hollams, EM et al (2013) Persistent Effects of Maternal Smoking during Pregnancy on Lung Function and Asthma in Adolescents. American Journal of Respiratory and Critical Care Medicine, 189 4), pp. 401-407 Link to Abstract
Jacobs, JD et al (2014) 7% Hypertonic Saline in Acute Bronchiolitis: A Randomized Controlled Trial. Pediatrics, 133 (1), pp.e8-e13. Link to Abstract
Jang, J et al (2013) Trends in cost and outcomes among adult and pediatric patients with asthma: 2000-2009. Annals of Allergy, Asthma & Immunology: Official Publication of the American College of Allergy, Asthma, & Immunology, 111 (6), pp.516-522. Link to Abstract
Kantar, A et al (2013) Chronic cough in preschool children. Early Human Development, 89, pp.S19- S24. Link to Abstract
Kenyon, CC et al (2014) Rehospitalization for Childhood Asthma: Timing, Variation, and Opportunities for Intervention. The Journal of Pediatrics, 164 (2), pp.300-305. Link to Abstract
Koumbourlis, AC (2014) Lung Function in Sickle Cell Disease. Paediatric Respiratory Reviews, 15 (1), pp.33-37. Link to Abstract
Lee, S et al (2013) Tracheobronchomalacia in infants: The use of non-breath held 3D CT bronchoscopy. Pediatric Pulmonology, Published Online 25th October. Link to Abstract
Little, P et al (2013) Ibuprofen, paracetamol, and steam for patients with respiratory tract infections in primary care: pragmatic randomised factorial trial. BMJ (Clinical research ed.), 347, pp.f6041. Link to Abstract Link to Full Text
Lodge, CJ et al (2014) Early-Life Risk Factors for Childhood Wheeze Phenotypes in a High-Risk Birth Cohort. The Journal of Pediatrics, 164 (2), pp.289-294.e282. Link to Abstract
Massie, J et al (2013) Cystic Fibrosis CarrierScreening. Paediatric Respiratory Reviews, 14 (4),pp.270-275. Link to Abstract
Mattes, J et al (2014) Prenatal origins of bronchiolitis: protective effect of optimised asthma management during pregnancy. Thorax, 69 (4), pp. 383-384. Link to Abstract Link to Full Text
McBride, JJ et al (2014) Hypnosis in Paediatric Respiratory Medicine. Paediatric RespiratoryReviews, 15 (1), pp.82-85. Link to Abstract
Mikalsen, IB et al (2014) Blood eosinophil countsduring bronchiolitis are related to bronchial hyper-responsiveness and lung function in early adolescence. Acta Paediatrica, 103 (1), pp.86-92. Link to Abstract
Norman, G et al (2013) Omalizumab for the treatment of severe persistent allergic asthma: a systematic review and economic evaluation. Health Technology Assessment (Winchester, England), 17 (52), pp.1-342. Link to Abstract Link to Full Text
Papenburg, J et al (2013) Host and viral factors affecting clinical performance of a rapid diagnostic test for respiratory syncytial virus in hospitalized children. The Journal of Pediatrics, 163 (3), pp.911-913. Link to Abstract
Parikh, K et al (2014) Bronchiolitis Management Before and After the AAP Guidelines. Pediatrics, 133 (1), pp.e1-e7. Link to Abstract
Pavone, M et al (2013) Non-invasive positive pressure ventilation in children. Early Human Development, 89, pp.S25-S31. Link to Abstract
Powell, CV et al (2013) MAGNEsium Trial In Children (MAGNETIC): a randomised, placebo-controlled trial and economic evaluation of nebulised magnesium sulphate in acute severe asthma in children. Health Technology Assessment (Winchester, England), 17 (45), pp.v-vi, 1-216. Link to Abstract Link to Full Text
Queen, MA et al (2014) Comparative Effectiveness of Empiric Antibiotics for Community-Acquired Pneumonia. Pediatrics, 133 (1), pp.e23-e29. Link to Abstract
