Bullous pemphigoid- August 2011



August 2011 - Issue 3



Bullous Pemphigoid/Pemphigus Vulgaris


This  fact  sheet   provides   a  2011   overview  of  recent  evidence   relevant   to  bullous   pemphigoid   and

pemphigus vulgaris and also information on how the “Outreach Librarian Service” can support you to

keep up-to-date .


Selected Evidence


Clinical Trials

Thirteen studies of bullous pemphigoid at http://clinicaltrials.gov/ct2/results?term=Bullous+Pemphigoid




Batalla A, Peon G & De la Torre C

Localized bullous pemphigoid at urostomy site

Indian Journal of Dermatology Venereology Leprology September/October 2011: 77(5) p 625


Cortes B, Marazza G, Naldi L, Combescure C, Borradori L & the Autoimmune Bullous Disease

Swiss Study Group

Mortality of bullous pemphigoid in Switzerland: a prospective study

British Journal of Dermatology August 2011: 165(2) 368-374


Di Zenzo G, Thoma-Uszynski S, Calabresi V, Fontao L & Hofmann SC

Demonstration of Epitope-spreading phenomena in bullous pemphigoid: results of a prospective

multicenter study

Journal Investigative Dermatology June 23 2011


Du-Thanh A, Merlet S, Maillard H, Bernard P, Joly P & Esteve E

Combined treatment with low-dose methotrexate and initial short-term superpotent topical steroids

in bullous pemphigoid: An open multicenter, retrospective study

British Journal of Dermatology July 20 2011


Durdu M, Baba M & Seckin D

A case of bullous pemphigoid induced by aspirin

Journal American Academy Dermatology August 2011: 65(2) p 443-4


Kasperkiewicz M, Shimanovich I, Ludwig RJ, Rose C, Zillikens D & Schmidt E

Rituximab for treatment-refractory pemphigus and pemphigoid: a case of 17 patients

Journal of the American Academy of Dermatology September 2011: 65(3) 552-8


Khandpur S & Verma P

Bullous pemphigoid

Indian Journal of Dermatology Venereology Leprology July/August 2011: p 450-5


Kluck J, Goulding JM, Bhat J & Finch TM

Drug-induced bullous pemphigoid: cases triggered by intravenous iodine and Etanercept

Clinical Experimental Dermatology May 30 2011


Kluger N, Navarro R, Pallure V & Guillot B

Bullous pemphigoid and acquired haemophilial

Annals of Dermatology Venereology May 2011: 138(5) 422-3

Kluger N, Laipio J, Virolainen S, Ranki A & Koljonen V

A fatal case of hot air sauna burn in an elderly patient initially misdiagnosed as bullous pemphi-


Acta Dermatalogical Venereology July 5 2011: p 91


Pasmatzi E, Moastirli A, Habeos J, Georgiou S & Tsambaos D

Dipeptidyl peptidase-4 inhibitors cause bullous pemphigoid in diabetic patients: report of two cases

Diabetes Care August 2011: 34(8) e133


Rodriguez-Caruncho C, Bielsa I, Bayes B, Guinovart R, & Fernandez-Fiqueras T

Bullous pemphigoid associated with chronic renal allograft rejection: resolution after


Journal American Academy Dermatology September 2011: 65(3) e89-90


Schmidt E, della Torre R & Borradori L

Clinical features and practical diagnosis in bullous pemphigoid

Dermatalogical Clinics July 2011: 29(3) 511-3


Singh S

Evidence-based treatments for pemphigus vulgaris, pemphigus foliaceus and bullous pemphigoid:

A systematic review

Indian Journal of Dermatology Venereology Leprology July/August 2011: 77(4) p 456-69


Stevenson ML & Levitt JO

Acute zoster in known pemphigus vulgaris and bullous pemphigoid avoiding the “disease flare”

Journal American Academy Dermatology June 2011: 64(6) e125-6

Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult the first

time you use it


Sticherling M & Erfurt-Berge C

Autoimmune blistering diseases of the skin

Autoimmunity Reviews May 2011: Epub ahead of print


Tosti A, Andre M & & Murrell DF

Nail involvement in autoimmune bullous disorders

Dermatology Clinics July 2011: 29(3) 511-3


Ujiie H, Nishie W & Shimizu H

Pathogenesis of bullous pemphigoid

Dermatalogical Clinics July 2011: 29(3) 439-46


Yayli S, Pelivani N, Beltraminelli H, Wirthmuller U, Beleznay Z, Horn M & Borradori L

Detection of linear IgE deposits in bullous pemphigoid and mucous membrane pemphigoid: a use-

ful clue for diagnosis

British Journal of Dermatology June 28 2011


Zanella RR, Xavier TA, Tebcherani AJ, Aoki V & Sanchez AP

Bullous pemphigoid in younger adults: three case reports

Anais Brasileiros de Dermatologia April 2011: 86(2) 355-8


Pemphigus Vulgaris


Caldarola G & Feliciani C

A glass of red wine to keep vascular disease at bay, but what about pemphigus vulgaris?