Ringholz, F et al (2014) Managing End Stage Lung Disease in Children. Paediatric Respiratory Reviews, 15 (1), pp.75-81. Link to Abstract
Rotzén-Östlund, M et al (2014) Children with multiple viral respiratory infections are older than those with single viruses. Acta Paediatrica, 103 (1),pp.100-104. Link to Abstract Link to Full Text
Rubin, BK (2014) Cystic fibrosis: Myths. mistakes,and dogma. Paediatric Respiratory Reviews, 15 (1), pp.113-116. Link to Abstract
Tappenden, P et al (2013) Colistimethate sodium powder and tobramycin powder for inhalation for the treatment of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis: systematic review and economic model. Health Technology Assessment (Winchester, England), 17 (56), pp.v-xvii, 1-181. Link to Abstract Link to Full Text
Tiddens, HAWM et al (2014) Multi-modality monitoring of cystic fibrosis lung disease: The role of chest computed tomography. Paediatric Respiratory Reviews, 15 (1), pp.92-97. Link to Abstract
Tsai, K-S et al (2013) Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination. Pediatrics & Neonatology, 54 (5), pp.295-302. Link to Abstract
vom Hove, M et al (2014) Pulmonary Outcome in Former Preterm, Very Low Birth Weight Children with Bronchopulmonary Dysplasia: A Case-Control Follow-Up at School Age. The Journal of Pediatrics, 164 (1), pp.40-45.e44.Link to Abstract
Woodcock, A et al (2013) Efficacy and safety of fluticasone furoate/vilanterol compared with fluticasone propionate/salmeterol combination in adult and adolescent patients with persistent asthma: a randomized trial. Chest, 144 (4), pp.1222-1229. Link to Abstract Link to Full Text
Yu, D et al (2014) Seventeen-year study shows rise in parapneumonic effusion and empyema with higher treatment failure after chest tube drainage. Acta Paediatrica, 103 (1), pp.93-99.Link to Abstract Link to Full Text
Zahran, HS et al (2014) Assessing asthma severity among children and adults with current asthma. The Journal of Asthma: Official Journal of the Association for the Care of Asthma, Published Online 6th March. Link to Abstract
Zomer-Kooijker, K et al (2014) Lack of Long-term Effects of High-dose Inhaled Beclomethasone for Respiratory Syncytial Virus Bronchiolitis: A Randomized Placebo-controlled Trial. The Pediatric Infectious Disease Journal, 33 (1), pp.19-23 Link to Abstract
Rheumatology Disorders
Aggarwal, R et al (2013) Predictors of clinical improvement in rituximab-treated refractory adult and juvenile dermatomyositis and adult polymyositis. Arthritis and Rheumatism, 66 (3), pp.740-749 Link to Abstract
Armon, K (2014) Outcomes for Juvenile idiopathic arthritis. Paediatrics and Child Health, 24 (2), pp.64- 71. Link to Abstract
Cohen, A et al (2014) Physiotherapy and rheumatological disorders Paediatrics and Child Health, 24 (2), pp.83-88. Link to Abstract
Nistala, K et al (2013) Update in juvenile myositis. Current Opinion in Rheumatology, 25 (6), pp.742-746. Link to Abstract
Sudden Infant Death
Colson, ER et al (2013) Trends and factors associated with infant bed sharing, 1993-2010: the National Infant Sleep Position Study. JAMA Pediatrics, 167 (11), pp.1032-1037. Link to Abstract Link to Full Text
Huang, Y et al (2013) Influence of bedsharing activity on breastfeeding duration among US mothers. JAMA Pediatr, 167 (11), pp.1038-1044.Link to Abstract
Putnam-Hornstein, E et al (2014) A Prospective Study of Sudden Unexpected Infant Death after Reported Maltreatment. The Journal of Pediatrics, 164 (1), pp.142-148. Link to Abstract