Expert Review of Clinical Immunology March 2011: 7(2) 187-91


Fiorentino DF, Garcia MS, Rehmus W & Kimball AB

A pilot study of etanercept treatment for pemphigus vulgaris

Archives of Dermatology January 2011: 147(1) 117-8

Available in fulltext at Highwire Press

Fujii M, Honma M, Iinuma S, Kaneta K, Komatsu S, Sato K & Takahashi H

Recalcitrant facial pemphigus vulgaris: correlation of skin lesions with the ratio of antidesmoglein

antibodies 1 and 3

Clinical & Experimental Dermatology April 2011: 36(3) 284-7


Kalantari-Dehaghi M, Molina DM, Farhadieh M, Morrow WJ, Liang X & Felgner PL

New targets of pemphigus vulgaris antibodies identified by protein array technology

Experimental Dermatology February 2011: 20(2) 154-6


Lanza A, Lanza M, Santoro R, Soro V, Prime SS & Cirillo N

Deregulation of PERK in the autoimmune disease pemphigus vulgaris occurs via IgG-independent


British Journal of Dermatology February 2011: 164(2) 336-43


Marker M, Derfler K, Monshi B & Rappersberger K

Successful immunoapheresis of bullous autoimmune diseases: pemphigus vulgaris and pemphigoid


Journal der Deutschen Dermatologischen Gesellschaft January 2011: 9(1) 27-31


Martin LK & Murrell DF

Pemphigus: Directions for the future

Journal of the American Academy of Dermatology May 2011: 64(5) 909-10

Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult

the first time you use it.


Martin LK, Werth VP, Villaneuva EV & Murrell DF

A systematic review of randomized controlled trials for pemphigus vulgaris and pemphigus foliaceus

Journal of the American Academy of Dermatology May 2011: 64(5) 903-8

Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult

the first time you use it.


Mazzotti E, Mozzetta A, Antinone V, Alfani S, Cianchini G & Abeni D

Psychological distress and investment in one's appearance in patients with pemphigus

Journal of the European Academy of Dermatology & Venereology March 2011: 25(3) 285-9


Strowd LC, Taylor SL, Jorizzo JL & Namazi      MR

Therapeutic ladder for pemphigus vulgaris: emphasis on achieving complete remission

Journal of the American Academy of Dermatology March 2011: 64(3) 490-4

Available in fulltext at MD Consult; Note: You will need to register (free of charge) with MD Consult

the first time you use it.


Oliveira DP, Moura HH, Janini ME, Fernandes NC & SantosN

Diagnosis and treatment of persistent oral lesions caused by herpesvirus in a patient with pemphigus


International Journal of Dermatology March 2011: 50(3) 335-9


Parker SR & MacKelfresh J

Autoimmune blistering diseases in the elderly

Clinics in Dermatology January 2011: 29(1) 69-79


Ragab N, Abdallah M, El-Gohary E & Elewa R

Stress and serum TNF-alpha levels may predict disease outcome in patients with pemphigus:

a preliminary study

Cutis April 2011: 87(4) 189-94


Sagi L, Baum S, Gendelman V, Trau H & Barzilai A

The role of therapeutic plasma exchange in pemphigus vulgaris

Journal of the European Academy of Dermatology & Venereology January 2011: 25(1) 82-6

Wada N, Nishifuji K, Yamada T, Kudoh J, Shimizu N, Matsumoto M &       Peltonen L

Aire-dependent thymic expression of desmoglein 3, the autoantigen in pemphigus vulgaris, and its role

in T-cell tolerance

Journal of Investigative Dermatology February 2011: 131(2) 410-7


Watanabe T, Kato M, Yoshida Y, Fukuda S, Hashimoto T & Yamamoto O

Mucocutaneous-type pemphigus vulgaris with anti-desmoplakin autoantibodies

European Journal of Dermatology, March 2011: 21(2) 299-300



How can I help you?


Literature search service

I can offer an expert, in-depth literature search service to help you locate the evidence on any health

related topic.



If you want to learn to navigate the wealth of available online healthcare information and how to search

databases more effectively, the ‘Trust trainer’ can offer timetabled hands-on training sessions or can

provide customised one-to-one support. Telephone: 0121 424 0583 or email:

[email protected]


Current awareness services

If you need to keep up-to-date on a particular topic I can advise on suitable RSS feeds and help you set

up article alerts from the major healthcare databases.


Online resources

Whilst many good quality resources are freely available, most full-text journals and the main biblio-

graphic databases (e.g. Medline and CINAHL) require an Athens username and password. To register

for an Athens login go to www.athens.nhs.uk      or www.evidence.nhs.uk


The Library web pages contain detailed information about library services and training opportunities,

online request and registration forms and several guides on key online resources and evidence-based

websites at   www.heftlibrary.nhs.uk



The Outreach Librarian is located in the education centre at Heartlands Hospital, on the first floor, next

to the Library.

Telephone 0121 424 2503 (42503) or email: [email protected]